Category: 700-16-3

Ionic hydrogenation of naphthyl tetrafluoropyridin-4-yl ethers as a new route to 5,6,7,8-tetrahydronaphthols was written by Zhu, Zhongwei;Koltunov, Konstantin Yu.. And the article was included in Mendeleev Communications in 2020.Computed Properties of C5F5N The following contents are mentioned in the article:

O-Tetrafluoropyridin-4-yl-protected naphthols underwent regioselective reduction with cyclohexane in the presence of aluminum chloride to afford the corresponding 5,6,7,8-tetrahydronaphthyl ethers. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Computed Properties of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Computed Properties of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Gallium Hydrides and O/N-Donors as Tunable Systems in C-F Bond Activation was written by Jaeger, Alma D.;Walter, Ruben;Ehm, Christian;Lentz, Dieter. And the article was included in Chemistry – An Asian Journal in 2018.Electric Literature of C5F5N The following contents are mentioned in the article:

The gallium hydrides (iBu)₂GaH , LiGaH₄ and Me₃N·GaH₃ (1 c) hydrodefluorinate vinylic and aromatic C-F bonds when O and N donor mols. are present. LiGaH₄ exhibits the highest reactivity. Quant. conversion to the hydrodefluorination (HDF) products could be observed for hexafluoropropene and 1,1,3,3,3-pentafluoropropene, 94% conversion of pentafluoropyridine and 49% of octafluorotoluene. Whereas for the HDF with LiGaH₄ high conversions are observed when catalytic amounts of O donor mols. were added, for (iBu)₂GaH, the addition of N donor mols. lead to higher conversions. The E/Z selectivity of the HDF of 1,1,3,3,3-pentafluoropropene is donor-dependent. DFT studies show that HDF proceeds in this case via the gallium hydride dimer-donor species and a hydrometalation/elimination sequence. Selectivities are sensitive to the choice of donor, as the right donor can lead to an on/off switching during catalysis, i.e., the hydrometalation step is accelerated by the presence of a donor, but the donor dissociates prior to elimination, allowing the inherently more selective donorless gallium systems to determine the selectivity. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Electric Literature of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Electric Literature of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Robust perfluorinated porous organic networks: Succinct synthetic strategy and application in chlorofluorocarbons adsorption was written by Luo, Yali;Yang, Zhenzhen;Suo, Xian;Chen, Hao;Wang, Tao;Wang, Ziqian;Liu, Yunfei;Lyu, Yinong;Popovs, Ilja;Dai, Sheng. And the article was included in Nano Research in 2021.Computed Properties of C5F5N The following contents are mentioned in the article:

Fluorinated porous organic networks (F-PONs) have demonstrated unique properties and applications, but approaches capable of affording F-PONs with high fluorine content and robust nanoporous architecture under metal-free and easy handling conditions are still rarely reported. Herein, using polydivinylbenzene (PDVB) as an easily available precursor, a novel and straightforward approach was developed to afford F-PONs via a dehydrative Friedel-Crafts reaction using perfluorinated benzylic alcs. as the crosslinking agent promoted by Bransted acid (trifluoromethanesulfonic acid). The afforded material (F-PDVB) featured high fluorine content (22 at.%), large surface area (771 m²·g^-1), and good chem./thermal stability, rendering them as promising candidates for the adsorption of CO₂, hydrocarbons, fluorocarbons, and chlorofluorocarbons, with weight capacities up to 520 weight% being achieved. This simple methodol. can be extended to fabricate fluorinated hyper-crosslinked polymers (F-HCPs) from rigid aromatic monomers. The progress made in this work will open new opportunities to further expand the involvement of fluorinated materials in large scale applications. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Computed Properties of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Computed Properties of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Photoredox catalyzed dealkylative aromatic halogen substitution with tertiary amines was written by Lipilin, Dmitry L.;Frumkin, Alexander E.;Tyurin, Alexey Y.;Levin, Vitalij V.;Dilman, Alexander D.. And the article was included in Molecules in 2021.Application In Synthesis of 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:

A reaction of aromatic halides bearing electron-withdrawing groups with tertiary amines in the presence of an iridium catalyst under blue light irradiation is described. Products of the aromatic substitution of the halide by the dialkylamino fragment are obtained. The interaction of aryl radicals with tertiary amines to generate zwitterionic radical species is believed to be the key factor responsible for the reaction efficiency. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Application In Synthesis of 2,3,4,5,6-Perfluoropyridine).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Application In Synthesis of 2,3,4,5,6-Perfluoropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

O-Perfluoropyridin-4-yl Oximes: Iminyl Radical Precursors for Photo- or Thermal-Induced N-O Cleavage in C(sp²)-C(sp³) Bond Formation was written by Xia, Peng-Ju;Hu, Yuan-Zhuo;Ye, Zhi-Peng;Li, Xu-Jie;Xiang, Hao-Yue;Yang, Hua. And the article was included in Journal of Organic Chemistry in 2020.Application of 700-16-3 The following contents are mentioned in the article:

O-Perfluoropyridin-4-yl group was first installed onto cycloketone oximes as a new electrophore, which was proven to be efficient iminyl radical precursors under photocatalytic and thermal conditions. A range of O-perfluoropyridin-4-yl oximes were successfully utilized in C(sp²)-C(sp³) bond formations of quinoxalin-2(1H)-ones and alkenes, providing facile accesses to a range of functionalized alkylnitriles. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Application of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Application of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Polyfluoroarylation of oxazolones: Access to non-natural fluorinated amino acids was written by Teegardin, Kip A.;Weaver, Jimmie D.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.Electric Literature of C5F5N The following contents are mentioned in the article:

Herein, conditions are provided for the formation and use of the oxazolone enolate for the nucleophilic substitution of highly fluorinated (hetero)arenes, which after unmasking yield highly fluorinated non-natural amino acids and derivatives In addition, the properties and chem. behavior of this new class of amino acids are explored. The utility is demonstrated in the one pot synthesis of medicinally relevant 2-aminohydantoins. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Electric Literature of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Electric Literature of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Decarboxylative Polyfluoroarylation of Alkylcarboxylic Acids was written by Sun, Xiang;Ritter, Tobias. And the article was included in Angewandte Chemie, International Edition in 2021.Computed Properties of C5F5N The following contents are mentioned in the article:

Polyfluoroarenes are useful building blocks in several areas such as drug discovery, materials, and crop protection. Herein, we report the first polyfluoroarylation of aliphatic carboxylic acids via photoredox decarboxylation. The method proceeds with broad substrate scope and high functional group tolerance. Moreover, small complex mols. such as natural products and drugs can be modified by late-stage modification. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Computed Properties of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Computed Properties of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

C-F bond activation by pentamethylcyclopentadienyl-aluminum(I): a combined experimental/computational exercise was written by Kysliak, Oleksandr;Goerls, Helmar;Kretschmer, Robert. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020.Product Details of 700-16-3 The following contents are mentioned in the article:

The reaction of (Cp*Al)₄ with a series of fluoro(hetero)arenes has been investigated and C-F bond activation was observed with perfluorotoluene, pentafluoropyridine as well as 1,2,3,4-tetrafluoro-, pentafluoro- and hexafluorobenzene. The reaction mechanism has been probed by means of DFT calculations and the computational findings are in good agreement with the exptl. observations. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Product Details of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Product Details of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis of some fluorinated thiazolopyridine from pentafluoropyridine and 4-phenylsulfonyl tetrafluoropyridine was written by Ranjbar-Karimi, Reza;Danesteh, Roghayeh;Beiki-Shoraki, Khalil. And the article was included in Arabian Journal of Chemistry in 2019.Computed Properties of C5F5N The following contents are mentioned in the article:

The reaction of pentafluoropyridine and 4-phenylsulfonyl-2,3,5,6-tetrafluoropyridine with difunctional nitrogen and sulfur nucleophiles such as thiourea, thioamide derivatives, and unsym. bidentate nitrogen nucleophiles such as diamino-triazole and amino-imidazole in the presence of sodium carbonate was investigated in this paper. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Computed Properties of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Computed Properties of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Facile Synthesis of 3-Arylindenes by HMPA-Promoted Direct Arylation of Indenes with Aryl Fluorides was written by Ji, Xinfei;Li, Jialu;Wu, Mingsheng;Cao, Song. And the article was included in ACS Omega in 2018.Recommanded Product: 700-16-3 The following contents are mentioned in the article:

A rapid and efficient approach to 3-arylated indenes I (R¹ = H, Et, Br, Ph; R² = H, 4-Me, 3-Me, 3-OMe, etc.) by reactions of indenes with unactivated fluoroarenes with the assistance of LDA and HMPA at room temperature was developed. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Recommanded Product: 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Recommanded Product: 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem