Category: 700-16-3

Reactions of Fluoroalkanes with Mg-Mg Bonds: Scope, sp³C-F/sp²C-F Coupling and Mechanism was written by Coates, Greg;Ward, Bryan J.;Bakewell, Clare;White, Andrew J. P.;Crimmin, Mark R.. And the article was included in Chemistry – A European Journal in 2018.Product Details of 700-16-3 The following contents are mentioned in the article:

Sp³C-F Bonds of fluoroalkanes (7 examples; 1æŽ? 2æŽ?and 3æŽ? undergo addition to a low-valent Mg-Mg species generating reactive organomagnesium reagents. Further reactions with a series of electrophiles results in a net C-F to C-B, C-Si, C-Sn or C-C bond transformation (11 examples, diversity). The new reactivity was exploited in an unprecedented one-pot magnesium-mediated coupling of sp³C-F and sp²C-F bonds. Calculations suggest that the sp³C-F bond activation step occurs by frontside nucleophilic attack of the Mg-Mg reagent on the fluoroalkane. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Product Details of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Product Details of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Syntheses, crystal structures and Hirshfeld surface analyses of (3aR,4S,7R,7aS)-2-(perfluoropyridin-4-yl)-3a,4,7,7a-tetrahydro-4,7-methanoisoindole-1,3-dione and (3aR,4S,7R,7aS)-2-[(perfluoropyridin-4-yl)oxy]-3a,4,7,7a-tetrahydro-4,7-methanoisoindole-1,3-dione was written by Peloquin, Andrew J.;Balaich, Gary J.;Iacono, Scott T.. And the article was included in Acta Crystallographica in 2019.Application of 700-16-3 The following contents are mentioned in the article:

The syntheses and crystal structures of the title compounds, C₁₄H₈F₄N₂O₂ and C₁₄H₈F₄N₂O₃, are reported. In each crystal, the packing is driven by C-H路路路F intertactions, along with a variety of C-H路路路O, C-O路路路蟺, and C-F路路路蟺 contacts. Hirshfeld surface anal. was conducted to aid in the visualization of these various influences on the packing: they showed that the largest contributions to the surface contacts arise from H路路路F/F路路路H interactions, followed by H路路路H and O路路路H/H路路路O. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Application of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Application of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Visible-Light-Driven, Photocatalyst-Free Cascade to Access 3-Cyanoalkyl Coumarins from ortho-Hydroxycinnamic Esters was written by Hu, Yuan-Zhuo;Ye, Zhi-Peng;Xia, Peng-Ju;Song, Dan;Li, Xu-Jie;Liu, Zhi-Lin;Liu, Fang;Chen, Kai;Xiang, Hao-Yue;Yang, Hua. And the article was included in Journal of Organic Chemistry in 2021.Recommanded Product: 700-16-3 The following contents are mentioned in the article:

A visible-light-driven, photocatalyst-free route starting from easily accessed ortho-hydroxycinnamic esters and o-perfluoropyridin-4-yl oximes has been successfully developed to rapidly assemble a wide range of 3-cyanoalkyl coumarins. The process does not require addition of external photocatalysts, exhibiting beneficial features including mild reaction conditions, synthetic simplicity, and excellent substrate compatibility. Extensive mechanistic investigations revealed that the in situ generated phenolate anions served as photosensitizers to drive this photoinduced transformation. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Recommanded Product: 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the �bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the �bonds. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Recommanded Product: 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis of N-substituted sulfonamides containing perhalopyridine moiety as bio-active candidates was written by Hosseini, Raziyeh;Ranjbar-Karimi, Reza;Mohammadiannejad, Kazem. And the article was included in Journal of Fluorine Chemistry in 2020.Name: 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:

A series of N-perhalopyridyl sulfonamide derivatives I [R¹ = H, Me; R² = H, Et, nPr, Bn; R³ = pentafluoropyridin-4-yl, pentachloropyridin-4-yl] as bio-active candidates was synthesized from the reaction of the corresponding aryl sulfonamides with pentafluoro- and pentachloropyridines. Also, unlike aryl sulfonamides, the reaction of sulfamides with pentafluoro- and pentachloropyridines gave unexpected bis-perhalopyridin-4-ylamines II [R⁴ = R⁵ = pentafluoropyridin-4-yl, pentachloropyridin-4-yl]. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Name: 2,3,4,5,6-Perfluoropyridine).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C鈥揌 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Name: 2,3,4,5,6-Perfluoropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dipyrido[1,2-b:3′,4′-e][1,2,4]triazine Scaffolds from Pentafluoropyridine was written by Ranjbar-Karimi, Reza;Darehkordi, Ali;Bahadornia, Fahimeh;Poorfreidoni, Alireza. And the article was included in Journal of Heterocyclic Chemistry in 2018.HPLC of Formula: 700-16-3 The following contents are mentioned in the article:

Annelation reaction between pentafluoropyridine and diaminodihydro substituted pyridine derivatives gave dipyrido[1,2-b:3′,4′-e][1,2,4]triazine systems I (Ar = C₆H₅, 4-MeC₆H₄, 3-O₂NC₆H₄, etc.) as major products arising from the initial nucleophilic substitution of more nucleophilic N-amino group of pyridone ring at 4-position of the pyridine ring followed by intramol. cyclization at 3-position of pyridine ring. Also, 4-aryl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives II were obtained as side products. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3HPLC of Formula: 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ路mol� in pyridine vs. 150 kJ路mol� in benzene). Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. HPLC of Formula: 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Photocatalytic C-F Bond Borylation of Polyfluoroarenes with NHC-boranes was written by Xia, Peng-Ju;Ye, Zhi-Peng;Hu, Yuan-Zhuo;Xiao, Jun-An;Chen, Kai;Xiang, Hao-Yue;Chen, Xiao-Qing;Yang, Hua. And the article was included in Organic Letters in 2020.COA of Formula: C5F5N The following contents are mentioned in the article:

The first photoredox-catalyzed defluoroborylation of polyfluoroarenes with NHC-BH₃ has been facilely achieved at room temperature via a single-electron-transfer (SET)/radical addition pathway. This new strategy makes full use of the advantage of photoredox catalysis to generate the key boryl radical via direct activation of a B-H bond. Good functional group tolerance and high regioselectivity offer this protocol incomparable advantages in preparing a wide array of valuable polyfluoroarylboron compounds Moreover, both computational and exptl. studies were performed to illustrate the reaction mechanism. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3COA of Formula: C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine derivatives are also useful as small-molecule ä¼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.COA of Formula: C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Facile One-Pot Assembly of Push-Pull Imines by a Selective C-F Substitution Process in Aryl Fluorides was written by Anga, Srinivas;Chandra, Shubhadeep;Sarkar, Pallavi;Das, Shubhajit;Mandal, Debdeep;Kundu, Abhinanda;Rawat, Hemant;Schulzke, Carola;Sarkar, Biprajit;Pati, Swapan K.;Chandrasekhar, Vadapalli;Jana, Anukul. And the article was included in European Journal of Organic Chemistry in 2020.Computed Properties of C5F5N The following contents are mentioned in the article:

Herein, we report the synthesis of a series of push-pull imines by considering cyclic diamino substituent at the C-center and fluoroaryl substituent at the N-center. This has been achieved by a selective aromatic nucleophilic substitution of different fluoroarenes by N-H-substituted N-heterocyclic imines (NHIs) at ambient conditions without any addnl. reagent. Solid-state mol. structure anal. reveals the elongation of the central C-N bond of the imine functionality, which is consistent with the push-pull nature of these imines. The push-pull nature of these imines is further validated by computational studies. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Computed Properties of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Computed Properties of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dual Photoredox-/Palladium-Catalyzed Cross-Electrophile Couplings of Polyfluoroarenes with Aryl Halides and Triflates was written by Qin, Jian;Zhu, Shengqing;Chu, Lingling. And the article was included in Organometallics in 2021.Name: 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:

A visible-light photoredox-/Pd-catalyzed cross-electrophile arylation of polyfluoroarenes with aryl halides and triflates in the presence of dialkylamines is reported for the 1st time. This synergistic protocol affords access to fluorodiaryls from easily available starting materials under mild and operationally simple conditions. Mechanistic experiments, including the stoichiometric reactions of a ligated (aryl)Pd complex, Stern-Volmer fluorescence quenching studies, cyclic voltammetry studies, and UV-visible spectroscopy, were performed to elucidate the potential catalytic pathway in this synergistic process. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Name: 2,3,4,5,6-Perfluoropyridine).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of éˆ?8.7 è„?10éˆ? cm3è·¯moléˆ?.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJè·¯moléˆ? in the liquid phase and 140.4 kJè·¯moléˆ? in the gas phase. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C鈥揌 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Name: 2,3,4,5,6-Perfluoropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reagent for Introducing Base-Stabilized Phosphorus Atoms into Organic and Inorganic Compounds was written by Kundu, Subrata;Sinhababu, Soumen;Luebben, Anna V.;Mondal, Totan;Koley, Debasis;Dittrich, Birger;Roesky, Herbert W.. And the article was included in Journal of the American Chemical Society in 2018.Recommanded Product: 700-16-3 The following contents are mentioned in the article:

The cyclic alkyl(amino) carbene (cAAC) stabilized monoanionic P atom as Li phosphinidene [cAACPLi(THF)₂]₂ (1) was isolated as a mol. species and characterized by single crystal x-ray structure anal. Also the structure and bonding of compound 1 was studied by theor. methods. The use of the Li phosphinidene as a P transfer reagent for a wide range of organic and inorganic substrates was studied. Herein, the authors report on the preparation of fascinating compounds containing P-C, P-Si, P-Ge and P-P bonds using a single step with a base stabilized P atom. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Recommanded Product: 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six èŸ?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Recommanded Product: 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Perfluoropyridine: Discovery, Chemistry, and Applications in Polymers and Material Science was written by Gautam, Ritesh;Geniza, Ian;Iacono, Scott T.;Friesen, Chadron M.;Jennings, Abby R.. And the article was included in Molecules in 2022.Application of 700-16-3 The following contents are mentioned in the article:

A review. Perfluoropyridine (PFPy) is an organofluorine compound that has been employed for a variety of applications, from straightforward chem. synthesis to more advanced functions, such as fluorinated networks and polymers. This can be directly attributed to the highly reactive nature of PFPy, especially towards nucleophilic aromatic substitution (SNAr). The aim of this review is to highlight the discovery and synthesis of PFPy, discuss its reactive nature towards SNAr, and to summarize known reports of the utilization and thermal anal. of PFPy containing fluoropolymers and fluorinated network materials. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Application of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the �bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the �bonds. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Application of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem