Application of 65370-42-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 65370-42-5, name is 4-Chloro-2-nitropyridine. This compound has unique chemical properties. The synthetic route is as follows.
Compound 8 (4g, 0.03mol) was added to a 100mL eggplant-shaped bottle, NMP 30mL was added, stirred, and added sequentially Diisopropylethylamine (10 g, 0.08 mol), compound 9 (4.8 g, 0.03 mol), then reacted at 150 C for 24 h, using thin layer chromatography(TLC) followed the reaction. After 24 h, TLC showed the end of the reaction. Part of the solvent was evaporated under reduced pressure. After suction filtration, drying and recrystallization, 3.20 g of a gray solid compound 10 was obtained in a yield of 50%.
According to the analysis of related databases, 65370-42-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Shanghai University of Engineering Science; Yin Lingfeng; Mao Yongjun; Zhao Zhiwei; Bu Lehao; Wu Pengfei; Wang Han; (12 pag.)CN109942576; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem