Category: 73841-32-4

Adding a certain compound to certain chemical reactions, such as: 73841-32-4, 3-Iodopicolinic acid, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 73841-32-4, blongs to pyridine-derivatives compound. SDS of cas: 73841-32-4

Description 2; Methyl 3-iodo-2-pyridinecarboxylate (D2); A mixture of D1 (3.0 g, 0.012 mol) and c.H2SO4 (2 ml) in MeOH (100 ml) was heated at 65° C. for 18 h. After this period, solvents were evaporated in vacuo and the residue basified with solid NaHCO3. The residue was then extracted with EtOAc (3.x.100 ml). The organic layer was separated, dried (Na2SO4) and concentrated in vacuo to afford the title compound (2.2 g, 70percent). deltaH(CDCl3, 250 MHz) 4.01 (3H, s), 7.13 (1H, dd), 8.29 (1H, dd), 8.64 (1H, dd). MS (ES): C7H61NO2 requires 263. found 264 (MH+)

The synthetic route of 73841-32-4 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Glaxo Group Limited; US2008/312209; (2008); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.73841-32-4, name is 3-Iodopicolinic acid, molecular formula is C6H4INO2, molecular weight is 249.01, as common compound, the synthetic route is as follows.Application In Synthesis of 3-Iodopicolinic acid

Description 2; Methyl 3-iodo-2-pyridinecarboxylate (D2); A mixture of D1 (3.Og, 0.012mol) and CH2SO4 (2ml) in MeOH (100ml) was heated at65°C for 18 h. After this period, solvents were evaporated in vacuo and the residue basified with solid NaHCO3. The residue was then extracted with EtOAc (3x100ml). The organic layer was separated, dried (Na2SO4) and concentrated in vacuo to afford the title compound (2.2g, 70percent). deltaH (CDCI3, 250MHz) 4.01 (3H, s), 7.13 (1 H, dd), 8.29 (1H, dd), 8.64 (1H, dd). MS (ES): C7H6INO2 requires 263; found 264 (MH+)

At the same time, in my other blogs, there are other synthetic methods of this type of compound,73841-32-4, 3-Iodopicolinic acid, and friends who are interested can also refer to it.

Reference:
Patent; GLAXO GROUP LIMITED; WO2007/7018; (2007); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem