Category: 6295-87-0

Adding a certain compound to certain chemical reactions, such as: 6295-87-0, 1-Aminopyridinium Iodide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, COA of Formula: C5H7IN2, blongs to pyridine-derivatives compound. COA of Formula: C5H7IN2

General procedure: A clean, washed boiling tube equipped with a magnetic stir bar was charged with 1-aminopyridinium iodide (1a) (0.0665 g, 0.3 mmol),(E)-chalcone (2a) (0.0520 g, 0.25 mmol) and NMP (1 mL). The mixture was stirred for 24 h at r.t. under O2 (balloon). After completion of the reaction, the mixture was poured into hypo solution (10 mL). The mixture was extracted with EtOAc (3 × 10 mL), dried over anhydrous Na2SO4 and the solvent removed under reduced pressure. The residue was purified through column chromatography using silica gel (20%EtOAc/hexane) to afford 3a.

The synthetic route of 6295-87-0 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Ravi, Chitrakar; Samanta, Supravat; Mohan, Darapaneni Chandra; Reddy, N. Naresh Kumar; Adimurthy, Subbarayappa; Synthesis; vol. 49; 11; (2017); p. 2513 – 2522;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reference of 6295-87-0 ,Some common heterocyclic compound, 6295-87-0, molecular formula is C5H7IN2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General procedure: A clean, washed boiling tube equipped with a magnetic stir bar was charged with 1-aminopyridinium iodide (1a) (0.0665 g, 0.3 mmol),(E)-chalcone (2a) (0.0520 g, 0.25 mmol) and NMP (1 mL). The mixture was stirred for 24 h at r.t. under O2 (balloon). After completion of the reaction, the mixture was poured into hypo solution (10 mL). The mixture was extracted with EtOAc (3 × 10 mL), dried over anhydrous Na2SO4 and the solvent removed under reduced pressure. The residue was purified through column chromatography using silica gel (20%EtOAc/hexane) to afford 3a.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,6295-87-0, its application will become more common.

Reference:
Article; Ravi, Chitrakar; Samanta, Supravat; Mohan, Darapaneni Chandra; Reddy, N. Naresh Kumar; Adimurthy, Subbarayappa; Synthesis; vol. 49; 11; (2017); p. 2513 – 2522;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6295-87-0, name is 1-Aminopyridinium Iodide. This compound has unique chemical properties. The synthetic route is as follows. Formula: C5H7IN2

General procedure: Potassium carbonate (9.0 mmol) for 3a-t or triethylamine (9.0 mmol) for 3u was added to a solution of 1-aminopyridinium iodide 1 (3.0 mmol) in acetonitrile (25 mL) for 3a-t or EtOH (25 mL) for 3u. The reaction mixtures were stirred vigorously for 10-20 min at room temperature to give a dark purple solution, to which electrophiles 2a-u (3.0 mmol) were added in one portion. The mixtures were stirred at rt for 3-24 h except for 3e, which was heated under reflux for 5h. Mixtures 3a-t were filtered to remove inorganic salts, which were washed with acetonitrile 3-5 times. The combined filtrates were concentrated in vacuo and the residues were purified either by gradient elution chromatography over silica gel and/or by recrystallization.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 6295-87-0, 1-Aminopyridinium Iodide.

Reference:
Article; Zhang, Hong; Wang, Zuoquan; Jabeen, Farukh; Gopinathan-Pillai, Girinath; Zhou, Wenfeng; Steel, Peter J.; Hall, C. Dennis; Katritzky, Alan R.; Tetrahedron Letters; vol. 57; 1; (2016); p. 20 – 24;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 6295-87-0, Adding some certain compound to certain chemical reactions, such as: 6295-87-0, name is 1-Aminopyridinium Iodide,molecular formula is C5H7IN2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6295-87-0.

To a dry CH3CN (40 mL) solution of 1-aminopyridinium iodide (1.12 g, 5.02 mmol) was added 4-dimethylaminopyridine (DMAP) (59.9 mg, 0.490 mmol), potassium carbonate (2.08 g, 15.0 mmol), and benzoylchloride (724.4 mg, 5.15 mmol). Then, the reaction mixture was stirred for 7 h at rt. The suspension was concentrated in vacuo. The product was extracted with CH2Cl2 and filtered to remove inorganic impurities. After volatiles were removed under reduced pressure, the crude product was purified by flash column chromatography on Fuji Silysia silica gel FL100D (CH2Cl2/MeOH=20/1) to afford N-benzoyliminopyridinium ylide (2c) as a white solid (668 mg, 3.37 mmol, 67% yield). The spectral data was identical with the reported literatures. 11 1H NMR (400 MHz, CDCl3) delta 8.85 (m, 2H; NC5H2HH2), 8.16 (m, 2H; C6H2H3), 7.92 (m, 1H; NC5H2HH2), 7.68 (m, 2H; NC5H2HH2), 7.42 (m, 3H; C6H2H3).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 6295-87-0, 1-Aminopyridinium Iodide, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Miyazawa, Kazuki; Koike, Takashi; Akita, Munetaka; Tetrahedron; vol. 72; 48; (2016); p. 7813 – 7820;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Related Products of 6295-87-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 6295-87-0, name is 1-Aminopyridinium Iodide. This compound has unique chemical properties. The synthetic route is as follows.

But-3-yn-2-one (0.71g, 10.4mmol) and 1-aminopyridinium iodide (2.69g, 12mmol) were dissolved in DMSO (21mL) and treated with K2CO3 (1.30g, 9.36mmol) and KOH (1.17g, 20.8mmol). The mixture was stirred for 6hat room temperature. Then the reaction mixture was poured in water (50mL) and extracted with ethyl acetate (15mL¡Á3), the combined organic phase was washed with brine (20mL¡Á2), dried over anhydrous Na2SO4 and concentrated. The residue was purified by column chromatography (eluent: petroleum ether/ethyl acetate=4:1) to provide 12o as a pale yellow solid (0.53g, 31%). Mp: 94-96C (Lit.Mp [19]: 102-103C). 1H NMR (400MHz, CDCl3): delta=2.56 (s, 3H), 7.01 (t, J=8.0Hz, 1H), 7.47 (t, J=8.0Hz, 1H), 8.34-8.40 (m, 2H), 8.54 (d, J=8.0Hz, 1H).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 6295-87-0, 1-Aminopyridinium Iodide.

Reference:
Article; Li, Ri-Dong; Wang, Hui-Ling; Li, Ying-Bo; Wang, Zhong-Qing; Wang, Xin; Wang, Yi-Tao; Ge, Ze-Mei; Li, Run-Tao; European Journal of Medicinal Chemistry; vol. 93; (2015); p. 381 – 391;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem