Category: 65719-09-7

Related Products of 65719-09-7, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.65719-09-7, name is Methyl 2-methylnicotinate, molecular formula is C8H9NO2, molecular weight is 151.16, as common compound, the synthetic route is as follows.

Step A. 2-Chloromethyl-pyridine-3-carboxylic acid methyl ester A solution of methyl 2-methylnicotinate (20.0 g, 0.132 mol) and trichloroisocyanuric acid (46.0 g, 0.198 mol) in dichloromethane (100 mL) was stirred at room temperature overnight. The reaction mixture was then washed with saturated aqueous sodium carbonate and saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate, filtered, and the solvent evaporated in vacuo to provide the title compound as a yellow liquid (11.2 g), which was used as such in the next step.

The chemical industry reduces the impact on the environment during synthesis 65719-09-7, I believe this compound will play a more active role in future production and life.

Reference:
Patent; Wyeth; US2002/198191; (2002); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 65719-09-7, Methyl 2-methylnicotinate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C8H9NO2, blongs to pyridine-derivatives compound. Computed Properties of C8H9NO2

a) 2-methylnicotinic Acid Following the procedure of Example 1(g), except substituting methyl-2-methylnicotinate for N-(4-pyridinylmethoxycarbonyl)-L-leucine methyl ester, the title compound was prepared as a white solid (1.6 g, 100percent). MS (ESI): 138.2 (M+H)+.

The synthetic route of 65719-09-7 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Halbert, Stacie Marie; Michaud, Evelyne; Thompson, Scott Kevin; Veber, Daniel Frank; US2002/49316; (2002); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem