Category: 700-16-3

Pyridylpyrrolido ligand in Ge(II) and Sn(II) chemistry: synthesis, reactivity and catalytic application was written by Pahar, Sanjukta;Sharma, Vishal;Tothadi, Srinu;Sen, Sakya S.. And the article was included in Dalton Transactions in 2021.Recommanded Product: 700-16-3 The following contents are mentioned in the article:

In our previous communication, we have reported the synthesis of a new chlorogermylene (B) featuring a pyridylpyrrolido ligand. This study details the preparation of a series of new germylenes and stannylenes starting from B. A transmetallation reaction between B and SnCl₂ led to the analogous chlorostannylene (1) with the simultaneous elimination of GeCl₂. This is a very unusual example of transmetallation between two elements of the same group. The preparation of 1 via lithiation led to the formation of 2 as a side product, where the ortho C-H bond of the pyridine ring was activated and functionalized with a ⁿBu moiety. Subsequently, B and 1 were used as precursors to generate germylene (4) and stannylene (5) featuring tris(trimethylsilyl)silyl (hypersilyl) moieties. We also prepared tetrafluoropyridyl germylene (6) by reacting 4 with C₅F₅N with the simultaneous elimination of (Me₃Si)₃SiF by utilizing the fluoride affinity of the silicon atom. As there is scarcity of Sn(II) compounds as single-site catalysts, we investigated 5 as a catalyst towards the hydroboration of aldehydes, ketones, alkenes and alkynes. All the compounds have been characterized by single-crystal X-ray diffraction and by state of the art spectroscopic studies. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Recommanded Product: 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Recommanded Product: 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Method of ultrasound-assisted liquid-phase exfoliation to prepare graphene was written by Gu, Xiaoguang;Zhao, Yue;Sun, Kai;Vieira, Carolina L. Z.;Jia, Zhijuan;Cui, Chi;Wang, Zhenjun;Walsh, Annika;Huang, Shaodan. And the article was included in Ultrasonics Sonochemistry in 2019.Name: 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:

Graphene is a two-dimensional material with unique structure and excellent properties. After first being successfully prepared in 2004, it rapidly became a research hotspot in the fields of materials, chem., physics, and engineering. Currently, there are many methods for preparing graphene, such as ball milling method, chem. oxidation-reduction, chem. vapor deposition, and liquid-phase exfoliation. Among these methods, liquid-phase exfoliation is the most important preparation method. In this paper, ultrasound-assisted liquid-phase exfoliation is systematically studied. The output power and frequency of the ultrasonic crusher used in the experiment are 100 W and 20 kHz, resp. Results show that ultrasonic waves can affect the size and thickness distribution of graphene sheets; ultrasound-assisted deoxycholic acid sodium aqueous solution has a good exfoliation effect. In addition, the effects of the 3 liquid-phase systems on preparing graphene are studied, including organic solvent system, aqueous surfactant system, and ionic liquids system; the improvement efforts for ultrasound-assisted liquid-phase exfoliation method are discussed including the exploration of new solvents and optimization of exfoliation process. The application of auxiliary agent-assisted liquid-phase exfoliation method is also discussed. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Name: 2,3,4,5,6-Perfluoropyridine).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 蟺-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 蟽 bonds. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Name: 2,3,4,5,6-Perfluoropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Crystal structures and Hirshfeld surface analysis of a series of 4-O-arylperfluoropyridines was written by Peloquin, Andrew J.;Corley, Cynthia A.;Adas, Sonya K.;Balaich, Gary J.;Iacono, Scott T.. And the article was included in Acta Crystallographica in 2019.Synthetic Route of C5F5N The following contents are mentioned in the article:

Five new crystal structures of perfluoropyridine substituted in the 4-position with phenoxy, 4-bromophenoxy, naphthalen-2-yloxy, 6-bromonaphthalen-2-yloxy, and 4,4′-biphenoxy are reported, viz. 2,3,5,6-tetrafluoro-4-phenoxypyridine, C₁₁H₅F₄NO (I), 4-(4-bromophenoxy)-2,3,5,6-tetrafluoropyridine, C₁₁H₄BrF₄NO (II), 2,3,5,6-tetrafluoro-4-[(naphthalen-2-yl)oxy]pyridine, C₁₅H₇F₄NO (III), 4-[(6-bromonaphthalen-2-yl)oxy]-2,3,5,6-tetrafluoropyridine, C₁₅H₆BrF₄NO (IV), and 2,2′-bis[(perfluoropyridin-4-yl)oxy]-1,1′-biphenyl, C₂₂H₈F₈N₂O₂ (V). The dihedral angles between the aromatic ring systems in I-IV are 78.74 (8), 56.35 (8), 74.30 (7), and 64.34 (19)掳, resp. The complete mol. of V is generated by a crystallog. twofold axis: the dihedral angle between the pyridine ring and adjacent Ph ring is 80.89 (5)掳 and the equivalent angle between the biphenyl rings is 27.30 (5)掳. In each crystal, the packing is driven by C-H路路路F interactions, along with a variety of C-F路路路蟺, C-H路路路蟺, C-Br路路路N, C-H路路路N, and C-Br路路路蟺 contacts. Hirshfeld surface anal. was conducted to aid in the visualization of these various influences on the packing. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Synthetic Route of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 蟺-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 蟽 bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Synthetic Route of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reductive Coupling of (Fluoro)pyridines by Linear 3d-Metal(I) Silylamides of Cr-Co: A Tale of C-C Bond Formation, C-F Bond Cleavage and a Pyridyl Radical Anion was written by Mueller, Igor;Werncke, Christian Gunnar. And the article was included in Chemistry – A European Journal in 2021.SDS of cas: 700-16-3 The following contents are mentioned in the article:

Herein, we disclose the facile reduction of pyridine (and its derivatives) by linear 3d-metal(I) silylamides (M=Cr-Co). This reaction resulted in intermol. C-C coupling to give dinuclear metal(II) complexes bearing a bridging 4,4鈥?dihydrobipyridyl ligand. For iron, we demonstrated that the C-C coupling is reversible in solution, either directly or by reaction with substrates, via a presumed monomeric metal(II) complex bearing a pyridyl radical anion. In the course of this investigation, we also observed that the dinuclear metal(II) complex incorporating iron facilitated the isomerization of 1,4-cyclohexadiene to 1,3-cyclohexadiene as well as equimolar amounts of benzene and cyclohexene. Furthermore, we synthesized and structurally characterized a non-3d-metal-bound pyridyl radical anion. The reactions of the silylamides with perfluoropyridine led to C-F bond cleavage with the formation of metal(II) fluoride complexes of manganese, iron and cobalt along with the homocoupling or reductive degradation of the substrate. In the case of cobalt, the use of lesser fluorinated pyridines led to C-F bond cleavage but no homocoupling. Overall, in this paper we provide insights into the multifaceted behavior of simple (fluoro)pyridines in the presence of moderately to highly reducing metal complexes. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3SDS of cas: 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.SDS of cas: 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Comparison of 渭-nitrido diiron phthalocyanine – H₂O₂ and Fenton systems in transformation of poly- and perfluorinated aromatics does not support the involvement of hydroxyl radicals was written by Colomban, Cedric;Sorokin, Alexander B.. And the article was included in Journal of Coordination Chemistry in 2018.Synthetic Route of C5F5N The following contents are mentioned in the article:

渭-Nitrido diiron tetrabutylphthalocyanine, (FePc^tBu₄)₂N, in combination with H₂O₂ can perform an efficient defluorination of heavily fluorinated aromatics via an oxidative pathway. To check whether hydroxyl radicals might be involved in this reaction we have compared catalytic activities of (FePc^tBu₄)₂N – H₂O₂ and FeSO₄ – H₂O₂ systems in the transformation of five differently fluorinated benzenes, perfluoronaphthalene, pentafluoropyridine, and eight functionalized perfluorinated benzenes. In sharp contrast with (FePc^tBu₄)₂N – H₂O₂ system, all fluorinated benzene derivatives were completely stable in the presence of FeSO₄ and H₂O₂ at 60 掳C during 15 h. Perfluorinated aromatic compounds functionalized with electron-donating or electron-withdrawing groups as well as pentafluoropyridine exhibited very low conversions. These results unambiguously show that Fenton chem. is not responsible for the oxidative defluorination of highly fluorinated aromatic compounds performed by the (FePc^tBu₄)₂N – H₂O₂ system. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Synthetic Route of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Synthetic Route of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A Study of the Reichardt E^NT(30) Parameter using Solvent Molecular Properties Derived from Computation Chemistry and Consideration of the Kamlet and Taft α Scale of Solvent Hydrogen Bond Donor Acidities was written by Waghorne, W. Earle. And the article was included in Journal of Solution Chemistry.Recommanded Product: 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:

Reichardt′s normalized E^NT(30) parameter for solvent polarity has been analyzed in terms of properties of solvent mols. estimated from quantum-mech. calculations of isolated solvent mols. The analyses show that E^NT(30) has a strong dependence on the partial charge on the most pos. hydrogen atom in the solvent mol., reflecting hydrogen bonding at the pendant oxygen atom of the betaine dye used to define the ET(30) scale. There are smaller, and roughly equal, dependences on the dipole moments and quadrupolar amplitudes of the solvent mols. and an inverse dependence on the solvent polarizability. These three dependences reflect the solvent polarity, i.e., the ability to stabilize charge through longer-range interactions. The reason for the inverse dependence on the solvent polarizability is unclear, but a similar dependence was found previously in the anal. of the Kamlet, Abboud and Taft π* scale. The resulting equation for E^NT(30) reproduces the exptl. values for around 160 solvents, representing most classes of organic solvents, with a standard deviation of around 0.07 {E^NT(30) values range from 0 to 1}. The results of the present analyses of E^NT(30) and earlier analyses of π* indicate that, while the α values capture the effect of solvent hydrogen bond donor acidity, it also contains residual dependences on other mol. properties. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Recommanded Product: 2,3,4,5,6-Perfluoropyridine).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Recommanded Product: 2,3,4,5,6-Perfluoropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adsorption characteristics of aromatic pollutants and their halogenated derivatives on bio-based poly (ether-pyridine)s was written by Gomri, Marwen;Abderrazak, Houyem;Chabbah, Taha;Souissi, Radhia;Saint-Martin, Patrice;Casabianca, Herve;Chatti, Saber;Mercier, Regis;Errachid, Abdelhamid;Hammami, Mohamed;Jaffrezic-Renault, Nicole. And the article was included in Journal of Environmental Chemical Engineering in 2020.Reference of 700-16-3 The following contents are mentioned in the article:

In this work, innovative poly(ether pyridine) polymers obtained from bio-based monomers and pentafluoropyridine derivatives were elaborated in order to adsorb aromatic pollutants and their halogenated derivatives These polymers were obtained with satisfactory yields by polycondensation of four pyridinium monomers (resp. based on morpholine, piperazine, dimethylamine and phenol) with isosorbide or bisphenol A. The adsorption efficiency data demonstrate that the poly(ether pyridine) based on isosorbide and morpholine-based monomer (P2) is the more efficient sorbent toward aromatic pollutants and their derivatives Four aromatic pollutants, p-hydroxybenzoic acid, toluic acid, deisopropylatrazine, and 2,4,6-trichlorophenol, were chosen as the adsorbate to investigate the adsorption efficiency, kinetics and isotherms of the poly(ether pyridine) P2. The results demonstrate that the pseudo-second order was the best to describe the adsorption of the four target pollutants by the efficient sorbent P2 with good correlation. The exptl. data of the four target pollutants adsorption were analyzed by Langmuir and Freundlich isotherms. Polymer P2 shows very high affinity (low 1/n value) for p-hydroxybenzoic acid and for 2,4,6-trichlorophenol, compared to other adsorbents. Three consecutive adsorption/desorption cycles toward eight aromatic pollutants were obtained for the efficient sorbent P2. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Reference of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Reference of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Real-time observation of multi-mode vibronic coherence in pentafluoropyridine was written by Kus, J. A.;Hueter, O.;Temps, F.. And the article was included in Journal of Chemical Physics in 2017.Reference of 700-16-3 The following contents are mentioned in the article:

The ultrafast dynamics of pentafluoropyridine in the 1 ¹B₂ (ππ*) electronic state excited at λ_pump = 255 nm was studied by femtosecond time-resolved time-of-flight mass spectrometry and photoelectron imaging spectroscopy. A pronounced, long-lived, and complex periodic modulation of the transient ion yield signal with contributions by four distinct frequency components, 72 cm^-1, 144 cm^-1, 251 cm^-1, and 281 cm^-1, is observed for up to 9 ps. The recorded photoelectron images display a spectral band from the excited 1 ¹B₂ (ππ*) state only in the oscillation maxima; the signal is strongly reduced in the oscillation min. Supported by electronic structure calculations at the RI-SCS-CC2 and XMCQDPT2 levels of theory, the oscillating components of the signal are identified as frequencies of b₁ symmetry coupling modes in a vibronic coherence of the 1 ¹B₂ (ππ*) and 1 ¹A₂ (πσ*) electronic states. The optical excitation initiates regular and periodic wavepacket motion along those out-of-plane modes. In the distorted mol. structure, the initially excited state acquires substantial πσ* character that modulates the transition dipole moment for ionization and results in the observed oscillations. (c) 2017 American Institute of Physics. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Reference of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Reference of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Solving the enigma of weak fluorine contacts in the solid state: a periodic DFT study of fluorinated organic crystals was written by Levina, Elena O.;Chernyshov, Ivan Y.;Voronin, Alexander P.;Alekseiko, Leonid N.;Stash, Adam I.;Vener, Mikhail V.. And the article was included in RSC Advances in 2019.Electric Literature of C5F5N The following contents are mentioned in the article:

The nature and strength of weak interactions with organic fluorine in the solid state are revealed by periodic d. functional theory (periodic DFT) calculations coupled with exptl. data on the structure and sublimation thermodn. of crystalline organofluorine compounds To minimize other intermol. interactions, several sets of crystals of perfluorinated and partially fluorinated organic mols. are considered. This allows us to establish the theor. levels providing an adequate description of the metric and electron-d. parameters of the C-F···F-C interactions and the sublimation enthalpy of crystalline perfluorinated compounds A detailed comparison of the C-F···F-C and C-H···F-C interactions is performed using the relaxed mol. geometry in the studied crystals. The change in the crystalline packing of aromatic compounds during their partial fluorination points to the structure-directing role of C-H···F-C interactions due to the dominant electrostatic contribution to these contacts. C-H···F-C and C-H···O interactions are found to be identical in nature and comparable in energy. The factors that determine the contribution of these interactions to the crystal packing are revealed. The reliability of the results is confirmed by considering the superposition of the electrostatic potential and electron d. gradient fields in the area of the investigated intermol. interactions. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Electric Literature of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Electric Literature of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hydrogen Bond Directed Photocatalytic Hydrodefluorination: Overcoming Electronic Control was written by Khaled, Mohammad B.;El Mokadem, Roukaya K.;Weaver, Jimmie D.. And the article was included in Journal of the American Chemical Society in 2017.Category: pyridine-derivatives The following contents are mentioned in the article:

The photocatalytic C-F functionalization of highly fluorinated arenes is a powerful method for accessing functionalized multifluorinated arenes. The decisive step in the determining regioselectivity in fluorine functionalization is fluoride fragmentation from the radical anion of the multifluorinated arene. To date, the availability of regioisomers has been dictated by the innate electronics of the fluorinated arene, limiting the synthetic utility of the chem. This study investigates the remarkable ability of a strategically located hydrogen bond to transcend the normal regioselectivity of the C-F functionalization event. A significant rate acceleration is addnl. observed for hydrodefluorination of fluorines that can undergo intramol. hydrogen bonds that form 5-8-membered cycles with moderately acidic N-H’s. The hydrogen bond is expected to facilitate the fragmentation not only by bending the C-F bond of the radical anion out of planarity but also by increasing the exothermicity of the fluoride extrusion step through protonation of the naked fluoride. Finally, the synthetic utility of the method is demonstrated in an expedited synthesis of the trifluorinated α-Ph acetic acid derivative required for the com. synthesis of Januvia, an antidiabetic drug. This represents the first synthesis of a com. important multifluorinated arene via a defluorination strategy and is significantly shorter than the current strategy. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Category: pyridine-derivatives).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem