Category: 5315-25-3

Pyridine is colorless, but older or impure samples can appear yellow. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Product Details of C6H6BrN.

Waters, Jessica E.;Hanf, Schirin;Rincon-Nocito, Marina;Bond, Andrew D.;Garcia-Rodriguez, Raul;Wright, Dominic S.;Colebatch, Annie L. research published 《 Synthesis and coordination behavior of aluminate-based quinolyl ligands》, the research content is summarized as follows. Lithium tris-quinolinylaluminate complexes were prepared by transmetalation of quinolinyllithium compounds with EtAlCl₂; the electronic and steric effects of substitution of 2-quinolinyl groups for remote 8-quinolinyl groups were evaluated by single-crystal x-ray diffraction anal. and theor. calculations The effects of moving the donor N-atom from the 2-position in lithium (2-pyridyl)- and (2-quinolyl)aluminates to the more remote position in (8-quinolyl)aluminates have been investigated by solid-state structural and DFT computational studies of the new complexes [{EtAl(2-qy)₃}Li(μ-X)Li(THF)₃] (X = Cl/Br 62:38) [(1)Li(μ-X)Li(THF)₃], [{(EtAl(2-qy)₃)Li}₂(μ-Br)]^–Li(THF)₄⁺ [{1Li}₂(μ-Br)]^–Li(THF)₄⁺, [{EtAl(2-Me-8-qy)₃}Li] [(2)Li], [{Me₂Al(2-Me-8-qy)₂}Li(THF)] [(3a)Li(THF)], [{Me₂Al(6-Me-2-py)₂}Li(THF)₂] [(4)Li(THF)₂] and [{{EtAl(2-Me-8-qy)₂}₂O}(Li₂THF)] (5). Increasing the remoteness of the donor N-atom from the bridgehead results in large differences in the coordination of the Li⁺ cations by the (8-quinolyl)aluminate anions compared to 2-quinolyl or 2-pyridyl counterparts. The results are of potential interest in understanding how the coordination sites of ligands of this type can be tuned for the coordination requirements of specific metal centers.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Product Details of C6H6BrN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Computed Properties of 5315-25-3.

Wang, Yi-Dong;Liu, Jin-Kui;Yang, Xue-Jie;Gong, Jun-Fang;Song, Mao-Ping research published 《 Chiral (Pyridine)-(Imidazoline) NCN’ Pincer Palladium(II) Complexes: Convenient Synthesis via C-H Activation and Characterization》, the research content is summarized as follows. A series of aryl-based chiral NCN’ pincer palladium(II) complexes 4a–k were synthesized via C-H activation of the (pyridyl)-(imidazolinyl)benzene ligands, which proceeded smoothly with PdCl₂ as the palladium source in the presence of Et₃N or NaHCO₃ base in toluene under reflux. All of the complexes have been characterized by elemental anal. and ¹H and ¹³C{¹H} NMR spectroscopy. In addition, the mol. structures of complexes 4a, 4c, and 4f have been determined by x-ray single-crystal diffraction anal. The obtained chiral Pd pincers were applied to catalytic asym. reactions of acrylonitrile and dichloroacetonitrile with sulfonimines. With a catalyst loading of 5 mol % and the assistance of AgOAc, these complexes acted as active but moderately stereoselective catalysts for the aforementioned reactions.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Computed Properties of 5315-25-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. COA of Formula: C6H6BrN.

Tian, Wan-Fa;He, Ke-Han;Li, Na;Fen;Liu;Mai, Xi;Feng, Li-Hua;He, Yong-Qin research published 《 Transition-Metal-Free Coupling Reactions: PPh₃-Promoted Sonogashira-Type Cross-Couplings of Heteroaryl Halides with Terminal Alkynes》, the research content is summarized as follows. Synthesis phenylethynyl heteroaryl I [Ar¹ = 2-pyridyl, 6-Me-3-pyridyl, 3-quinolyl, etc.; Ar² = Ph 2-FC₆H₄, 4-MeOC₆H₄, etc.] via Sonogashira-type cross-coupling reaction of heteroaryl halides with terminal alkynes under mild transition-metal-free conditions using PPh₃ and Cs₂CO₃/NEt₃ was reported, a wide range of functional groups was tolerated under optimized conditions. Furthermore, the protocol would be extended to the Suzuki-type cross-coupling of heteroaryl halides with phenylboronic acid, to gave the Ph heteroaryl II [Ar³ = 3-pyridyl, 5-pyrimidinyl, 3-quinolyl, etc.] in good to excellent yields. A test reaction on gram scale delivered the product in reasonably high yield and thus had the potential of promising applications in drug discovery and functional materials.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., COA of Formula: C6H6BrN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Computed Properties of 5315-25-3.

Togo, Takaya;Sohma, Youhei;Kuninobu, Yoichiro;Kanai, Motomu research published 《 Palladium-catalyzed C-H heteroarylation of 2,5-disubstituted imidazoles》, the research content is summarized as follows. A palladium-catalyzed C-H N-heteroarylation of N-protected-2,5-disubstituted imidazoles at the C4-position using N-heteroaryl halides as a coupling partner was developed. Intensive reaction condition screening led to identify fluorinated bathophenanthroline as the optimum ligand for the palladium catalyst. This reaction enhanced optimization of drug candidates by facilitating the synthesis of heterobiaryl compounds containing an imidazole ring.

Computed Properties of 5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Reference of 5315-25-3.

Tsybizova, Alexandra;Fritsche, Lukas;Gorbachev, Vladimir;Miloglyadova, Larisa;Chen, Peter research published 《 Cryogenic ion vibrational predissociation (CIVP) spectroscopy of a gas-phase molecular torsion balance to probe London dispersion forces in large molecules》, the research content is summarized as follows. We report a gas-phase mol. torsion balance that uses a conformational equilibrium to “weigh” London dispersion against a competing cation-π interaction, for which the readout is the shift in an N-H stretching frequency measured by cryogenic ion vibrational predissociation (CIVP) spectroscopy of electrosprayed pyridinium cations in a Fourier-transform ion cyclotron resonance trap. While frequency calculations with DFT, within the harmonic approximation, assist in the interpretation of the spectra, the observed complex spectrum most likely comes from a Fermi resonance of the N-H stretch with otherwise “dark” overtones of in-plane C-H wagging modes, as argued on the basis of comparison of the spectrum to those for a range of related cations with systematically varied substitution. An equilibrium in favor of the asym. conformer would suggest that the dispersion-corrected DFT calculations tested in this work appear to overestimate significantly the stability of the compact conformations favored by London dispersion in the gas phase, which would then pertain to the use of dispersion energy donors in the design of stereoselective reactions. (c) 2019 American Institute of Physics.

Reference of 5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The critical parameters of pyridine are pressure 6.70 MPa, temperature 620 K and volume 229 cm3·mol−1. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. In the temperature range 340–426 °C its vapor pressure p can be described with the Antoine equation.. COA of Formula: C6H6BrN.

Vanga, Mukundam;Lalancette, Roger A.;Jaekle, Frieder research published 《 Controlling the Optoelectronic Properties of Pyrene by Regioselective Lewis Base-Directed Electrophilic Aromatic Borylation》, the research content is summarized as follows. Pyreno-annelated azaboroles I (5, X = C₁₃H₂₇, R = Ph, Et) and azaborines II (6, Y = C₈H₁₇, R = Ph, Et) were prepared by stepwise borylation-Suzuki coupling of pyrene and examined for their photophys. properties. Given that pyrene represents one of the most versatile chromophores, the development of new selective routes for its functionalization and tuning of its emission properties is highly desirable. Pyrene-based BN Lewis pair (LP)-functionalized polycyclic aromatic hydrocarbons (PAHs) were prepared by regioselective Lewis base-directed electrophilic aromatic substitution. The requisite 1,6-dipyridylpyrene ligands were accessed by Suzuki-Miyaura cross-coupling of 1,6-bis(pinacolatoboryl)pyrenes with 2-bromopyridine derivatives Subsequent electrophilic borylation with BCl₃ in the presence of AlCl₃ and 2,6-di-tert-butylpyridine as a hindered base produced the dichloroborane complexes, which were then in situ reacted with di-Ph or di-Et zinc. The presence or absence of alkyl chains in the 3,8-positions of the pyrene moiety determined the position of the B-C bond formation (2,7 in the non-K region vs. 5,10 in the K region) and thereby also the size of the BN heterocycle (five- vs. six-membered). The impact of the regioisomeric borylation on the electrochem., photophys. and structural properties was investigated and the conclusions supported by theor. calculations The rapid synthesis of derivatives that are borylated in the K region also suggests strong potential for the development of pyrene derivatives that are otherwise difficult to access.

COA of Formula: C6H6BrN, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Safety of 2-Bromo-6-methylpyridine.

Wagener, Tobias;Lueckemeier, Lukas;Daniliuc, Constantin G.;Glorius, Frank research published 《 Interrupted pyridine hydrogenation: Asymmetric synthesis of δ-lactams》, the research content is summarized as follows. Metal-catalyzed hydrogenation is an effective method to transform readily available arenes into saturated motifs, however, current hydrogenation strategies are limited to the formation of C-H and N-H bonds. The stepwise addition of hydrogen yields reactive unsaturated intermediates that are rapidly reduced. In contrast, the interruption of complete hydrogenation by further functionalization of unsaturated intermediates offers great potential for increasing chem. complexity in a single reaction step. Overcoming the tenet of full reduction in arene hydrogenation has been seldom demonstrated. In this work the authors report the synthesis of sought-after, enantioenriched δ-lactams from oxazolidinone-substituted pyridines and water by an interrupted hydrogenation mechanism.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Safety of 2-Bromo-6-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Application In Synthesis of 5315-25-3.

Wang, Jinglan;Chen, Hongyun;Xu, Shengxian;Su, Qingzhi;Zhao, Feng;He, Haifeng research published 《 Highly effective luminescence stemmed from thermally activated delayed fluorescence (TADF) and phosphorescence for new four-coordinate copper(I) complexes containing N-heterocyclic carbene (NHC) ligands》, the research content is summarized as follows. The two four-coordinate N-heterocyclic carbene (NHC) copper(I) complexes, [Cu(Ph-BenIm-methylPy)(POP)]PF₆ (1), and [Cu(Ph-Im-methylPy)(POP)]PF₆ (2), Ph-BenIm-methylPy = 3-benzyl-1-(6-methyl-pyridin-2-yl)-1H-benzimidazolylidene, Ph-Im-methylPy = 3-benzyl-1-(6-methyl-pyridin-2-yl)-1H-imidazolylidene, POP = bis[2-(diphenylphosphino)phenyl] ether have been synthesized and characterized. Those complexes exhibit blue to green emission with very high quantum yields and long excited-state lifetimes. The exptl. results reveal that the origin of emissive state at room temperature occurs from the combination of TADF and phosphorescence in which phosphorescence predominates TADF, and the corresponding emissive mechanisms were discussed. To the best of our knowledge, the combined emissions with high quantum yield close to ca. 100% have not been previously reported in this library of the four-coordinate NHC-Cu(I) complexes.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Application In Synthesis of 5315-25-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. COA of Formula: C6H6BrN.

Sun, Lincong;Zhao, Yuyao;Liu, Bingxian;Chang, Junbiao;Li, Xingwei research published 《 Rhodium^III-catalyzed remote difunctionalization of arenes assisted by a relay directing group》, the research content is summarized as follows. Rhodium-catalyzed diverse tandem twofold C-H bond activation reactions of para-olefin-tethered arenes were realized, with unsaturated reagents such as internal alkynes, dioxazolones, and isocyanates being the coupling partner as well as a relay directing group which triggers cyclization of the para-olefin group under oxidative or redox-neutral conditions. The reaction proceeded via initial ortho-C-H activation assisted by a built-in directing group in the arene, and the ortho-incorporation of the unsaturated coupling partner simultaneously generated a relay directing group that allows sequential C-H activation at the meta-position and subsequent cyclization of the para-olefins. The overall reaction represents C-C or N-C difunctionalization of the arene with the generation of diverse 2,3-dihydrobenzofuran platforms, e.g., I. The catalytic system proceeded with good efficiency, simple reaction conditions, and broad substrate scope. The diverse transformations of the products demonstrated the synthetic utility of this tandem reaction.

COA of Formula: C6H6BrN, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. HPLC of Formula: 5315-25-3.

Sun, Maolin;Li, Jianchang;Liang, Chaoming;Shan, Chao;Shen, Xinyuan;Cheng, Ruihua;Ma, Yueyue;Ye, Jinxing research published 《 Practical and rapid construction of 2-pyridyl ketone library in continuous flow》, the research content is summarized as follows. Herein, a practical method for the rapid synthesis of 2-pyridyl ketone ArC(O)R [Ar = 2-pyridyl; R = Me, Ph, Bn, etc.] library in continuous flow was reported, in which the 2-lithiopyridine formed by Br/Li exchange reacts with com. available esters to obtain 2-pyridyl ketones ArC(O)R in a good yield at short reaction time. This protocol functions broadly on a variety of esters and had been applied to the synthesis of TGF-β type 1 receptor inhibitor LY580276 intermediate ArC(O)R [Ar = 6-methyl-2-pyridyl; R = (4-fluorophenyl)methyl] in an environmentally friendly method. It was rapid, reliable, and cost-efficient to afford diverse kinds of 2-pyridyl ketones ArC(O)R in the compound library.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., HPLC of Formula: 5315-25-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem