Category: 6268-43-5

Sources of common compounds: 1,3-Di(pyridin-2-yl)urea

The chemical industry reduces the impact on the environment during synthesis 6268-43-5, I believe this compound will play a more active role in future production and life.

Reference of 6268-43-5, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.6268-43-5, name is 1,3-Di(pyridin-2-yl)urea, molecular formula is C11H10N4O, molecular weight is 214.22, as common compound, the synthetic route is as follows.

For R3 = NH-py and R1 = py in Example Scheme ES, the following example can be listed:? Using 10.0 mol% Zn(OAc)2.17H20, 1.0 equiv ACDG-NH-CO-NH-ACDG 5a, 52.0 equivisopropanol (ha), 140 C 24 h, a GO-yield of 59% of 2-aminopyridine (6a) was determinedwith TMB as an internal standard (calculated based on the formation of 2.0 equiv 2- aminopyridine (6a) = 100 % GO-yield).

The chemical industry reduces the impact on the environment during synthesis 6268-43-5, I believe this compound will play a more active role in future production and life.

Reference:
Patent; UNIVERSITEIT ANTWERPEN; MAES, Bert; WYBON, Clarence; CHEN, Chen; BHEETER, Charles Beromeo; SERGUEEV, Serguei; (88 pag.)WO2017/46133; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Sources of common compounds: 1,3-Di(pyridin-2-yl)urea

The chemical industry reduces the impact on the environment during synthesis 6268-43-5, I believe this compound will play a more active role in future production and life.

Reference of 6268-43-5, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.6268-43-5, name is 1,3-Di(pyridin-2-yl)urea, molecular formula is C11H10N4O, molecular weight is 214.22, as common compound, the synthetic route is as follows.

For R3 = NH-py and R1 = py in Example Scheme ES, the following example can be listed:? Using 10.0 mol% Zn(OAc)2.17H20, 1.0 equiv ACDG-NH-CO-NH-ACDG 5a, 52.0 equivisopropanol (ha), 140 C 24 h, a GO-yield of 59% of 2-aminopyridine (6a) was determinedwith TMB as an internal standard (calculated based on the formation of 2.0 equiv 2- aminopyridine (6a) = 100 % GO-yield).

The chemical industry reduces the impact on the environment during synthesis 6268-43-5, I believe this compound will play a more active role in future production and life.

Reference:
Patent; UNIVERSITEIT ANTWERPEN; MAES, Bert; WYBON, Clarence; CHEN, Chen; BHEETER, Charles Beromeo; SERGUEEV, Serguei; (88 pag.)WO2017/46133; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem