Category: 628-13-7

Preparation of Pyridinium-Functionalized Magnetic Adsorbent and Its Application for Nitrate Removal from Aqueous Solution was written by Ma, F.;Du, H. T.;Wang, Q.;Li, R. H.;Zhang, Z. Q.. And the article was included in Water, Air, & Soil Pollution in 2015.Synthetic Route of C5H6ClN This article mentions the following:

A novel magnetic pyridinium-functionalized mesoporous silica adsorbent (Fe₃O₄@SiO₂@Py-Cl) was synthesized for nitrate removal from aqueous solutions The adsorption performances were investigated by varying exptl. conditions such as pH, contact time, and initial concentration The adsorbent was characterized by transmission electron microscopy (TEM), XPS, Fourier transform IR (FT-IR) spectroscopy, and magnetic hysteresis loops. The results showed that the adsorption equilibrium could be reached within 30 min and the kinetic data were fitted well by pseudo-second-order and intra-particle diffusion model. The adsorbent exhibited a favorable performance, and its maximum adsorption capacity calculated by the Langmuir isotherm model was 1.755 mmol/g. The nitrate adsorption mechanism was mainly controlled by the material through ion exchange of nitrate with chloridion, as determined by XPS. This study indicated that this novel pyridinium-functionalized mesoporous material had excellent adsorption capacity. Meanwhile, compared with other adsorbents, it could remove nitrate fast and easy to be collected by magnetic separation, showing great potential application for nitrate removal from aqueous solution In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Synthetic Route of C5H6ClN).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine has a conjugated system of six 锜?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H鐪塩kel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Synthetic Route of C5H6ClN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors was written by Esposito, Anna;De Gregorio, Eliana;De Fenza, Maria;D’Alonzo, Daniele;Satawani, Anil;Guaragna, Annalisa. And the article was included in RSC Advances in 2019.Application In Synthesis of Pyridinehydrochloride This article mentions the following:

The synthesis of deflazacort (DFZ) and a preliminary evaluation of its microbial activity against the human pathogens Acinetobacter baumannii and Staphylococcus aureus is herein reported. While DFZ is inactive, one of its synthetic precursors showed a strong antibacterial activity against both Gram-neg. and -pos. bacteria. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Application In Synthesis of Pyridinehydrochloride).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Application In Synthesis of Pyridinehydrochloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis and properties of polyimides containing tetraphenylnaphthalene units was written by Morikawa, Atsushi;Karube, Chihiro;Sakaki, Yu. And the article was included in High Performance Polymers in 2016.Recommanded Product: Pyridinehydrochloride This article mentions the following:

Aromatic polyimides (PI1x) with a tetraphenylnaphthalene unit between ether linkages were synthesized from 1,4-bis[4-(aminophenoxy)phenyl]-2,3-diphenylnaphthalene (1) and various tetracarboxylic dianhydrides by a conventional two-step procedure that included ring-opening polymerization in N-methyl-2-pyrrolidone and subsequent thermal cyclic dehydration. PI1x were characterized by X-ray diffraction, differential scanning calorimetry, thermogravimetry, and dynamic mech. anal. PI1x had glass transition temperatures in the range of 270 to 315鎺?and all PI1x were amorphous. The structure-property relationships of these PIs were examined and compared with those of polyimides (PI2x) from 4,4′-bis(4-aminophenoxy)biphenyl (2) and polyimides (PI3x) from 1,4-bis(4-aminophenyl)-2,3-diphenylnaphthalene (3). Water absorption and dielec. constants (钄? of the PIs were also compared and discussed on the basis of imide content per repeating unit. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Recommanded Product: Pyridinehydrochloride).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Recommanded Product: Pyridinehydrochloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A study on the reaction pathway for isomerization of tetrahydrotricyclopentadiene using ionic liquid catalyst was written by Kim, Dae Hyun;Han, Jeong-Sik;Jeon, Jong-Ki;Yim, Jin-Heong. And the article was included in Kongop Hwahak in 2015.Safety of Pyridinehydrochloride This article mentions the following:

The kinetic behavior of tetrahydrotricyclopentadiene (THTCPD) isomerization was studied by using two kinds of chloroaluminate ionic liquid (IL) catalyst with different Lewis acidity. THTCPD isomerization pathway was discussed under the different temperature and time as reaction parameters using IL catalysts consisting of 1-butyl-3-methylimidazolun chloride (BMIC)/AlCl₃ with low acidity and pyridine hydrochloride (PHC)/AlCl₃ with high acidity. The conversion of THTCPD isomerization increased with increasing Lewis acidity of IL catalyst. The THTCPD isomerization pathway changed as a function of reaction temperature and catalyst acidity. In the case of BMIC/AlCl₃ IL catalyst, THTCPD isomerization pathway was similar to that of using conventional AlCl₃ catalyst. However, two different types of addnl. pathways (endo, exo, endo-NB 閳?exo, exo, endo-NB 閳?exo, exo, exo-NB and endo, exo, endo-NB 閳?exo, exo, endo-NB 閳?exo, exo, exo- CP) were appeared when using PHC/AlCl₃ IL catalyst. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Safety of Pyridinehydrochloride).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Safety of Pyridinehydrochloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Design, Synthesis and Anticancer Activity of Aza Heterocycles Containing Gallate Moiety (Part III) was written by El-Ebiary, N. M.;Swellem, R. H.;Nawwar, G. A. M.. And the article was included in Pharmaceutical Chemistry Journal in 2017.Related Products of 628-13-7 This article mentions the following:

Our previously reported compound, 3-(2-hydroxy-3,4-dimethoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde, was allowed to react with acetophenone, Et cyanoacetate and/or malononitrile to give the corresponding compounds, e.g. I, which were treated with thiourea afforded thiopyrimidine derivatives The coupling of 3a and 3b with 2′,3′,4′,6′-tetra-O-acetyl-_-D-glucopyranosyl bromide (4) afforded compounds 5a and 5b, resp. Reaction of I with acetophenone yielded pyridone derivative II, which was fused in pyridine hydrochloride to give demethylated product. The coupling of II with some cyclic and acyclic halosugars afforded various N-glycoside derivatives New compounds were tested for their antitumor activity on MCF-7 human breast adenocarcinoma cell line and HepG2 liver carcinoma cell line. Almost all tested compounds exhibited antitumor activity, especially II, which displayed the most potent inhibitory activity with IC₅₀ = 2.97 and 2.67 g/mL against MCF-7 and HepG2 cell lines, resp. Compound 6 was tested for its acute toxicity (LD) and found to have very low toxicity based on LD₅₀ values (no label > 600 < 2000 mg/kg) as recommended by the Organization for Economic Co-operation and Development. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Related Products of 628-13-7).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Related Products of 628-13-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples was written by Wang, Dan-Dan;Jin, Qiang;Zou, Li-Wei;Hou, Jie;Lv, Xia;Lei, Wei;Cheng, Hai-Ling;Ge, Guang-Bo;Yang, Ling. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2016.Related Products of 628-13-7 This article mentions the following:

A highly selective and sensitive bioluminescent sensor compound (DME) for human carboxylesterase 1 (hCE1) was designed and synthesized by introduction of a MeOH moiety into D-luciferin and well characterized. DME could be used for real-time monitoring of hCE1 activities in complex biol. samples and for bio-imaging of endogenous hCE1 in living SKOV-3-Luc⁺ cells. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Related Products of 628-13-7).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Related Products of 628-13-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Regioselective synthesis and biological evaluation of N-substituted 2-aminoquinazolin-4-ones was written by Liao, Zhen-Yuan;Yeh, Wen-Hsiung;Liao, Pen-Yuan;Liu, Yu-Ting;Chen, Ying-Cheng;Chen, Yi-Hung;Hsieh, Tsung-Han;Lin, Chia-Chi;Lu, Ming-Hsuan;Chen, Yi-Song;Hsu, Ming-Chih;Li, Tsai-Kun;Chien, Tun-Cheng. And the article was included in Organic & Biomolecular Chemistry in 2018.Related Products of 628-13-7 This article mentions the following:

The reaction of Me anthranilates 2-NH₂-R¹-C₆H₃C(O)OCH₃ (R¹ = 5-Cl, 4,5-(OCH₃)₂, 5-OCH₃, 5-Br) with N-arylcyanamides R²NHCN (R² = C₆H₅, 4-H₃CC₆H₄, (CH₂)₂CH₃, etc.) in the presence of p-TsOH in t-BuOH under reflux afforded predominantly 3-arylquinazolin-4-ones I (R³ = H, 6-Cl, 6,7-(OCH₃)₂, 6-OCH₃, 6-Br). In contrast, the reaction of the same reactants with TMSCl in t-BuOH at 60 °C followed by the Dimroth rearrangement in aqueous ethanolic sodium hydroxide gave exclusively the regioisomers, 2-(N-arylamino)quinazolin-4-ones II. The regioselective synthesis of N-aryl-substituted 2-aminoquinazolin-4-ones I (R² = 2-bromophenyl, 2-bromo-4-methylphenyl, 2-bromo-4-fluorophenyl), II can be further applied to the synthesis of benzimidazo[2,1-b]quinazolin-12-ones III (R⁴ = H, CH₃, F) and IV. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Related Products of 628-13-7).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Related Products of 628-13-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Core Level Shifts of Hydrogenated Pyridinic and Pyrrolic Nitrogen in the Nitrogen-Containing Graphene-Based Electrocatalysts: In-Plane vs. Edge Defects was written by Matanovic, Ivana;Artyushkova, Kateryna;Strand, Matthew B.;Dzara, Michael J.;Pylypenko, Svitlana;Atanassov, Plamen. And the article was included in Journal of Physical Chemistry C in 2016.Computed Properties of C5H6ClN This article mentions the following:

A combination of N 1s XPS and 1st principles calculations of N-containing model electrocatalysts was used to elucidate the nature of the N defects that contribute to the binding energy (BE) range of the N 1s XPS spectra of these materials ≳400 eV. Exptl. core level shifts were obtained for a set of model materials, N-doped C nanospheres, Fe-N-C nanospheres, polypyrrole, polypyridine, and pyridinium chloride, and were compared to the shifts calculated using d. functional theory. The broad peak positioned at ∼400.7 eV in the N 1s XPS spectra of N-containing catalysts, which is typically assigned to pyrrolic N, contains contributions from other hydrogenated N species such as hydrogenated pyridinic functionalities. Namely, N 1s BEs of hydrogenated pyridinic-N and pyrrolic-N were calculated as 400.6 and 400.7 eV, resp., using the Perdew-Burke-Ernzerhof exchange-correlation functional. A special emphasis was placed on the study of the differences in the XPS imprint of N-containing defects that are situated in the plane and on the edges of the graphene sheet. D. functional theory calculations for BEs of the N 1s of in-plane and edge defects show that hydrogenated N defects are more sensitive to the change in the chem. environment in the C matrix than the nonhydrogenated N defects. Calculations also show that edge-hydrogenated pyridinic-N and pyrrolic-N defects only contribute to the N 1s XPS peak located at ∼400.7 eV if the graphene edges are oxygenated or terminated with bare C atoms. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Computed Properties of C5H6ClN).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Computed Properties of C5H6ClN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Express photolithographic DNA microarray synthesis with optimized chemistry and high-efficiency photolabile groups was written by Sack, Matej;Hoelz, Kathrin;Holik, Ann-Katrin;Kretschy, Nicole;Somoza, Veronika;Stengele, Klaus-Peter;Somoza, Mark M.. And the article was included in Journal of Nanobiotechnology in 2016.Reference of 628-13-7 This article mentions the following:

Background: DNA microarrays are a core element of modern genomics research and medical diagnostics, allowing the simple and simultaneous determination of the relative abundances of hundreds of thousands to millions of genomic DNA or RNA sequences in a sample. Photolithog. in situ synthesis, using light projection from a digitally-controlled array of micromirrors, has been successful at both com. and laboratory scales. The advantages of this synthesis method are its ability to reliably produce high-quality custom microarrays with a very high spatial d. of DNA features using a compact device with few moving parts. The phosphoramidite chem. used in photolithog. synthesis is similar to that used in conventional solid-phase synthesis of oligonucleotides, but some unique differences require an independent optimization of the synthesis chem. to achieve fast and low-cost synthesis without compromising microarray quality. Results: High microarray quality could be maintained while reducing coupling time to a few seconds using DCI activator. Five coupling activators were compared, which resulted in microarray hybridization signals following the order ETT > Activator 42 > DCI [Much Greather Than] BTT [Much Greather Than] pyridinium chloride, but only the use of DCI led to both high signal and highly uniform feature intensities. The photodeprotection time was also reduced to a few seconds by replacing the NPPOC photolabile group with the new thiophenyl-NPPOC group. Other chem. parameters, such as oxidation and washing steps were also optimized. Conclusions: Highly optimized and microarray-specific phosphoramidite chem., along with the use of the very photosensitive thiophenyl-NPPOC protecting group allow for the synthesis of high-complexity DNA arrays using coupling times of 15 s and deprotection times of 9 s. The resulting overall cycle time (coupling to coupling) of about 50 s, results in a three-fold reduction in synthesis time. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Reference of 628-13-7).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Reference of 628-13-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Anion-Controlled Cation-Exchange Process: Intercalating α-Titanium Phosphate through Direct Ion Exchange with Alkylammonium Salts was written by Wang, Chunyang;Cheng, Qingyan;Wang, Yanji. And the article was included in Inorganic Chemistry in 2018.Formula: C5H6ClN This article mentions the following:

Several alkylammonium salts were used in the study of α-titanium phosphate (α-TiP) intercalation chem. The characterization results demonstrated that the expected intercalation by direct ion exchange could be successfully achieved without any addition of an extra amine substance. The authors’ findings are different from the current opinion that by the ion-exchange method, without the assistance of bases, large cations are difficult to exchange into the narrow interlayer space of α-tetravalent metal phosphate directly because of the small interlayer distance. Studies found that alkylammonium cations, for example, n-butylammonium cation, could be directly exchanged into the interlayer space merely by choosing salts with appropriate anions such as phosphate, phosphite, sulfite, citrate, and malate ions. In the case of phosphates, besides n-butylammonium, the exchange of n-hexylammonium, cyclohexylammonium, and pyridinium with interlayer protons was studied and successfully accomplished as well. The uptake values for these four cations were 0.420, 0.595, 0.571, and 0.335 g/g, resp. A mechanism study revealed that although the relevant exchange reaction seemed only to involve the proton of α-TiP and the alkylammonium cation of the salt, the strength of the conjugate acid of the anion from the salt-the counterion-was proven to be the key factor in this process. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Formula: C5H6ClN).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Formula: C5H6ClN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem