Category: 61548-52-5

The author of 《Carbonation of 3-pyridinols》 were Mutterer, F.; Weis, C. D.. And the article was published in Journal of Heterocyclic Chemistry in 1976. Application of 61548-52-5 The author mentioned the following in the article:

Heating I and II (R = H) with CO2 at 220° and 60 atms. gave the carboxylic acids I and II (R = CO2H). Heating I (R = CO2H) in NH3(l) gave III. In the experiment, the researchers used many compounds, for example, Methyl 3-hydroxy-6-methylpicolinate(cas: 61548-52-5Application of 61548-52-5)

Methyl 3-hydroxy-6-methylpicolinate(cas: 61548-52-5) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Application of 61548-52-5

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists》 was published in Bioorganic & Medicinal Chemistry Letters in 2012. These research results belong to Guerrero, Miguel; Urbano, Mariangela; Zhao, Jian; Crisp, Melissa; Chase, Peter; Hodder, Peter; Schaeffer, Marie-Therese; Brown, Steven; Rosen, Hugh; Roberts, Edward. Reference of Methyl 3-hydroxy-6-methylpicolinate The article mentions the following:

High affinity and selective small mol. agonists of the S1P4 receptor (S1P4-R) may have significant therapeutic utility in diverse disease areas including autoimmune diseases, viral infections and thrombocytopenia. A high-throughput screening (HTS) of the Mol. Libraries-Small Mol. Repository library identified 3-(2-(2,4-dichlorophenoxy)ethoxy)-6-methyl-2-nitropyridine (I) as a moderately potent and selective S1P4-R hit agonist. Design, synthesis and systematic structure-activity relationships study of the HTS-derived hit led to the development of novel potent S1P4-R agonists exquisitely selective over the remaining S1P1-3,5-Rs family members. Remarkably, the mols. herein reported provide novel pharmacol. tools to decipher the biol. function and assess the therapeutic utility of the S1P4-R. In the part of experimental materials, we found many familiar compounds, such as Methyl 3-hydroxy-6-methylpicolinate(cas: 61548-52-5Reference of Methyl 3-hydroxy-6-methylpicolinate)

Methyl 3-hydroxy-6-methylpicolinate(cas: 61548-52-5) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Reference of Methyl 3-hydroxy-6-methylpicolinate

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem