Category: 69142-64-9

The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 69142-64-9, name is Ethyl 6-aminopicolinate. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C8H10N2O2

To a solution of ethyl 6-aminopicolinate (91; 5.5 g, 33 mmol) in t-BuOH (120 mL) and acetone (40 mL) was added DMAP (0.08g, 0.66 mmol) and di-t-butyl dicarbonate (10.8 g, 49.5 mmol). The reaction mixture was stirred at room temperature for 18 h. The solvent was removed by concentration under reduced pressure and a mixture of hexane/dichloromethane (180 mL, 3:1) was added. The resulting mixture was cooled to – 20 0C for 2 h. The resulting solids were collected by filtration and dried to afford ethyl 6- (tert-butoxycarbonylamino)picolinate 92 (11.0 g, 91%).

With the rapid development of chemical substances, we look forward to future research findings about 69142-64-9.

Reference:
Patent; SIRTRIS PHARMACEUTICALS, INC.; VU, Chi, B.; DISCH, Jeremy, S.; NG, Pui, Yee; BLUM, Charles, A.; PERNI, Robert, B.; WO2010/3048; (2010); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reference of 69142-64-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 69142-64-9, name is Ethyl 6-aminopicolinate. This compound has unique chemical properties. The synthetic route is as follows.

Step 2. Preparation of ethyl 6-(tert-butoxycarbonylamino)picolinate (79):To a solution of ethyl 6-aminopicolinate 78 (5.5 g, 33 mmol) in £-BuOH (120 mL) and acetone (40 mL) was added 4-dimethylaminopyridine (0.08g, 0.66 mmol) and di-tert-butyl dicarbonate (10.8 g, 49.5 mmol). The reaction mixture was stirred at room temperature for 18 h. The solvent was removed by concentration under reduced pressure and a mixture of hexane/dichloromethane (180 mL, 3:1) was added. The resulting mixture was cooled to -20 0C for 2 h. The resulting solids were collected by filtration and dried to afford 79 (11.O g, 91 % yield).

According to the analysis of related databases, 69142-64-9, the application of this compound in the production field has become more and more popular.

Reference:
Patent; SIRTRIS PHARMACEUTICALS, INC.; OALMANN, Christopher; PERNI, Robert, B.; VU, Chi, B.; WO2010/37127; (2010); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem