Category: 75449-26-2

Pop, Flavia; Melan, Caroline; Danila, Ion; Linares, Mathieu; Beljonne, David; Amabilino, David B.; Avarvari, Narcis published an article in 2014, the title of the article was Hierarchical Self-Assembly of Supramolecular Helical Fibres from Amphiphilic C3-Symmetrical Functional Tris(tetrathiafulvalenes).Name: [2,2′-Bipyridine]-3,3′-diamine And the article contains the following content:

The preparation and self-assembly of the enantiomers of C3-sym. compounds incorporating three tetrathiafulvalene (TTF) residues is reported. The chiral citronellyl and dihydrocitronellyl alkyl chains lead to helical one dimensional stacks in solution Mol. mechanics and dynamics simulations combined with exptl. and theor. CD support the observed helicity in solution These stacks self-assemble to give fibers that have morphologies that depend on the nature of the chiral alkyl group and the medium in which the compounds aggregate. An inversion of macroscopic helical morphol. of the citronellyl compound is observed when compared to analogous 2-methylbutyl chains, which is presumably a result of the stereogenic center being further away from the core of the mol. This composition still allows both morphologies to be observed, whereas an achiral compound shows no helicity. The morphol. of the fibers also depends on the flexibility at the chain ends of the amphiphilic components, as there is not such an apparently persistent helical morphol. for the dihydrocitronellyl derivative as for that prepared from citronellyl chains. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Name: [2,2′-Bipyridine]-3,3′-diamine

The Article related to hierarchical self assembly supramol helix amphiphilic c3 sym tetrathiafulvalene, c3 symmetry, circular dichroism, electronic microscopy, supramolecular chirality, tetrathiafulvalene and other aspects.Name: [2,2′-Bipyridine]-3,3′-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 31, 1990, Kaczmarek, Lukasz; Nantka-Namirski, Pawel published an article.Name: [2,2′-Bipyridine]-3,3′-diamine The title of the article was Synthesis of N-monosubstituted [2,2′-bipyridyl]-3,3′-diamines. And the article contained the following:

The cyclocondensation reaction of 2,2′-bipyridiyl-3,3′-diamine with PhC(:NH)OEt.HCl gave 6-phenyl-5H-dipyrido[3,2-d:2′,3′-f][1,3]diazepine. Alkylation of the latter gave N-benzoyl-N’-alkyl-2,2′-bipyridiyl-3,3′-diamines which upon hydrolysis gave N-alkyl-2,2′-bipyridiyl-3,3′-diamines I [R = Bu, Me2NCH2CH2CH2, [3-(4-chlorophenyl-1-piperazinyl)propyl]]. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Name: [2,2′-Bipyridine]-3,3′-diamine

The Article related to bipyridiyldiamine cyclocondensation benzimidate, dipyridodiazepine phenyl alkylation, diazepine phenyldipyrido alkylation, alkylation phenyldipyridodiazepine, alkylbipyridiyldiamine and other aspects.Name: [2,2′-Bipyridine]-3,3′-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On July 5, 2000, Brunsveld, L.; Zhang, H.; Glasbeek, M.; Vekemans, J. A. J. M.; Meijer, E. W. published an article.Related Products of 75449-26-2 The title of the article was Hierarchical Growth of Chiral Self-Assembled Structures in Protic Media. And the article contained the following:

The location of nine chiral penta(ethylene oxide) side chains at the periphery of a C3-sym. H-bonded extended core gives rise to a thermotropic discotic liquid crystalline material that shows lyotropic phases in polar, protic media f (N,N’,N”-tris{3-[3′-(3,4,5-tris{(2S)-2-(2-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethoxy)propyloxy})benzoylamino]-2,2′-bipyridyl}benzene-1,3,5-tricarbonamide). The mol. stacks self-assemble in a reversible and hierarchical fashion, and specific and subtle solvent-mol. interactions together with the created hydrophobic microenvironment account for an unprecedented stabilization of a preferred handedness of the helical stacks by cooperative intermol. interactions. The presence of either chirality or achirality at the supramol. level in the stacks can be tuned by temperature and solvent as judged from CD spectroscopy. A hierarchical growth of the self-assembly is revealed using a variety of spectroscopic techniques and DSC. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Related Products of 75449-26-2

The Article related to self assembly chiral structure protic media lyotropic liquid crystal, discotic liquid crystal methoxyethoxyethoxyethoxyethoxypropyloxybenzoylaminobipyridylbenzenetricarbonamide and other aspects.Related Products of 75449-26-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On June 30, 2019, Oliveras-Gonzalez, Cristina; Linares, Mathieu; Amabilino, David B.; Avarvari, Narcis published an article.Quality Control of [2,2′-Bipyridine]-3,3′-diamine The title of the article was Large Synthetic Molecule that either Folds or Aggregates through Weak Supramolecular Interactions Determined by Solvent. And the article contained the following:

Weak noncovalent interactions between large disk-like mols. in poorly solvating media generally give fibers where the mols. stack atop one another. A particular chiral spacing group between large aromatic moieties, which usually lead to columnar stacks, in this case gives rise to an intramolecularly folded structure in relatively polar solvents, but in very apolar solvents forms finite aggregates. The mol. that displays this behavior has a C3 sym. benzene-1,3,5-tris(3,3′-diamido-2,2′-bipyridine) (BTAB) core with three metalloporphyrin units appended to it through short chiral spacers. Quite well defined chromophore arrangements are evident by CD spectroscopy of this compound in solution, where clear exciton coupled bands of porphyrins are observed In more polar solvents where the mols. are dispersed, a relatively weak CD signal is observed as a result of intramol. folding, a feature confirmed by mol. modeling. The intramol. folding was confirmed by measuring the CD of a C2 sym. analog. The C3 sym. BTAB cores, that would normally be expected to stack in a chiral arrangement in apolar solvents, show no indication of CD, suggesting that there is no transfer of chirality through it (although the expected planar conformation of the 2,2′-bipyridine unit is confirmed by NMR spectroscopy). The incorporation of the porphyrins on the 3,3′-diamino-2,2′-bipyridine moiety spaced by a chiral unit leaves the latter incapable of assembling through supramol. π-π stacking. Rather, modeling indicates that the three metalloporphyrin units interact thanks to van der Waals interactions, favoring their close interaction over that of the BTAB units. Atomic force microscopy shows that, in contrast to other examples of mols. with the same core, disk like (rather than fibrillar one dimensional aggregates) are favored by the C3 sym. mol. The closed structures are formed through non-directional interlocking of porphyrin rings. The chiral spacer between the rigid core and the porphyrin moieties is undoubtedly important in determining the outcome in polar or less polar solvents, as modeling shows that this joint in the mol. has two favored conformations that render the mol. relatively flat, or convex. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Quality Control of [2,2′-Bipyridine]-3,3′-diamine

The Article related to preparation zinc porphyrin supramol mol folded aggregate, mol structure zinc porphyrin supramol mol folded aggregate, cd spectra zinc porphyrin supramol mol folded aggregate and other aspects.Quality Control of [2,2′-Bipyridine]-3,3′-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Turnbull, William L.; Luyt, Leonard G. published an article in 2018, the title of the article was Amino-Substituted 2,2′-Bipyridine Ligands as Fluorescent Indicators for ZnII and Applications for Fluorescence Imaging of Prostate Cells.Recommanded Product: 75449-26-2 And the article contains the following content:

ZnII concentrations in malignant prostate tissues are much lower than in benign or healthy, suggesting that ZnII levels are a potential biomarker for prostate cancer (PCa). Five 2,2′-bipyridine ligands were synthesized containing amino substituents with varying electron-donating ability for study as fluorescent ZnII indicators. The excited state characteristics of the ligands were explored by UV/visible and fluorescence spectroscopy. 3,3′-Diamino-2,2′-bipyridine (1) was previously shown to be weakly fluorescent as a result of π→π* transitions. The other four ligands have properties consistent with an n→π* intraligand charge transfer excited state. Strongly donating amino and aminophenyl (2 and 4) substituents gave low quantum yields, while weaker donating benzimidazole substituents (6 and 7) gave high quantum yields. Absorption and fluorescence wavelengths underwent bathochromic shifts upon ZnII binding in a majority of cases. Quantum yields drastically increased upon ZnII binding for 1 and 2, but decreased for 4, 6, and 7. Compounds 6 and 7 were incubated with PC-3, DU 145 and BPH-1 cells to determine their ZnII sensing abilities in a biol. system. Weak fluorescence was observed in BPH-1 cells and subsequent incubation with ZnII caused fluorescence intensity to increase. No fluorescence was observed in PCa cell lines. Further study of these ligands may allow for quant. determination of ZnII concentrations in ex vivo tissue samples. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Recommanded Product: 75449-26-2

The Article related to bipyridine ligand fluorescent indicator zinc fluorescence imaging prostate cell, uv/vis spectroscopy, fluorescence spectroscopy, fluorescent probes, prostate cancer, zinc and other aspects.Recommanded Product: 75449-26-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lai, Thanh-Loan; Pop, Flavia; Melan, Caroline; Canevet, David; Salle, Marc; Avarvari, Narcis published an article in 2016, the title of the article was Triggering Gel Formation and Luminescence through Donor-Acceptor Interactions in a C3-Symmetric Tris(pyrene) System.Computed Properties of 75449-26-2 And the article contains the following content:

Straightforward modulation of the gelation, absorption and luminescent properties of a tris(pyrene) organogelator containing a C3-sym. benzene-1,3,5-tricarboxamide central unit functionalized by three 3,3′-diamino-2,2′-bipyridine fragments is achieved through donor-acceptor interactions in the presence of tetracyanoquinodimethane. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Computed Properties of 75449-26-2

The Article related to organogelator gelation uvvis luminescence tcnq donor acceptor, c3 symmetry, donor-acceptor systems, luminescence, organogels, pyrene, Physical Organic Chemistry: Absorption, Emission, Reflection, and Scattering Spectra (Ultraviolet and Visible, Infrared and Fourier Transform Infrared, Raman, Microwave, Photoelectron, Fluorescence, Phosphorescence, etc.) and other aspects.Computed Properties of 75449-26-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Gumbau-Brisa, R.; Hayward, J. J.; Wallis, J. D.; Rawson, J. M.; Pilkington, M. published an article in 2016, the title of the article was Structural insights into the coordination chemistry and reactivity of a 3,3′-bis-imine-2,2′-bipyridine ligand.Recommanded Product: [2,2′-Bipyridine]-3,3′-diamine And the article contains the following content:

The coordination chem. of ligand L8 Schiff-base derived from 6,6′-diamine-2,2′-bipyridine and salicylaldehyde, with Lewis acidic metal ions affords mononuclear [Sn(L9)Cl4] (1) and two paramagnetic dimers [Cu(L9)(sal)]2(ClO4)2, (2) and [Mn(L9)Cl2(EtOH)]2 (3). The x-ray crystal structures of 1-3 reveal a propensity for L8 to undergo metal catalyzed hydrolysis and cyclization to the diazepine ligand L9. Theor. calculations on L8 and a model Sn(IV) complex reveal that coordination to a metal ion weakens the imine bonds, rendering them more susceptible to hydrolysis reactions and/or attack by nucleophiles. In contrast, reaction of L8 with FeCl3 in the presence of base affords the partial hydrolysis product [Fe(L10)2]Cl·CH3CN (4). Tuning the reaction conditions via the addition of a 2nd base slows down the hydrolysis of the ligand sufficiently to afford a few crystals of the μ2-oxo diferric complex (μ-O)[Fe(L8)]2·2CH3CN (5) in which intact L8 coordinates to the Fe(III) in a bis-bidentate manner through a deprotonated salicyl oxygen and a bis-imine nitrogen lone pair, with the nitrogen atoms of its 2,2′-bipyridine remaining uncoordinated. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Recommanded Product: [2,2′-Bipyridine]-3,3′-diamine

The Article related to tin transition metal schiff diaminebipyridine salicylaldehyde diazepine complex preparation, crystal structure tin transition metal schiff diaminebipyridine salicylaldehyde diazepine and other aspects.Recommanded Product: [2,2′-Bipyridine]-3,3′-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On January 9, 2003, Rist, Oystein; Hogberg, Thomas; Holst Lange, Birgitte; Schwartz, Thue W.; Elling, Christian E. published a patent.Computed Properties of 75449-26-2 The title of the patent was Use of metal ion chelates in validating biological molecules as drug targets in test animal models. And the patent contained the following:

The invention discloses the use of chem. compounds or selections of chem. compounds (libraries) of the general Formula R1XFY(R1)GZR1 [F, G = N, O, S, Se, P; X, Y, Z = (un)branched C1-12 alkyl, aryl, heteroaryl, etc.; R1 = ABC; A = coupling or connecting moiety; B = spacer moiety; C = functional group] for in vivo methods for testing or validating the physiol. importance and/or the therapeutic or pharmacol. potential of biol. target mols., notably proteins such as, e.g., receptors and especially 7TM receptors in test animals expressing the biol. target mol. with, notably, a silent, engineered metal ion site. Use of specific metal ion binding sites of a generic nature in specific biol. target mols. such as, e.g. transmembrane proteins wherein the metal ion binding site is capable of forming a complex with a metal ion is also described. Also disclosed are chem. compounds or libraries suitable for use in methods for improving the in vivo pharmacokinetic behavior of metal ion chelates (e.g. the absorption pattern, the plasma half-life, the distribution, the metabolism and/or the elimination of the metal ion chelates). In order to improve the efficacy of the impact of the metal ion chelate on the biol. target mol. after administration of the metal ion chelate in vivo to a test animal, it is advantageous e.g. to increase the period during which the metal ion chelate is in the circulatory system and/or localized at the target. Further disclosed are metal ion-chelating compounds designed to be suitable for use in a target validation process according to the invention, as well as libraries of at least two or more of such metal ion-chelating compounds The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Computed Properties of 75449-26-2

The Article related to metal chelate drug screening target validation, protein target drug screening metal chelate, receptor target drug screening metal chelate, pharmacokinetics metal chelate drug screening and other aspects.Computed Properties of 75449-26-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On April 30, 2013, Zhao, Hongwu; Yue, Yuanyuan; Li, Hailong; Sheng, Zhihui; Yang, Zhao; Meng, Wei published an article.Name: [2,2′-Bipyridine]-3,3′-diamine The title of the article was Asymmetric synthesis of novel axially chiral 2,2′-bipyridine N,N’-dioxides bearing α-amino acid residues and their applications in enantioselective allylation of aromatic aldehydes with allyltrichlorosilane. And the article contained the following:

A series of novel axially chiral 2,2′-bipyridine N,N’-dioxides bearing C1 or C2-symmetry were synthesized by the use of enantiopure α-amino acids as chiral sources. The absolute stereochem. of the axial chirality of these organocatalysts was clearly assigned by CD measurements together with literature protocols. The reactivities and enantioselectivities of these organocatalysts were examined in the reactions of aromatic aldehydes with allyltrichlorosilane, thus providing the desired products with moderate yields and enantioselectivies. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Name: [2,2′-Bipyridine]-3,3′-diamine

The Article related to amino acid bipyridine oxide asym synthesis allylation catalyst, aromatic aldehyde allylchlorosilane enantioselective allylation bipyridine oxide catalyst, benzylic homoallyl alc asym synthesis and other aspects.Name: [2,2′-Bipyridine]-3,3′-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On August 6, 2007, Baysal, Akin; Aydemir, Murat; Durap, Feyyaz; Guemguem, Bahattin; Oezkar, Saim; Yildirim, Leyla Tatar published an article.Formula: C10H10N4 The title of the article was Synthesis and characterizations of 3,3′-bis(diphenylphosphinoamine)-2,2′-bipyridine and 3,3′-bis(diphenylphosphinite)-2,2′-bipyridine and their chalcogenides. And the article contained the following:

New bis(phosphinoamine) and bis(phosphinite) derivatives of 2,2′-bipyridine were prepared through a single step reaction of 3,3′-diamino-2,2′-bipyridine or 3,3′-dihydroxy-2,2′-bipyridine with diphenylchlorophosphine, resp. Their P = E chalcogenide phosphinates (E = O, S, Se) were also prepared All the new compounds were characterized by elemental anal., IR and NMR spectroscopies. The mol. structure of 3,3′-bis(diphenylthiophosphinate)-2,2′-bipyridine was elucidated by single-crystal x-ray crystallog. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Formula: C10H10N4

The Article related to crystal structure bipyridinediyl bisthiophosphinate, mol structure bipyridinediyl bisthiophosphinate, bipyridine phosphinoamino phosphinite preparation oxidation, chalcogenide phosphinate bipyridine preparation and other aspects.Formula: C10H10N4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem