Category: 52378-63-9

Chen, Qingping et al. published their research in Journal of Heterocyclic Chemistry in 1992 | CAS: 52378-63-9

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Formula: C6H8N2O

Synthesis of some benzo[b][1,8] and [1,5]naphthyridines was written by Chen, Qingping;Deady, Leslie W.. And the article was included in Journal of Heterocyclic Chemistry in 1992.Formula: C6H8N2O The following contents are mentioned in the article:

A series of carboxylic acid derivatives of the title compounds, e.g. I and II, were prepared as precursors of potential anti-tumor compounds, by annulation of 2-methylcyclohexanone to the appropriate aminopyridinecarboxaldehyde followed by aromatization and oxidation of the Me group. This study involved multiple reactions and reactants, such as (3-Aminopyridin-2-yl)methanol (cas: 52378-63-9Formula: C6H8N2O).

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Formula: C6H8N2O

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chrostowska, A. et al. published their research in Polish Journal of Chemistry in 2003 | CAS: 52378-63-9

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Recommanded Product: (3-Aminopyridin-2-yl)methanol

UV photoelectron spectroscopy studies of the diazaxylylenes generated from amino(hydroxymethyl)pyridines was written by Chrostowska, A.;Sotiropoulos, J.-M.;Pfister-Guillouzo, G.;Wojciechowski, K.. And the article was included in Polish Journal of Chemistry in 2003.Recommanded Product: (3-Aminopyridin-2-yl)methanol The following contents are mentioned in the article:

Diazaxylylenes generated by 1,4-elimination of water from amino(hydroxymethyl)pyridines under flash vacuum thermolysis (FVT) conditions can be directly studied by the UV-photoelectron spectroscopy (UV-PES). The elimination of water from these compounds starts at 450° and is completed at 500-550°. The interpretation of UV-photoelectron spectra was supported by D. Functional Theory studies. This study involved multiple reactions and reactants, such as (3-Aminopyridin-2-yl)methanol (cas: 52378-63-9Recommanded Product: (3-Aminopyridin-2-yl)methanol).

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Recommanded Product: (3-Aminopyridin-2-yl)methanol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zhao, Yating et al. published their research in Organic Letters in 2016 | CAS: 52378-63-9

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Safety of (3-Aminopyridin-2-yl)methanol

Sunlight-Driven Forging of Amide/Ester Bonds from Three Independent Components: An Approach to Carbamates was written by Zhao, Yating;Huang, Binbin;Yang, Chao;Chen, Qingqing;Xia, Wujiong. And the article was included in Organic Letters in 2016.Safety of (3-Aminopyridin-2-yl)methanol The following contents are mentioned in the article:

A photoredox catalytic route to carbamates enabled by visible irradiation (or simply sunlight) has been developed. This process leads to a novel approach to the construction of heterocyclic rings wherein the amide or ester motifs of carbamates were assembled from three isolated components. Large-scale experiments were realized by employing continuous flow techniques, and reuse of photocatalyst demonstrated the green and sustainable aspects of this method. This study involved multiple reactions and reactants, such as (3-Aminopyridin-2-yl)methanol (cas: 52378-63-9Safety of (3-Aminopyridin-2-yl)methanol).

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Safety of (3-Aminopyridin-2-yl)methanol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xiong, Biao et al. published their research in Organic Letters in 2017 | CAS: 52378-63-9

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Quality Control of (3-Aminopyridin-2-yl)methanol

Ruthenium-Catalyzed Direct Synthesis of Semisaturated Bicyclic Pyrimidines via Selective Transfer Hydrogenation was written by Xiong, Biao;Jiang, Jingxing;Zhang, Shudi;Jiang, Huanfeng;Ke, Zhuofeng;Zhang, Min. And the article was included in Organic Letters in 2017.Quality Control of (3-Aminopyridin-2-yl)methanol The following contents are mentioned in the article:

A new ruthenium-catalyzed direct and selective synthesis of semisatd. bicyclic pyrimidines, from ä¼?aminopyridyl alcs. and nitriles, has been demonstrated. The synthesis proceeds with an easily available catalyst system, broad substrate scope, excellent functional tolerance, and no need for high pressure H2 gas. Control experiments indicate that the reaction proceeds via successive dehydrogenative annulation and transfer hydrogenation of the less electrophilic pyridyl nucleus, and the d. functional theory (DFT) study reveals the origin of such a unique selectivity. This study involved multiple reactions and reactants, such as (3-Aminopyridin-2-yl)methanol (cas: 52378-63-9Quality Control of (3-Aminopyridin-2-yl)methanol).

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Quality Control of (3-Aminopyridin-2-yl)methanol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xiong, Biao et al. published their research in Organic Letters in 2015 | CAS: 52378-63-9

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six èŸ?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Name: (3-Aminopyridin-2-yl)methanol

Ruthenium-Catalyzed Straightforward Synthesis of 1,2,3,4-Tetrahydronaphthyridines via Selective Transfer Hydrogenation of Pyridyl Ring with Alcohols was written by Xiong, Biao;Li, Ya;Lv, Wan;Tan, Zhenda;Jiang, Huanfeng;Zhang, Min. And the article was included in Organic Letters in 2015.Name: (3-Aminopyridin-2-yl)methanol The following contents are mentioned in the article:

Through a ruthenium-catalyzed selective hydrogen transfer coupling reaction, a novel straightforward synthesis of 1,2,3,4-tetrahydronaphthyridines e. g., I, from o-aminopyridyl methanols and alcs. has been developed. The synthetic protocol proceeds in an atom- and step-economic fashion together with the advantages of operational simplicity, broad substrate scope, production of water as the only byproduct, and no need for external reducing reagents such as high pressure H2 gas, offering a highly practical approach for accessing this type of structurally unique products. This study involved multiple reactions and reactants, such as (3-Aminopyridin-2-yl)methanol (cas: 52378-63-9Name: (3-Aminopyridin-2-yl)methanol).

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six èŸ?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Name: (3-Aminopyridin-2-yl)methanol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xiong, Biao et al. published their research in Organic Letters in 2015 | CAS: 52378-63-9

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six èŸ?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Name: (3-Aminopyridin-2-yl)methanol

Ruthenium-Catalyzed Straightforward Synthesis of 1,2,3,4-Tetrahydronaphthyridines via Selective Transfer Hydrogenation of Pyridyl Ring with Alcohols was written by Xiong, Biao;Li, Ya;Lv, Wan;Tan, Zhenda;Jiang, Huanfeng;Zhang, Min. And the article was included in Organic Letters in 2015.Name: (3-Aminopyridin-2-yl)methanol The following contents are mentioned in the article:

Through a ruthenium-catalyzed selective hydrogen transfer coupling reaction, a novel straightforward synthesis of 1,2,3,4-tetrahydronaphthyridines e. g., I, from o-aminopyridyl methanols and alcs. has been developed. The synthetic protocol proceeds in an atom- and step-economic fashion together with the advantages of operational simplicity, broad substrate scope, production of water as the only byproduct, and no need for external reducing reagents such as high pressure H2 gas, offering a highly practical approach for accessing this type of structurally unique products. This study involved multiple reactions and reactants, such as (3-Aminopyridin-2-yl)methanol (cas: 52378-63-9Name: (3-Aminopyridin-2-yl)methanol).

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six èŸ?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Name: (3-Aminopyridin-2-yl)methanol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xiong, Biao et al. published their research in Organic Letters in 2017 | CAS: 52378-63-9

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Quality Control of (3-Aminopyridin-2-yl)methanol

Ruthenium-Catalyzed Direct Synthesis of Semisaturated Bicyclic Pyrimidines via Selective Transfer Hydrogenation was written by Xiong, Biao;Jiang, Jingxing;Zhang, Shudi;Jiang, Huanfeng;Ke, Zhuofeng;Zhang, Min. And the article was included in Organic Letters in 2017.Quality Control of (3-Aminopyridin-2-yl)methanol The following contents are mentioned in the article:

A new ruthenium-catalyzed direct and selective synthesis of semisatd. bicyclic pyrimidines, from 伪-aminopyridyl alcs. and nitriles, has been demonstrated. The synthesis proceeds with an easily available catalyst system, broad substrate scope, excellent functional tolerance, and no need for high pressure H2 gas. Control experiments indicate that the reaction proceeds via successive dehydrogenative annulation and transfer hydrogenation of the less electrophilic pyridyl nucleus, and the d. functional theory (DFT) study reveals the origin of such a unique selectivity. This study involved multiple reactions and reactants, such as (3-Aminopyridin-2-yl)methanol (cas: 52378-63-9Quality Control of (3-Aminopyridin-2-yl)methanol).

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Quality Control of (3-Aminopyridin-2-yl)methanol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xiong, Biao et al. published their research in Organic Letters in 2015 | CAS: 52378-63-9

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six 蟺 electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Name: (3-Aminopyridin-2-yl)methanol

Ruthenium-Catalyzed Straightforward Synthesis of 1,2,3,4-Tetrahydronaphthyridines via Selective Transfer Hydrogenation of Pyridyl Ring with Alcohols was written by Xiong, Biao;Li, Ya;Lv, Wan;Tan, Zhenda;Jiang, Huanfeng;Zhang, Min. And the article was included in Organic Letters in 2015.Name: (3-Aminopyridin-2-yl)methanol The following contents are mentioned in the article:

Through a ruthenium-catalyzed selective hydrogen transfer coupling reaction, a novel straightforward synthesis of 1,2,3,4-tetrahydronaphthyridines e. g., I, from o-aminopyridyl methanols and alcs. has been developed. The synthetic protocol proceeds in an atom- and step-economic fashion together with the advantages of operational simplicity, broad substrate scope, production of water as the only byproduct, and no need for external reducing reagents such as high pressure H2 gas, offering a highly practical approach for accessing this type of structurally unique products. This study involved multiple reactions and reactants, such as (3-Aminopyridin-2-yl)methanol (cas: 52378-63-9Name: (3-Aminopyridin-2-yl)methanol).

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six 蟺 electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Name: (3-Aminopyridin-2-yl)methanol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tan, Zhenda et al. published their research in ACS Catalysis in 2020 | CAS: 52378-63-9

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ路mol鈭? in pyridine vs. 150 kJ路mol鈭? in benzene). Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Category: pyridine-derivatives

Catalytic Conversion of N-Heteroaromatics to Functionalized Arylamines by Merging Hydrogen Transfer and Selective Coupling was written by Tan, Zhenda;Ci, Chenggang;Yang, Jian;Wu, Yang;Cao, Liang;Jiang, Huanfeng;Zhang, Min. And the article was included in ACS Catalysis in 2020.Category: pyridine-derivatives The following contents are mentioned in the article:

A ruthenium-catalyzed deconstruction of N-heteroaromatics to functionalized arylamines with 2-aminoaryl methanols via hydrogen transfer and selective coupling was reported. The reaction was achieved via sequential functionalization of the 尾 and 伪-sites of the initially formed N-heteroarenium salts followed by a C-N cleavage, proceeding with the striking features of broad substrate scope, excellent functional groups tolerance, high chemoselectivity and atom-efficiency, and applicable for streamline synthesis of some biomedical mols. The strategy utilized will pave the avenues for further development of catalytic transformations of inert organo-systems to functional frameworks. This study involved multiple reactions and reactants, such as (3-Aminopyridin-2-yl)methanol (cas: 52378-63-9Category: pyridine-derivatives).

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ路mol鈭? in pyridine vs. 150 kJ路mol鈭? in benzene). Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xie, Feng et al. published their research in ACS Catalysis in 2018 | CAS: 52378-63-9

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six 蟺 electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Computed Properties of C6H8N2O

MOF-Derived Nanocobalt for Oxidative Functionalization of Cyclic Amines to Quinazolinones with 2-Aminoarylmethanols was written by Xie, Feng;Chen, Qing-Hua;Xie, Rong;Jiang, Huan-Feng;Zhang, Min. And the article was included in ACS Catalysis in 2018.Computed Properties of C6H8N2O The following contents are mentioned in the article:

By employing a MOF-templated method, we have developed a highly dispersed and ultralow loading cobalt nanocatalyst, which has been applied in the oxidative functionalization of easily available cyclic amines with 2-aminoarylmethanols to ring-fused quinazolinones, the core structures of numerous valuable products. The developed catalytic transformation proceeds with the merits of broad substrate scope, good functional group tolerance and chemoselectivity, high step- and atom-efficiency, and use of the naturally abundant Co/O2 system, which offers a practical way for the preparation of quinazolinones with structural diversity. The work presented has built an important basis for direct conversion of cyclic amine motifs into functional frameworks. This study involved multiple reactions and reactants, such as (3-Aminopyridin-2-yl)methanol (cas: 52378-63-9Computed Properties of C6H8N2O).

(3-Aminopyridin-2-yl)methanol (cas: 52378-63-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six 蟺 electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Computed Properties of C6H8N2O

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem