Category: 636-73-7

Renaud, Justin B. published the artcileNormalization of LC-MS mycotoxin determination using the N-alkylpyridinium-3-sulfonates (NAPS) retention index system, Category: pyridine-derivatives, the publication is Journal of Chromatography A (2021), 461901, database is CAplus and MEDLINE.

A major challenge for LC-MS anal. is the ability to compare data between laboratories and across instrument platforms. Currently, mycotoxin determination relies on dereplication strategies based on physicochem. properties such as the m/z of the precursor and product ions. Unlike these intrinsic properties, retention time (tR) is an extrinsic property impacted by LC conditions, including mobile phases and column chem., making exchange of data between groups difficult. To address this, we are introducing the concept of incorporating an electrospray compatible, retention index (RI) system based on a series of N-alkylpyridinium-3-sulfonates (NAPS) into routine mycotoxin determination These standards of differing alkyl chain length span RI units from 100 to 2000, are UV active and have fixed pos. and neg. charges for electrospray ionization in either mode. Using high resolution LC-MS/MS, the RIs of 96 mycotoxins and fungal secondary metabolites were normalized as a proof of concept with the NAPS RI system under multiple pH, column and gradient chromatog. conditions. This method was then applied to the anal. of a crude extract of Penicillium roqueforti, where we were able to decrease the number of false positives by implementing an RI filter as well as a secondary correction factor. Addnl., we developed software that allows users to convert published RIs to a predicted tR values. Integration of the NAPS RI system into routine LC-MS anal. will improve compound identifications and help facilitate ease of data sharing.

Journal of Chromatography A published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Liu, Shan-Shan published the artcileSulfonic Groups Lined along Channels of Metal-Organic Frameworks (MOFs) for Super-Proton Conductor, Computed Properties of 636-73-7, the publication is Inorganic Chemistry (2020), 59(1), 396-402, database is CAplus and MEDLINE.

Designing high-performance proton-conducting metal-organic frameworks simultaneously having highly hydrothermal stability and a high-d. proton carrier remains a great challenge. Fe-MIL-88B is a classic metal-organic framework (MOF) with a large-size one-dimensional (1D) channel lined with a high-d. uncoordinated metal atom for postfunctionalization; however this MOF cannot act as a proton conductor due to the weak hydrothermal stability. Here, we prepared an ultrastable isostructure Cr-MIL-88B, which is subsequently functionalized by anchoring 3-pyridinesulfonic acid and 2-(4-pyridyl) ethanesulfonic acid on the naked Cr atoms exposed on the surface of the host-framework, producing two new MOFs, i.e. Cr-MIL-88B-pyridine sulfonic acid (abbreviated as Cr-MIL-88B-PSA) and Cr-MIL-88B-pyridine ethanesulfonic acid (abbreviated as Cr-MIL-88B-PESA). Thus, Cr atoms on the host framework were modified by functional sulfonic groups, which stick out toward the center of the channel forming ordered high-d. sulfonic groups as proton donors along the open channel and achieving the highest proton conductivity of 4.50 × 10^-2 S cm^-1 for Cr-MIL-88B-PESA and 1.58 × 10^-1 S cm^-1 for Cr-MIL-88B-PSA, surpassing that of the Nafion membrane.

Inorganic Chemistry published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Computed Properties of 636-73-7.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Korthals, Brigitte published the artcileNickel(II)-Methyl Complexes with Water-Soluble Ligands L [(salicylaldiminato-κ²N,O)NiMe(L)] and Their Catalytic Properties in Disperse Aqueous Systems, Application of Pyridine-3-sulfonic acid, the publication is Organometallics (2007), 26(6), 1311-1316, database is CAplus.

Neutral (salicylaldiminato)nickel(II) Me complexes [{6-C(H):NAr-2,4-I₂C₆H₂O-κ²N,O}NiMe(L)] (Ar = 2,6-{3,5-(F₃C)₂C₆H₃}₂C₆H₃) with different water-soluble ligands L (2a, L = 1,3,5-triaza-7-phosphaadamantane; 2b, L = hexamethylenetetramine (urotropine); 2c, L = tetraethylammonium pyridine-3-sulfonate; 2d, L = amino-terminated poly(ethylene glycol) monomethoxy ether) were prepared 2A–d are potentially water-soluble catalyst precursors for ethylene polymerization, which form a water-insoluble active site [{κ²-N,O}NiR(ethylene)] (R = growing chain). Only complex 2d was water-soluble (>2 mmol L^-1); 2c is soluble in water/2-propanol mixtures In toluene as a reaction medium, only the relatively weakly coordinated tertiary amine complex 2b is polymerization active (1.7 × 10⁴ TO). In aqueous systems 2c,d are also active due to compartmentalization of the active site in the polymer particles and of L in the aqueous phase. Polyethylene particle sizes vary from 18 nm (dispersions formed with 2d) to over 0.5 μm (2c) to suspensions (2b) depending on the initial state of the reaction mixture, correlated with catalyst solubility

Organometallics published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Application of Pyridine-3-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lopez-Fontal, Elkin published the artcileShip in a bottle: confinement-promoted self-assembly, HPLC of Formula: 636-73-7, the publication is Chemical Science (2018), 9(7), 1760-1768, database is CAplus and MEDLINE.

Understanding self-assembly in confined spaces is essential to fully understand mol. processes in confined cell compartments and will offer clues on the behavior of simple confined systems, such as protocells and lipid-vesicle based devices. Using a model system composed of lipid vesicles, a membrane impermeable receptor and a membrane-permeable ligand, we have studied in detail how compartmentalization modulates the interaction between the confined receptor and its ligand. We demonstrate that confinement of one of the building blocks stabilizes complex self-assembled structures to the extent that dilution leads, counterintuitively, to the formation of long range assemblies. The behavior of the system can be explained by considering a confinement factor that is analogus, although not identical, to the effective molarity for intramol. binding events. The confinement effect renders complex self-assembled species robust and persistent under conditions where they do not form in bulk solution Moreover, we show that the formation of stable complex assemblies in systems compartmentalized by semi-permeable membranes does not require the prior confinement of all components, but only that of key membrane impermeable building blocks. To use a macroscopic analogy, lipid vesicles are like ship-in-a bottle constructs that are capable of directing the assembly of the confined ship following the confinement of a few key wooden planks. Therefore, we believe that the confinement effect described here would have played an important role in shaping the increase of chem. complexity within protocells during the first stages of abiogenesis. Addnl., we argue that this effect can be exploited to design increasingly efficient functional devices based on comparatively simple vesicles for applications in biosensing, nanoreactors and drug delivery vehicles.

Chemical Science published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, HPLC of Formula: 636-73-7.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Sgaragli, Gianpietro published the artcileRole of taurine in thermoregulation and motor control: behavioral and cellular studies, Recommanded Product: Pyridine-3-sulfonic acid, the publication is Advances in Experimental Medicine and Biology (1996), 527-535, database is CAplus.

Taurine may have a role in the striatonigral system of the rat. Considering that, whether a neurotransmitter or a neuromodulator, taurine must be recognized before initiating its action, in the present contribution a structure-activity relationship study is presented which gives some information on the nature of a possible recognition site in the rabbit brain, helping to explain the role of endogenous taurine in the central mechanisms of thermoregulation.

Advances in Experimental Medicine and Biology published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C15H21BO3, Recommanded Product: Pyridine-3-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Bornholdt, Jan published the artcileRing Opening of Pymisyl-Protected Aziridines with Organocuprates, Application In Synthesis of 636-73-7, the publication is Chemistry – A European Journal (2010), 16(41), 12474-12480, S12474/1-S12474/100, database is CAplus and MEDLINE.

The pyrimidine-2-sulfonyl (pymisyl) group is introduced as a new protecting group that can be used to activate aziridines towards ring opening. It is readily introduced and removed under mild conditions. Regioselective ring opening of pymisyl-protected 2-methylaziridine with organocuprates gives the corresponding sulfonamides in high yields, and the pymisyl group can subsequently be removed upon treatment with a thiolate. The versatility of this new nitrogen protecting group is illustrated with a new synthesis of Selegiline, a monoamine oxidase-B inhibitor marketed for the treatment of Parkinson’s disease.

Chemistry – A European Journal published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Application In Synthesis of 636-73-7.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Carballo, Rosa published the artcileSupramolecular networks through second-sphere coordination based on 1D metal-4,4′-dipyridyldisulfide coordination polymers and hydrogenfumarate or sulfonate anions, Computed Properties of 636-73-7, the publication is Polyhedron (2012), 31(1), 118-127, database is CAplus.

Four H-bonded assemblies [M(dpds)₂(OH₂)₂]A₂·nH₂O (A = anion) are described. These assemblies result from the 2nd-sphere coordination interactions between the 1-dimensional coordination polymers [M(dpds)₂(OH₂)₂]²⁺, M = Zn(II), and Cu(II), dpds = 4,4′-dipyridyldisulfide, and the pyridine-3-sulfonate (3pySO₃^–) or hydrogenfumarate (Hfum^–) anions. Significantly, supramol. structural variations are observed depending on the presence of H₂O lattice mols., which formed discrete aggregates when the Hfum^– anion was used. The effects of geometrical variations in the building blocks are also evident on using Jahn-Teller-distorted divalent Cu(II) ions or regular octahedral species based on Zn(II) ions. The 2nd-sphere effects on the stabilization of the compounds are illustrated by TGA experiments

Polyhedron published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Computed Properties of 636-73-7.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Solov’ev, M. Yu. published the artcileSynthesis, structure, and properties of a number of 3-sulfanilamidic derivatives of pyridine, Application of Pyridine-3-sulfonic acid, the publication is Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya (2004), 47(2), 28-36, database is CAplus.

3-Pyridinesulfochloride was synthesized by the dehydroxochloration of 3-pyridinesulfonic acid and used for the synthesis of a number of primary and secondary sulfonylamides and also (3-pyridinesulfonyl)-pyperidinecarboxylic acids and their amides NMR ¹H-spectra of the synthesized compounds are described and interpreted. The rating of their potential suitability for biol. tests is carried out according to Lipinski rules and “lead-like”-conception. Also, the rating of ability of the received compounds to penetrate through the hemato-encephalic barrier was made using the special neuron-net model. The conclusion about the expediency of testing of the synthesized compounds is made for the area of development of CNS acting drugs.

Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C6H16OSi, Application of Pyridine-3-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Alo, Babajide I. published the artcileDirected metalation of pyridinesulfonamides. Synthesis of pyridine-fused isothiazoles and 1,2-oxathioles, Application of Pyridine-3-sulfonic acid, the publication is Journal of Heterocyclic Chemistry (1992), 29(1), 61-4, database is CAplus.

4-Lithio-N–tert-butylpyridine-3-sulfonamide reacted with Ph₂CO or CO₂ to give the corresponding intermediates, which on appropriate treatment gave the addition product I (from Ph₂CO reaction product) or isothiazolo[5,4-c]pyridin-3-one 1,1-dioxides II (R = H, Me₃C) (from CO₂ reaction product). Metalation of 2- and 4-[N,N-(dialkylamino)sulfonyl]pyridines with LiN(CHMe₂)₂ gave anions which reacted with Ph₂CO to give carbinols, which cyclized thermally to 1,2-oxathiolo[3,4-b]- III and -[4,3-c]pyridine dioxide IV, resp.

Journal of Heterocyclic Chemistry published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Application of Pyridine-3-sulfonic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Xing, Kai published the artcileA self-calibrating dual responsive platform for the sensitive detection of sulfite and sulfonic derivatives based on a robust Hf(IV) metal-organic framework, Computed Properties of 636-73-7, the publication is Chemical Communications (Cambridge, United Kingdom) (2020), 56(4), 631-634, database is CAplus and MEDLINE.

A robust hafnium-based metal organic framework, Hf-PBTA, with sensitive and self-calibrating dual-emissive fluorescence response towards sulfite and sulfonic derivatives, including antibiotic sulfamethazine, has been developed, which shows fast detection of sulfite ions at a concentration as low as 76 ppb. The opposite response tendency from two radiative pathways towards aromatic sulfonic mols. and sulfite anions stems from the synergistic effect of the pyridine protonation effect, π-π stacking interaction and intramol. twist motion.

Chemical Communications (Cambridge, United Kingdom) published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C15H14O3, Computed Properties of 636-73-7.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem