Category: 5632-81-5

Adding a certain compound to certain chemical reactions, such as: 5632-81-5, 2-Chloropyridine-3,5-diamine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 5632-81-5, blongs to pyridine-derivatives compound. COA of Formula: C5H6ClN3

REFERENCE EXAMPLE 18 Synthesis of ethyl 3-[(5-amino-6-chloropyridin-3-yl)amino]-2-(3-chloro-2,4,5-trifluorobenzoyl)acrylate To 1.4 g of ethyl 3-chloro-2,4,5-trifluorobenzoyl-acetate were added 1.5 g of acetic anhydride and 1.5 g of triethyl orthoformate, and the mixture was heated under reflux for 2 hours. The solvent was distilled off, and toluene was added to the residue for azeotropic distillation. 3 ml of chloroform was added to the half of the residue, and a solution of 360 mg of 3,5-diamino-2-chloropyridine in 3 ml ethanol was added dropwise to the mixture at room temperature and the mixture was stirred at room temperature for 30 minutes. The solvent was distilled off, and the residue was purified by column chromatography to obtain 200 mg of the title compound.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,5632-81-5, its application will become more common.

Reference:
Patent; Wakunaga Pharmaceuticals Co., Ltd.; US5998436; (1999); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 5632-81-5, 2-Chloropyridine-3,5-diamine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 5632-81-5, blongs to pyridine-derivatives compound. category: pyridine-derivatives

REFERENCE EXAMPLE 18 Synthesis of ethyl 3-[(5-amino-6-chloropyridin-3-yl)amino]-2-(3-chloro-2,4,5-trifluorobenzoyl)acrylate To 1.4 g of ethyl 3-chloro-2,4,5-trifluorobenzoyl-acetate were added 1.5 g of acetic anhydride and 1.5 g of triethyl orthoformate, and the mixture was heated under reflux for 2 hours. The solvent was distilled off, and toluene was added to the residue for azeotropic distillation. 3 ml of chloroform was added to the half of the residue, and a solution of 360 mg of 3,5-diamino-2-chloropyridine in 3 ml ethanol was added dropwise to the mixture at room temperature and the mixture was stirred at room temperature for 30 minutes. The solvent was distilled off, and the residue was purified by column chromatography to obtain 200 mg of the title compound.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,5632-81-5, its application will become more common.

Reference:
Patent; Wakunaga Pharmaceuticals Co., Ltd.; US5998436; (1999); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 5632-81-5, name is 2-Chloropyridine-3,5-diamine, molecular formula is C5H6ClN3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. category: pyridine-derivatives

80 ml of ethanol are placed in a 250-ml one-necked round-bottomed flask equipped with a calcium chloride guard tube, followed by addition, with stirring, of 4.11 g (18.1 mmol) of 2-(propan-2-yloxy)pyrazolo[l,5-a]pyridin-3-amine hydrochloride. 1.18 g (8.21 mmol) of 2-chloropyridine-3,5-diamine and 5.0 ml (29 mol) of N-ethyl-N-(propan-2-yl)propan-2-amine are added to this solution.The solution is then stirred at room temperature for 4 days. The black precipitate formed is isolated by filtration, washed with water and dried in a desiccator under vacuum at 30C in the presence of a desiccant, to constant weight. The compound is thus obtained in the form of a black powder.

With the rapid development of chemical substances, we look forward to future research findings about 5632-81-5.

Reference:
Patent; L’OREAL; FADLI, Aziz; BLAIS, Stephane; (70 pag.)WO2016/97198; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem