Category: 769-54-0

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 769-54-0, name is 3-Fluoro-4-nitropyridine 1-oxide, the common compound, a new synthetic route is introduced below. Application In Synthesis of 3-Fluoro-4-nitropyridine 1-oxide

To a mixture suspension of 3-fluoro-4-nitropyridine 1-oxide (9.75 g, 61.7 mmol) and methanol (145 mL) was added 28% sodium methoxide methanol solution (11.9 g, 61.7 mmol) with cooling with ice. This mixture was heated to room temperature and stirred for 1 hour at the temperature. The methanol was distilled off under reduced pressure. Water (50 mL) was added to the residue, followed by extracting with chloroform. The organic layer was washed with brine, and anhydrous sodium sulfate was added to dry the layer. After anhydrous sodium sulfate was removed by filtration, the solvent was distilled off under reduced pressure to obtain 3-methoxy-4-nitropyridine 1-oxide (9.54 g; yield, 91%).

The synthetic route of 769-54-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ISHIHARA SANGYO KAISHA, LTD.; KIRIYAMA, Kazuhisa; MATSUMOTO, Masahiro; YOSHIDA, Kotaro; BOLDBAATAR, DamdinSuren; JUKUROGI, Tatsuya; UMEMOTO, Nao; KANI, Tatsuya; MATSUDA, Yoko; TANAKA, Kumiko; KANUMA, Michiko; SHIMADA, Tatsuya; WO2014/98259; (2014); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 769-54-0, name is 3-Fluoro-4-nitropyridine 1-oxide, the common compound, a new synthetic route is introduced below. Application In Synthesis of 3-Fluoro-4-nitropyridine 1-oxide

To a mixture suspension of 3-fluoro-4-nitropyridine 1-oxide (9.75 g, 61.7 mmol) and methanol (145 mL) was added 28% sodium methoxide methanol solution (11.9 g, 61.7 mmol) with cooling with ice. This mixture was heated to room temperature and stirred for 1 hour at the temperature. The methanol was distilled off under reduced pressure. Water (50 mL) was added to the residue, followed by extracting with chloroform. The organic layer was washed with brine, and anhydrous sodium sulfate was added to dry the layer. After anhydrous sodium sulfate was removed by filtration, the solvent was distilled off under reduced pressure to obtain 3-methoxy-4-nitropyridine 1-oxide (9.54 g; yield, 91%).

The synthetic route of 769-54-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ISHIHARA SANGYO KAISHA, LTD.; KIRIYAMA, Kazuhisa; MATSUMOTO, Masahiro; YOSHIDA, Kotaro; BOLDBAATAR, DamdinSuren; JUKUROGI, Tatsuya; UMEMOTO, Nao; KANI, Tatsuya; MATSUDA, Yoko; TANAKA, Kumiko; KANUMA, Michiko; SHIMADA, Tatsuya; WO2014/98259; (2014); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 769-54-0, 3-Fluoro-4-nitropyridine 1-oxide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Product Details of 769-54-0, blongs to pyridine-derivatives compound. Product Details of 769-54-0

Under ice-cooling, 3-fluoro-4-nitropyridine 1-oxide (9.75 g, 61.7 mmol) with the eyeThe mixed suspension of ethanol (145 mL), 28% sodium methoxide methanol solution (11.9 g, 61.7 mmol) was added. The temperature was raised to room temperature, the mixture was stirred at the same temperature for 1 hour. Reduced pressure methanolWas distilled off under Water (50 mL) was added and extracted with chloroform to the residue. The organic layer was washed with saturated brine and dried over anhydrous sodium sulfate. After removing anhydrous sodium sulfate by filtration, the solvent was evaporated under reduced pressure to obtain the desired product (9.54 g, 91% yield).

The synthetic route of 769-54-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ISHIHARA SANGYO KAISHA LIMITED; KIRIYAMA, KAZUHISA; JUKUROGI, TATSUYA; UMEMOTO, NAO; KANI, TATSUYA; MATSUDA, YOKO; TANAKA, KUMINO; (64 pag.)JP2016/11294; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 769-54-0, 3-Fluoro-4-nitropyridine 1-oxide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Product Details of 769-54-0, blongs to pyridine-derivatives compound. Product Details of 769-54-0

Under ice-cooling, 3-fluoro-4-nitropyridine 1-oxide (9.75 g, 61.7 mmol) with the eyeThe mixed suspension of ethanol (145 mL), 28% sodium methoxide methanol solution (11.9 g, 61.7 mmol) was added. The temperature was raised to room temperature, the mixture was stirred at the same temperature for 1 hour. Reduced pressure methanolWas distilled off under Water (50 mL) was added and extracted with chloroform to the residue. The organic layer was washed with saturated brine and dried over anhydrous sodium sulfate. After removing anhydrous sodium sulfate by filtration, the solvent was evaporated under reduced pressure to obtain the desired product (9.54 g, 91% yield).

The synthetic route of 769-54-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ISHIHARA SANGYO KAISHA LIMITED; KIRIYAMA, KAZUHISA; JUKUROGI, TATSUYA; UMEMOTO, NAO; KANI, TATSUYA; MATSUDA, YOKO; TANAKA, KUMINO; (64 pag.)JP2016/11294; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Adding a certain compound to certain chemical reactions, such as: 769-54-0, 3-Fluoro-4-nitropyridine 1-oxide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C5H3FN2O3, blongs to pyridine-derivatives compound. Formula: C5H3FN2O3

Under ice-cooling, 3-fluoro-4-nitropyridine 1-oxide (9.75 g, 61.7 mmol) with the eyeThe mixed suspension of ethanol (145 mL), 28% sodium methoxide methanol solution (11.9 g, 61.7 mmol) was added. The temperature was raised to room temperature, the mixture was stirred at the same temperature for 1 hour. Reduced pressure methanolWas distilled off under Water (50 mL) was added and extracted with chloroform to the residue. The organic layer was washed with saturated brine and dried over anhydrous sodium sulfate. After removing anhydrous sodium sulfate by filtration, the solvent was evaporated under reduced pressure to obtain the desired product (9.54 g, 91% yield).

The synthetic route of 769-54-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ISHIHARA SANGYO KAISHA LIMITED; KIRIYAMA, KAZUHISA; JUKUROGI, TATSUYA; UMEMOTO, NAO; KANI, TATSUYA; MATSUDA, YOKO; TANAKA, KUMINO; (64 pag.)JP2016/11294; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem