Category: 72617-82-4

Application of 72617-82-4, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.72617-82-4, name is 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine, molecular formula is C7H7F3N2O, molecular weight is 192.14, as common compound, the synthetic route is as follows.

Step 3: 8-Hydroxy-2-[6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-2-aza-spiro[4.5]decan-1-one 6-(2,2,2-Trifluoro-ethoxy)-pyridin-3-ylamine (5.11 g, obtained in example 108, step 2) was added to a solution of 4-hydroxy-1-(2-methoxy-ethyl)-cyclohexanecarboxylic acid ethyl ester (5.10 g, obtained in example 2, step 3) in toluene (160 mL).

Statistics shows that 72617-82-4 is playing an increasingly important role. we look forward to future research findings about 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine.

Reference:
Patent; Ackermann, Jean; Brugger, Stephan; Conte, Aurelia; Hunziker, Daniel; Neidhart, Werner; Nettekoven, Matthias; Schulz-Gasch, Tanja; Wertheimer, Stanley; US2011/92512; (2011); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 72617-82-4, name is 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine. This compound has unique chemical properties. The synthetic route is as follows. category: pyridine-derivatives

EXAMPLE 8 1-(2,6-Dichlorobenzoyl)-3-(6-(2,2,2-Trifluoroethoxy)-3-Pyridinyl)Urea 2-(2,2,2-Trifluoroethoxy)-5-aminopyridine (0.5 gram) and 2,6-dichlorobenzoyl isocyanate (0.5 gram) were mixed in ethyl acetate, and the reaction mixture stirred overnight (about 18 hours) at room temperature. Solvent was removed by evaporation and the product residue crystallized from ethyl acetate-hexanes, yield 0.6 gram, m.p., 146-148 C. Calc. for C15 H10 Cl2 F3 N3 O3: C, 44.14; H, 2.47; N, 10.30. Found: C, 44.36; H, 2.54; N, 10.03.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 72617-82-4, 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine.

Reference:
Patent; Eli Lilly and Company; US4173639; (1979); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 72617-82-4, 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 72617-82-4, blongs to pyridine-derivatives compound. name: 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine

EXAMPLE 3 N-[2-(2,2,2-Trifluoroethoxy)-5-pyridyl]-1,3-dithietan-2-imine 8.8 g (0.048 mol) 2-(2,2,2-Trifluoroethoxy)-5-aminopyridine and 3.50 g (0.046 mol) carbon disulphide were combined. Over 5 minutes, 4.65 g (0.046 mol) triethylamine was added, dropwise. The reaction mixture was then stirred at 70 C. for 1 hour. After this 50 ml diethyl ether was added at room temperature. The resulting crystals were separated and dried. 12.0 g (70.6% of theory) triethylammonium N-[2-(2,2,2-trifluoroethoxy)-5-pyridyl]dithiocarbamate was obtained.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,72617-82-4, its application will become more common.

Reference:
Patent; Schering Aktiengesellschaft; US4897415; (1990); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem