Category: 626-05-1

《Metal-Ligand Cooperativity via Exchange Coupling Promotes Iron- Catalyzed Electrochemical CO2 Reduction at Low Overpotentials》 was written by Derrick, Jeffrey S.; Loipersberger, Matthias; Chatterjee, Ruchira; Iovan, Diana A.; Smith, Peter T.; Chakarawet, Khetpakorn; Yano, Junko; Long, Jeffrey R.; Head-Gordon, Martin; Chang, Christopher J.. Quality Control of 2,6-Dibromopyridine And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:

Biol. and heterogeneous catalysts for the electrochem. CO2 reduction reaction (CO2RR) often exhibit a high degree of electronic delocalization that serves to minimize overpotential and maximize selectivity over the hydrogen evolution reaction (HER). Here, we report a mol. iron(II) system that captures this design concept in a homogeneous setting through the use of a redox non-innocent terpyridine-based pentapyridine ligand (tpyPY2Me). As a result of strong metal-ligand exchange coupling between the Fe(II) center and ligand, [Fe(tpyPY2Me)]2+ exhibits redox behavior at potentials 640 mV more pos. than the isostructural [Zn(tpyPY2Me)]2+ analog containing the redox-inactive Zn(II) ion. This shift in redox potential is attributed to the requirement for both an open-shell metal ion and a redox non-innocent ligand. The metal-ligand cooperativity in [Fe(tpyPY2Me)]2+ drives the electrochem. reduction of CO2 to CO at low overpotentials with high selectivity for CO2RR (>90%) and turnover frequencies of 100 000 s-1 with no degradation over 20 h. The decrease in the thermodn. barrier engendered by this coupling also enables homogeneous CO2 reduction catalysis in water without compromising selectivity or rates. Synthesis of the two-electron reduction product, [Fe(tpyPY2Me)]0, and characterization by X-ray crystallog., Mossbauer spectroscopy, X-ray absorption spectroscopy (XAS), variable temperature NMR, and d. functional theory (DFT) calculations, support assignment of an open-shell singlet electronic structure that maintains a formal Fe(II) oxidation state with a doubly reduced ligand system. This work provides a starting point for the design of systems that exploit metal-ligand cooperativity for electrocatalysis where the electrochem. potential of redox non-innocent ligands can be tuned through secondary metal-dependent interactions. In the experiment, the researchers used many compounds, for example, 2,6-Dibromopyridine(cas: 626-05-1Quality Control of 2,6-Dibromopyridine)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Quality Control of 2,6-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lisboa, Lynn S.; Riisom, Mie; Vasdev, Roan A. S.; Jamieson, Stephen M. F.; Wright, L. James; Hartinger, Christian G.; Crowley, James D. published an article in 2021. The article was titled 《Cavity-containing [Fe2L3] 4+ helicates: an examination of host-guest chemistry and cytotoxicity》, and you may find the article in Frontiers in Chemistry (Lausanne, Switzerland).Electric Literature of C5H3Br2N The information in the text is summarized as follows:

Two new di(2,2′-bipyridine) ligands, 2,6-bis([2,2′-bipyridin]-5-ylethynyl)pyridine (L1) and bis(4-([2,2′-bipyridin]-5-ylethynyl)phenyl)methane (L2) were synthesized and used to generate two metallosupramol. [Fe2(L)3](BF4)4 cylinders. The ligands and cylinders were characterized using elemental anal., electrospray ionization mass spectrometry, UV-vis, 1H-, 13C and DOSY NMR (NMR) spectroscopies. The mol. structures of the [Fe2(L)3](BF4)4 cylinders were confirmed using X-ray crystallog. Both the [Fe2(L1)3](BF4)4 and [Fe2(L2)3](BF4)4 complexes crystallized as racemic (rac) mixtures of the δδ (P) and λλ (M) helicates. However, 1H NMR spectra showed that in solution the larger [Fe2(L2)3](BF4)4 was a mixture of the rac δδ/λλ and meso-δλ isomers. The host-guest chem. of the helicates, which both feature a central cavity, was examined with several small drug mols. However, none of the potential guests were found to bind within the helicates. In vitro cytotoxicity assays demonstrated that both helicates were active against four cancer cell lines. The smaller [Fe2(L1)3](BF4)4 system displayed low μM activity against the HCT116 (IC50 = 7.1 ± 0.5 μM) and NCI-H460 (IC50 = 4.9 ± 0.4 μM) cancer cells. While the antiproliferative effects against all the cell lines examined were less than the well-known anticancer drug cisplatin, their modes of action would be expected to be very different. The experimental part of the paper was very detailed, including the reaction process of 2,6-Dibromopyridine(cas: 626-05-1Electric Literature of C5H3Br2N)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Electric Literature of C5H3Br2N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Rational Design of Multi-Stimuli-Responsive Scaffolds: Synthesis of Luminescent Oligo(ethynylpyridine)-Containing Alkynylplatinum(II) Polypyridine Foldamers Stabilized by Pt···Pt Interactions》 were Chan, Michael Ho-Yeung; Leung, Sammual Yu-Lut; Yam, Vivian Wing-Wah. And the article was published in Journal of the American Chemical Society in 2019. Name: 2,6-Dibromopyridine The author mentioned the following in the article:

A series of oligo(ethynylpyridine)-containing alkynylplatinum(II) terpyridine/bzimpy (bzimpy = 2,6-bis(N-alkylbenzimidazol-2′-yl)pyridine) metallofoldamers [L3Pt(CC-1,3-Ar)nCCPtL3] (L3 = tpy, bzimpy; Ar = m-phenylene, 2,6-pyridinediyl) has been designed and synthesized to investigate the potential applications of metallofoldamers imparted by the rich spectroscopic responses of Pt···Pt interactions. Apart from the control of the folding/unfolding processes by solvent compositions and temperatures, this class of metallofoldamers has also been found to exhibit reversible folding/unfolding behaviors mediated by the addition of acids/bases due to the incorporation of the acid-sensitive oligo(ethynylpyridine) derivatives More importantly, the intramol. Pt···Pt interaction has been found to play a crucial role in governing the folded state conformation. The conformation of this class of metallofoldamers has been investigated by 2D ROESY NMR, electronic absorption, and emission spectroscopy, which provide further insights into the rational mol. design and multidimensional control of metallofoldamers upon the application of various external stimuli, leading to the preparation of multi-stimuli-responsive materials for potential applications in material sciences. In addition to this study using 2,6-Dibromopyridine, there are many other studies that have used 2,6-Dibromopyridine(cas: 626-05-1Name: 2,6-Dibromopyridine) was used in this study.

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Name: 2,6-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Name: 2,6-DibromopyridineIn 2020 ,《A novel approach for rhodium(III)-catalyzed C-H functionalization of 2,2′-bipyridine derivatives with alkynes: a significant substituent effect》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Wu, Shaonan; Wang, Zhuo; Bao, Yinwei; Chen, Chen; Liu, Kun; Zhu, Bolin. The article conveys some information:

The authors described a novel approach for the C-H functionalization of 2,2′-bipyridine derivatives with alkynes. DFT calculations and exptl. data showed a significant substituent effect at the 6-position of 2,2′-bipyridine, which weakened the adjacent N-Rh bond and provided the possibility of subsequent rollover cyclometalation, C-H activation, and functionalization.2,6-Dibromopyridine(cas: 626-05-1Name: 2,6-Dibromopyridine) was used in this study.

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Name: 2,6-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《A conjugated microporous polymer as a recyclable heterogeneous ligand for highly efficient regioselective hydrosilylation of allenes》 was written by Jiang, Ya-Nan; Zeng, Jia-Hao; Yang, Ying; Liu, Zhi-Kai; Chen, Jun-Jia; Li, Ding-Chang; Chen, Li; Zhan, Zhuang-Ping. Electric Literature of C5H3Br2N And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:

Pyridines containing adjacent CC bonds were utilized as ligand units and integrated into the skeleton of conjugated microporous polymers. The resultant Pd-CMP-1 was first applied as a highly efficient heterogeneous catalytic system for Pd-catalyzed allene hydrosilylation towards a wide range of allenes to produce branched allylsilanes with high regioselectivity. The ligand units of the polymer, along with the confinement effect of the porous structure, jointly regulated the regioselectivity. The parts-per-million (ppm) levels of Pd, coordinated with the recyclable heterogeneous ligand, show promise for industrial applications. This work opens a new front of using CMP as an intriguing platform for developing highly efficient catalysts to control the regioselectivities in allene hydrosilylation. The results came from multiple reactions, including the reaction of 2,6-Dibromopyridine(cas: 626-05-1Electric Literature of C5H3Br2N)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Electric Literature of C5H3Br2N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lauzon, Samuel; Ollevier, Thierry published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《2,2′-Bipyridine-α,α’-trifluoromethyl-diol ligand: Synthesis and application in the asymmetric Et2Zn alkylation of aldehydes》.Synthetic Route of C5H3Br2N The article contains the following contents:

A chiral 2,2′-bipyridine ligand I, bearing α,α’-trifluoromethyl-alcs. at the 6,6′-positions, was designed in five steps affording either the R,R/S,S enantiomer with excellent stereoselectivities, i.e., 97% de, >99% ee and >99.5% de, >99.5% ee, resp. The key step for reaching high levels of stereoselectivity was demonstrated to be the resolution of the α-CF3-alc. using (S)-ibuprofen as the resolving agent. An initial application for the 2,2′-bipyridine-α,α’-CF3-diol ligand was highlighted in the Zn(II)-catalyzed asym. ethylation reaction of aromatic, heteroaromatic, and aliphatic aldehydes RCHO (R = 4-chlophenyl, thiophen-2-yl, Pr, etc.). Synergistic electron deficiency and steric hindrance properties of the newly developed ligand afforded the corresponding alcs. in good to excellent yields (up to 99%) and enantioselectivities (up to 95% ee). In the part of experimental materials, we found many familiar compounds, such as 2,6-Dibromopyridine(cas: 626-05-1Synthetic Route of C5H3Br2N)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Synthetic Route of C5H3Br2N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bosch, Eric; Bowling, Nathan P.; Oburn, Shalisa M. published their research in Acta Crystallographica, Section C: Structural Chemistry in 2021. The article was titled 《Conformational control through co-operative nonconventional C-H···N hydrogen bonds》.Safety of 2,6-Dibromopyridine The article contains the following contents:

We report the design, synthesis, and crystal structure of a conjugated aryleneethynyl mol., 2-(2-{4,5-dimethoxy-2-[2-(2,3,4-trifluorophenyl)ethynyl]phenyl}ethynyl)-6-[2-(pyridin-2-yl)ethynyl]pyridine, C30H17F3N2O2, that adopts a planar rhombus conformation in the solid state. The mol. crystallizes in the space group P [inline formula omitted] , with Z = 2, and features two intramol. sp2-C-H···N hydrogen bonds that co-operatively hold the arylethynyl mol. in a rhombus conformation. The H atoms are activated towards hydrogen bonding since they are situated on a trifluorophenyl ring and the H···N distances are 2.470 (16) and 2.646 (16) Å, with C-H···N angles of 161.7 (2) and 164.7 (2)°, resp. Mol. electrostatic potential calculations support the formation of C-H···N hydrogen bonds to the trifluorophenyl moiety. Hirshfeld surface anal. identifies a self-complementary C-H···O dimeric interaction between adjacent 1,2-dimethoxybenzene segments that is shown to be common in structures containing that moiety. After reading the article, we found that the author used 2,6-Dibromopyridine(cas: 626-05-1Safety of 2,6-Dibromopyridine)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Safety of 2,6-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dierks, Philipp; Kruse, Ayla; Bokareva, Olga S.; Al-Marri, Mohammed J.; Kalmbach, Jens; Baltrun, Marc; Neuba, Adam; Schoch, Roland; Hohloch, Stephan; Heinze, Katja; Seitz, Michael; Kuehn, Oliver; Lochbrunner, Stefan; Bauer, Matthias published an article in 2021. The article was titled 《Distinct photodynamics of κ-N and κ-C pseudoisomeric iron(II) complexes》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Quality Control of 2,6-Dibromopyridine The information in the text is summarized as follows:

Two closely related FeII complexes with 2,6-bis(1-ethyl-1H-1,2,3-triazol-4yl)pyridine and 2,6-bis(1,2,3-triazol-5-ylidene)pyridine ligands are presented to gain new insights into the photophysics of bis(tridentate) iron(II) complexes. The [Fe(NN̂N̂)2]2+ pseudoisomer sensitizes singlet oxygen through a MC state with nanosecond lifetime after MLCT excitation, while the bis(tridentate) [Fe(CN̂Ĉ)2]2+ pseudoisomer possesses a similar 3MLCT lifetime as the tris(bidentate) [Fe(CĈ)2(NN̂)]2+ complexes with four mesoionic carbenes. In the experimental materials used by the author, we found 2,6-Dibromopyridine(cas: 626-05-1Quality Control of 2,6-Dibromopyridine)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Quality Control of 2,6-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Recommanded Product: 2,6-DibromopyridineIn 2020 ,《Spin transition in a ferrous chloride complex supported by a pentapyridine ligand》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Boniolo, Manuel; Shylin, Sergii I.; Chernev, Petko; Cheah, Mun Hon; Heizmann, Philipp A.; Huang, Ping; Salhi, Nessima; Hossain, Kamal; Thapper, Anders; Lundberg, Marcus; Messinger, Johannes. The article conveys some information:

Ferrous chloride complexes [FeIILxCl] commonly attain a high-spin state independently of the supporting ligand(s) and temperature Herein, authors present the first report of a complete spin crossover with T1/2 = 80 K in [FeII(Py5OH)Cl]+ (Py5OH = pyridine-2,6-diylbis[di(pyridin-2-yl)methanol]). Both spin forms of the complex are analyzed by x-ray spectroscopy and DFT calculations2,6-Dibromopyridine(cas: 626-05-1Recommanded Product: 2,6-Dibromopyridine) was used in this study.

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Recommanded Product: 2,6-Dibromopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Structures and photophysical properties of two luminescent bipyridine compounds: 2′,6′-difluoro-6-[3-(pyridin-2-yloxy)phenyl]-2,3′-bipyridine and 2′,6′-dimethoxy-6-[3-(pyridin-2-yloxy)phenyl]-2,3′-bipyridine》 was published in Acta Crystallographica, Section C: Structural Chemistry in 2020. These research results belong to Park, Ki-Min; Yang, Kiyull; Moon, Suk-Hee; Kang, Youngjin. Related Products of 626-05-1 The article mentions the following:

The title compounds, C21H13F2N3O (1) and C23H19N3O3 (2), have been synthesized by typical cross-coupling reactions. Both compounds have been characterized by single-crystal X-ray diffraction. Bipyridine 1 exhibits a fully extended structure in which the terminal pyridine rings are oriented away from each other, while bipyridine 2 displays a bent structure in which terminal pyridine rings are oriented in the same direction. Several intermol. interactions lead to the formation of two- and three-dimensional supramol. networks in the crystal structures of 1 and 2, resp. Compound 1 bears fluorine substituents and emits a strong fluorescence with λmax = 325 nm, while methoxy-substituted compound 2 displays red-shifted emissions with λmax = 366 nm. The emissions observed in both compounds originate from phenyl- and 2,3′-bipyridine-based π-π* transitions, according to theor. calculations Both compounds have high triplet energies (T1) ranging from 2.64 to 2.65 eV, which makes them potential host materials in organic light-emitting diodes (OLEDs). In the experimental materials used by the author, we found 2,6-Dibromopyridine(cas: 626-05-1Related Products of 626-05-1)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Related Products of 626-05-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem