Category: 626-64-2

Luminescent lanthanides complexes with mesogenic pyridone ligands: Emission and liquid crystals properties was written by Chiriac, Laura F.;Ilis, Monica;Circu, Viorel. And the article was included in Polyhedron in 2020.Recommanded Product: 626-64-2 This article mentions the following:

In this work, a systematic investigation of the influence of N-alkylated 4-pyridone ligands containing one cyanobiphenyl mesogenic group linked via a spacer with variable length (6, 8, 9 or 10 methylene groups) on the liquid crystalline properties and luminescence properties of the resulting lanthanide complexes with Eu(III), Sm(III) and Tb(III). The chem. structures of the new products were determined by ¹H and ¹³C NMR spectroscopy, as well as elemental anal. and IR spectroscopy. The lanthanide ions are 9-coordinate and surrounded by three pyridone ligands and three bidentate nitrate ions. The thermal behavior of the new products was analyzed by differential scanning calorimetry (DSC) and thermogravimetrical anal. (TG). The nature of the liquid crystalline phase was confirmed by polarizing optical microscopy (POM) and powder x-ray diffraction (XRD) studies. All complexes remain in the glassy state at room temperature while at higher temperature these materials display a SmA phase. Higher clearing temperatures were recorded for longer spacers. The emission spectra show characteristic emission bands for each lanthanide ion. The emission of the new complexes measured as a function of temperature decreases noticeably upon the increase of temperature and this process is reversible on cooling. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Recommanded Product: 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Recommanded Product: 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Taxonomic significance and antitumor activity of alkaloids from Clausena lansium Lour. Skeels (Rutaceae) was written by Peng, Wen-Wen;Fu, Xiao-Xiang;Xiong, Zhong-Hua;Wu, Hong-Liang;Chang, Jing-Wen;Huo, Guang-Hua;Li, Bao-Tong. And the article was included in Biochemical Systematics and Ecology in 2020.Name: Pyridin-4-ol This article mentions the following:

Phytochem. anal. of isolates from the aerial parts of Clausena lansium Lour. Skeels (Rutaceae) led to the identification of 14 alkaloids, including two indole alkaloids (1 and 2), one quinoline alkaloid (3), two pyridine alkaloids (4 and 5), four carbazole alkaloids (6-9) and five amides alkaloids (10-14). The phytochem. structures of the alkaloids were established by means of NMR and MS spectral analyses. Compounds (4, 5, 14) were three new natural products, while 1-3 and 10 were firstly reported from the genus Clausena and 8 and 9 were isolated from this species for the first time. The chemotaxonomic significance of these isolated alkaloids has also been discussed. All the isolated alkaloids were tested for their cytotoxic activity against Hela cancer cell line. Among them, four carbazole alkaloids 6-9 exhibited weak cytotoxicity with IC₅₀ values ranging from 69.31 to 138.32μM. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Name: Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Name: Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Graphene Oxide as a Carbocatalyst for Sustainable ipso-Hydroxylation of Arylboronic Acids: A Simple and Straightforward Strategy To Access Phenols was written by Karthik, Murugan;Suresh, Palaniswamy. And the article was included in ACS Sustainable Chemistry & Engineering in 2019.Safety of Pyridin-4-ol This article mentions the following:

A metal-free and straightforward protocol for the synthesis of phenols from aryl and heteroaryl boronic acids has been demonstrated using graphene oxide as a carbocatalyst. This sustainable ipso-hydroxylation takes place under mild conditions using aqueous H₂O₂ as an oxidant in a water medium in a short time under organocatalytic and base-free conditions. The control experiments reveal that the presence of carboxyl groups promotes ipso-hydroxylation. The developed methodol. offers GO as a benign solid-acid catalyst with good sustainability which can be reused several times without significant loss in its catalytic activities; this was proven by the Fourier transform IR and powder X-ray diffraction studies of the reused catalyst. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Safety of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Safety of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Metabolomics analysis of freeze-thaw tolerance enhancement mechanism of ε-poly-L-lysine on industrial yeast was written by Lu, Lu;Zhu, Ke-Xue;Yang, Zhen;Guo, Xiao-Na;Xing, Jun-Jie. And the article was included in Food Chemistry in 2022.COA of Formula: C5H5NO This article mentions the following:

Antimicrobial polycationic peptide ε-poly-L-lysine (ε-PL) enhanced the freeze-thaw tolerance of industrial yeast; the enhancement mechanism of ε-PL on yeast was studied. The results showed that a ε-PL coating was observed in ε-PL-treated yeast. After 4 times of freeze-thaw, the cell viability, glycerol content, and CO2 production of 0.6 mg/mL ε-PL-treated yeast were higher than those of untreated yeast, specifically, the cell viability of ε-PL-treated yeast was 87.6%, and that of untreated yeast was 68.5%. Metabolomic results showed that the enhancement mechanism of ε-PL on yeast was related to the promotion of cell membrane-related fatty acid synthesis pathways before freeze-thaw treatment, and the promotion of biosynthesis and glycerophospholipid metabolism pathways after freeze-thaw. Furthermore, ε-PL induced inhibition of the tricarboxylic acid cycle, resulting in a longer stationary phase at the beginning of the freeze-thaw and ultimately providing a higher level of freeze-thaw stress tolerance than untreated yeast. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2COA of Formula: C5H5NO).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.COA of Formula: C5H5NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A thermochemical computational study on hydroxyquinolines and their azulene analogues was written by Meshhal, Moyassar M.;El-Demerdash, Safinaz H.;El-Nahas, Ahmed M.. And the article was included in Journal of Molecular Structure in 2019.Related Products of 626-64-2 This article mentions the following:

Ab initio CBS-QB3 method has been used to determine gas-phase enthalpies of formation for 34 compounds including a number of hydroxyquinoline isomers, the corresponding azulene analogs and their parent systems. The mean absolute deviation of 4.43 kJ/mol reveals good agreement between our results and the available exptl. data. Relative thermodn. stabilities of hydroxyquinoline isomers and related analogs were discussed and several isomerization reactions enthalpies were derived. The same level of theory has also been utilized to calculate adiabatic ionization energies and electron affinities for the mols. with known exptl. values and the agreement between theory and experiment was found to be within 8 kJ/mol. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Related Products of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Related Products of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

4-Hydroxy Pyridinium Triflate@SiO₂ Nanoparticles as a Novel Efficient Catalyst for Fries Rearrangement of Aryl Esters with High Selectivity was written by Ghalehbandi, Shermineh Sadat;Ghazanfari, Dadkhoda;Ahmadi, Sayed Ali;Sheikhhosseini, Enayatollah. And the article was included in Current Organic Synthesis in 2020.SDS of cas: 626-64-2 This article mentions the following:

A simple, fast and new method for the Fries rearrangement of aryl esters was developed. 4-Hydroxy pyridinium triflate functionalized silica was a very efficient, reusable and economically available catalyst for the Fries rearrangement in solvent-free condition and under microwave irradiation Also, a notable selectivity was observed in the presence of 4-hydroxy pyridinium triflate functionalized silica. Selectivity, shorter reaction time, high yield and easy work-up are advantages of this synthetic method. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2SDS of cas: 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. SDS of cas: 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Design, synthesis and antitumor activities of thiazole-containing mitochondrial targeting agents was written by Zhang, Dongdong;Hu, Yixin;Hao, Zhiqiang;Zhang, Yang;Luo, Shuhua;Dang, Xin;Sun, Ran;Duan, Shixin;Lv, Dan;Jiang, Faqin;Fu, Lei. And the article was included in Bioorganic Chemistry in 2021.SDS of cas: 626-64-2 This article mentions the following:

In this study, a novel batch of thiazole-containing mitochondrial targeting agents e.g., I were designed and synthesized. Four kinds of mitochondrial targeting moieties and six kinds of linkers were designed. The screening of antiproliferative activity revealed that most compounds displayed cytotoxicity on HeLa cancer cell. In particular, II has an IC₅₀ value of 35.32μmol·L^-1 against HeLa cell. In addition, cellular respiratory activities were also tested on HeLa cancer cells. The II had a basal oxygen consumption rate of 8.84 pmol·s^-1·mL^-1. Also, II inhibited the mitochondrial respiration of HeLa cell significantly at 5μmol·L^-1, as well as a complete inhibitory of oxygen consumption for cellular ATP coupling. Furthermore, the pKa, logP, and logD under different pH conditions of all the compounds were calculated by the ACD/Percepta-PhysChem Suite, and the results manifested the correlation between physicochem. properties and chem. activity of compounds The results identify II as a promising mitochondria inhibitor and anticancer agent with appropriate physicochem. properties. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2SDS of cas: 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. SDS of cas: 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hierarchical nanostructures of a liquid crystalline block copolymer with a hydrogen-bonded calamitic mesogen was written by Pan, Hongbing;Xiao, Anqi;Zhang, Wei;Luo, Longfei;Shen, Zhihao;Fan, Xinghe. And the article was included in Polymer in 2019.HPLC of Formula: 626-64-2 This article mentions the following:

With a pyridine derivative containing a calamitic mesogen 4-((6-((4′-((4-hexylphenyl)ethynyl)-[1,1′-biphenyl]-4-yl)oxy)hexyl)oxy)pyridine (HEBC6) used as the hydrogen-bonding acceptor and polydimethylsiloxane-b-poly(2,5-bis(4-carboxy phenyl)styrene) (PDMS-b-PM3H) as the hydrogen-bonding donor, a series of supramol. liquid crystalline block copolymers (SLCBCPs) were prepared through hydrogen bonding. In the supramol. block, the calamitic mesogen was decoupled from the motion of PM3H chains by using a flexible spacer. Different microphase-separated nanostructures and liquid crystalline (LC) structures were obtained by varying the d.p. of the PM3H block and the molar ratio of HEBC6 to PDMS-b-PM3H. The SLCBCPs can self-assemble into hexagonally packed cylinders (HEX), lamellae (LAM), and inverted HEX. Smectic A phase and parallel packing of the calamitic mesogens were also observed on a smaller length scale, and these two ordered structures are synergistic and promotional. Therefore, hierarchically ordered structures can be obtained from these SLCBCPs. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2HPLC of Formula: 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. HPLC of Formula: 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Efficient Phosphorus-Free Chlorination of Hydroxy Aza-Arenes and Their Application in One-Pot Pharmaceutical Synthesis was written by Wang, Jian;Li, Yan-Hui;Pan, Song-Cheng;Li, Ming-Fang;Du, Wenting;Yin, Hong;Li, Jing-Hua. And the article was included in Organic Process Research & Development in 2020.Application In Synthesis of Pyridin-4-ol This article mentions the following:

The chlorination of hydroxy aza-arenes with bis(trichloromethyl) carbonate (BTC) and SOCl₂ has been effectively performed by refluxing with 5 weight % 4-(dimethylamino)pyridine (DMAP) as a catalyst. Various substrates are chlorinated with high yields. The obtained chlorinated aza-arenes can be used directly with simple workup for succedent one-pot synthesis on a large scale. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Application In Synthesis of Pyridin-4-ol).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Application In Synthesis of Pyridin-4-ol

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Supramolecular liquid crystals displaying competitive hydrogen bonding: Mesogenic associative chain structures using rigid and flexible pyridyl groups was written by John, Eric A.;Heltne, Michael D.;Bornowski, Evan C.;Lindberg, David J.;Carli, Joshua D.;Legare, Seth B.;Carli, John T.;Wiegel, Kurt N.. And the article was included in Molecular Crystals and Liquid Crystals in 2019.Reference of 626-64-2 This article mentions the following:

A series of liquid-crystalline supramol. copolymers formed through hydrogen bonding has been created. These polymers are composed of a bis-benzoic acid and two different pyridyl species – a small rigid bispyridyl capable of forming a mesophase when assembled and one of a pair of flexible bis pyridyl non-mesogenic “disruptor” species. The latter set of mols. consist of the pyridyl functionality separated by six or ten methylene units (6BPD and 10BPD, resp.). It was found that the associative chain polymers display monotropic characteristics depending upon the length of the methylene spacer group. The hexamethylene chain produced smectic phases up to 15% composition and cleared nematic characteristics at 70% loading. The decamethylene species eliminated smectic phases at 5% loading and displayed nematic phases up to 40% inclusion. It is believed that the increased length and flexibility of the alkyl chain allows for too much conformational mobility and freedom to efficiently form liquid-crystalline phases at high concentrations In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2Reference of 626-64-2).

Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Reference of 626-64-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem