Category: 700-16-3

Light-Mediated Sulfur-Boron Exchange was written by Panferova, Liubov I.;Dilman, Alexander D.. And the article was included in Organic Letters in 2021.Synthetic Route of C5F5N The following contents are mentioned in the article:

Photochem. organocatalytic substitution of pyridylthio group in alkyl tetrafluoropyridinyl thioethers RS-4-C₅F₄N with bis(catecholato)diboron followed by treatment with pinacol and triethylamine affording pinacol boronic esters RBpin is described. The reaction is promoted by an organic photocatalyst, 2,4,6-tris(diphenylamino)-3,5-difluorobenzonitrile (3DPA2FBN) under irradiation with 400 nm light, and works with primary, secondary, and tertiary sulfides. The electron depleting character of the fluorinated pyridine fragment plays an important role in generating alkyl radicals. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Synthetic Route of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine derivatives are also useful as small-molecule 伪-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Synthetic Route of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis of diheteroaryl sulfides via chemoselective reaction of 4,6-diaminopyrimidine-2(1H)-thione with haloheteroaryl compounds was written by Davodian, Tayebeh;Ranjbar-Karimi, Reza;Mehrabi, Hossein. And the article was included in Chemistry of Heterocyclic Compounds in 2017.Recommanded Product: 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:

A series of substituted diheteroaryl sulfides was synthesized by the reaction of 4,6-diaminopyrimidine-2(1H)-thione with fluoro- and chloroheteroarom. compounds in the presence of Na₂CO₃ in acetonitrile under reflux conditions. The study indicated that 4,6-diaminopyrimidine-2(1H)-thione reacts with fluoro- and chloroheteroarom. compounds chemoselectively as S- rather than N-nucleophile. The structures of the synthesized compounds were confirmed by IR, ¹H, ¹⁹F, and ¹³C NMR spectroscopy, as well as elemental anal. and X-ray structural anal. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Recommanded Product: 2,3,4,5,6-Perfluoropyridine).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ路mol鈭? in pyridine vs. 150 kJ路mol鈭? in benzene). Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C鈥揌 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Recommanded Product: 2,3,4,5,6-Perfluoropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Catalyst-Free Hydrodefluorination of Perfluoroarenes with NaBH₄ was written by Schoch, Timothy D.;Mondal, Mukulesh;Weaver, Jimmie D.. And the article was included in Organic Letters in 2021.Recommanded Product: 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:

An economical means of removing fluorine from various highly fluorinated arenes using NaBH₄ for synthesis of partially fluorinated arenes was presented. The procedure was adapted for different classes of perfluoroarenes. A novel isomer of an emerging class of organic dyes based on the carbazole phthalonitrile motif was succinctly synthesized in two steps from tetrafluorophthalonitrile, demonstrating the utility of the hydrodefluorination procedure. Initial exploration of the dye showed it to be photoactive and capable of facilitating contrathermodynamic styrenoid E/Z isomerization. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Recommanded Product: 2,3,4,5,6-Perfluoropyridine).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Recommanded Product: 2,3,4,5,6-Perfluoropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reactions of pyridin-2-ol, pyridin-3-ol, and pyridin-4-ol with pentafluoro- and pentachloropyridine was written by Ranjbar-Karimi, Reza;Davodian, Tayebeh;Mehrabi, Hossein. And the article was included in Chemistry of Heterocyclic Compounds in 2017.Electric Literature of C5F5N The following contents are mentioned in the article:

Reactions of pentafluoro- and pentachloropyridines with pyridin-2-ol, pyridin-3-ol and pyridin-4-ol are reported. Pyridin-4-ol yields product of attack at the nitrogen atom, while pyridin-3-ol reacts at the oxygen atom. Pyridin-2-ol reacts as an ambident nucleophile, providing a mixture of products I (X = F, Cl) and II arising from attack at both the oxygen and the nitrogen atoms. The structures of compounds were confirmed by IR spectroscopy, ¹H, ¹³C and ¹⁹F NMR spectroscopy, as well as elemental anal. and X-ray crystallog. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Electric Literature of C5F5N).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine derivatives are also useful as small-molecule 伪-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Electric Literature of C5F5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reactions of Fluoroalkanes with Mg-Mg Bonds: Scope, sp³C-F/sp²C-F Coupling and Mechanism was written by Coates, Greg;Ward, Bryan J.;Bakewell, Clare;White, Andrew J. P.;Crimmin, Mark R.. And the article was included in Chemistry – A European Journal in 2018.Product Details of 700-16-3 The following contents are mentioned in the article:

Sp³C-F Bonds of fluoroalkanes (7 examples; 1掳, 2掳 and 3掳) undergo addition to a low-valent Mg-Mg species generating reactive organomagnesium reagents. Further reactions with a series of electrophiles results in a net C-F to C-B, C-Si, C-Sn or C-C bond transformation (11 examples, diversity). The new reactivity was exploited in an unprecedented one-pot magnesium-mediated coupling of sp³C-F and sp²C-F bonds. Calculations suggest that the sp³C-F bond activation step occurs by frontside nucleophilic attack of the Mg-Mg reagent on the fluoroalkane. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Product Details of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Product Details of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Syntheses, crystal structures and Hirshfeld surface analyses of (3aR,4S,7R,7aS)-2-(perfluoropyridin-4-yl)-3a,4,7,7a-tetrahydro-4,7-methanoisoindole-1,3-dione and (3aR,4S,7R,7aS)-2-[(perfluoropyridin-4-yl)oxy]-3a,4,7,7a-tetrahydro-4,7-methanoisoindole-1,3-dione was written by Peloquin, Andrew J.;Balaich, Gary J.;Iacono, Scott T.. And the article was included in Acta Crystallographica in 2019.Application of 700-16-3 The following contents are mentioned in the article:

The syntheses and crystal structures of the title compounds, C₁₄H₈F₄N₂O₂ and C₁₄H₈F₄N₂O₃, are reported. In each crystal, the packing is driven by C-H路路路F intertactions, along with a variety of C-H路路路O, C-O路路路蟺, and C-F路路路蟺 contacts. Hirshfeld surface anal. was conducted to aid in the visualization of these various influences on the packing: they showed that the largest contributions to the surface contacts arise from H路路路F/F路路路H interactions, followed by H路路路H and O路路路H/H路路路O. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Application of 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Application of 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Visible-Light-Driven, Photocatalyst-Free Cascade to Access 3-Cyanoalkyl Coumarins from ortho-Hydroxycinnamic Esters was written by Hu, Yuan-Zhuo;Ye, Zhi-Peng;Xia, Peng-Ju;Song, Dan;Li, Xu-Jie;Liu, Zhi-Lin;Liu, Fang;Chen, Kai;Xiang, Hao-Yue;Yang, Hua. And the article was included in Journal of Organic Chemistry in 2021.Recommanded Product: 700-16-3 The following contents are mentioned in the article:

A visible-light-driven, photocatalyst-free route starting from easily accessed ortho-hydroxycinnamic esters and o-perfluoropyridin-4-yl oximes has been successfully developed to rapidly assemble a wide range of 3-cyanoalkyl coumarins. The process does not require addition of external photocatalysts, exhibiting beneficial features including mild reaction conditions, synthetic simplicity, and excellent substrate compatibility. Extensive mechanistic investigations revealed that the in situ generated phenolate anions served as photosensitizers to drive this photoinduced transformation. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Recommanded Product: 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 蟺-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 蟽 bonds. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Recommanded Product: 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis of N-substituted sulfonamides containing perhalopyridine moiety as bio-active candidates was written by Hosseini, Raziyeh;Ranjbar-Karimi, Reza;Mohammadiannejad, Kazem. And the article was included in Journal of Fluorine Chemistry in 2020.Name: 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:

A series of N-perhalopyridyl sulfonamide derivatives I [R¹ = H, Me; R² = H, Et, nPr, Bn; R³ = pentafluoropyridin-4-yl, pentachloropyridin-4-yl] as bio-active candidates was synthesized from the reaction of the corresponding aryl sulfonamides with pentafluoro- and pentachloropyridines. Also, unlike aryl sulfonamides, the reaction of sulfamides with pentafluoro- and pentachloropyridines gave unexpected bis-perhalopyridin-4-ylamines II [R⁴ = R⁵ = pentafluoropyridin-4-yl, pentachloropyridin-4-yl]. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Name: 2,3,4,5,6-Perfluoropyridine).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C鈥揌 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Name: 2,3,4,5,6-Perfluoropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Site-Selective C(sp³)-H Functionalization of Fluorinated Alkanes Driven by Polar Effects Using a Tungstate Photocatalyst was written by Fukuyama, Takahide;Nishikawa, Tomohiro;Ryu, Ilhyong. And the article was included in European Journal of Organic Chemistry in 2020.Name: 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:

The TBADT-catalyzed C(sp³)-H functionalization of perfluorophenyl- and perfluoroalkyl-substituted alkanes was studied to determine how the fluorous substituents affect site-selectivity. Alkylation of alkyl-substituted perfluorobenzene avoids 伪-C-H bonds, unlike their alkylbenzene counterparts, allowing site-selective functionalization of C-H bonds remote to the aromatic ring. Alkylation of alkanes having a perfluoroalkyl group also avoided 伪-C-H bonds. Radical polar effects in the S_H2 transition states could explain this avoidance of 伪-C-H functionalization. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Name: 2,3,4,5,6-Perfluoropyridine).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ路mol鈭? in pyridine vs. 150 kJ路mol鈭? in benzene). One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Name: 2,3,4,5,6-Perfluoropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis and Photophysical Properties of N-Arylated Diketopyrrolopyrroles was written by Gutkowski, Krzysztof;Azarias, Cloe;Banasiewicz, Marzena;Kozankiewicz, Boleslaw;Jacquemin, Denis;Gryko, Daniel T.. And the article was included in European Journal of Organic Chemistry in 2018.SDS of cas: 700-16-3 The following contents are mentioned in the article:

The N-arylation of diketopyrrolopyrroles with aryl fluorides free of nitro groups was successfully achieved for the first time. Diketopyrrolopyrroles possessing 3,4-dimethoxyphenyl and benzofuryl substituents underwent reaction with, for example, pentafluoropyridine, in the presence of K₂CO₃ in N-methyl-2-pyrrolidone to give the desired products in moderate yields. Their photophys. properties in solution were found not to differ significantly from those of analogous N-alkylated diketopyrrolopyrroles, whereas in contrast to the latter compounds, they were found to possess fluorescence in the solid state. The photophys. properties of all compounds were rationalized by using time-dependent d. functional theory. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3SDS of cas: 700-16-3).

2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C鈥揌 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.SDS of cas: 700-16-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem