Category: 84487-03-6

Reference of 84487-03-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 84487-03-6, name is 6-Chloro-5-nitropyridin-2-amine, molecular formula is C5H4ClN3O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

A mixture of 6-chloro-5-nitropyridin-2-amine(0.26 g, 1.50 mmol), benzylmercaptan (0.19mL, 1.65 mmol), K2CO3 (0.25 g, 1.83 mmol) and DMF (2.1 mL) was stirred at 80 C for 3.5 h. The mixture was poured into water and extracted with CH2CI2 (3×15 mL). The combined organic layers were dried over anhydrous Na2S04 and concentrated. The residue was dissolved in CH2CI2, and the product was precipitated by addition of hexane to give the sub-title compound (0.32 g, 83 %).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 84487-03-6, 6-Chloro-5-nitropyridin-2-amine.

Reference:
Patent; OBLIQUE THERAPEUTICS AB; PELCMAN, Benjamin; SUNA, Edgars; STAFFORD, William; PRIEDE, Martins; (90 pag.)WO2018/146472; (2018); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reference of 84487-03-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 84487-03-6, name is 6-Chloro-5-nitropyridin-2-amine, molecular formula is C5H4ClN3O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

A mixture of 6-chloro-5-nitropyridin-2-amine(0.26 g, 1.50 mmol), benzylmercaptan (0.19mL, 1.65 mmol), K2CO3 (0.25 g, 1.83 mmol) and DMF (2.1 mL) was stirred at 80 C for 3.5 h. The mixture was poured into water and extracted with CH2CI2 (3×15 mL). The combined organic layers were dried over anhydrous Na2S04 and concentrated. The residue was dissolved in CH2CI2, and the product was precipitated by addition of hexane to give the sub-title compound (0.32 g, 83 %).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 84487-03-6, 6-Chloro-5-nitropyridin-2-amine.

Reference:
Patent; OBLIQUE THERAPEUTICS AB; PELCMAN, Benjamin; SUNA, Edgars; STAFFORD, William; PRIEDE, Martins; (90 pag.)WO2018/146472; (2018); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 84487-03-6, name is 6-Chloro-5-nitropyridin-2-amine. This compound has unique chemical properties. The synthetic route is as follows. Application In Synthesis of 6-Chloro-5-nitropyridin-2-amine

REFERENCE EXAMPLE 2 Preparation of the starting compound 6-Amino-2-chloro-3-nitropyridine was allowed to react with ethanethiol to give 6-amino-2-ethylthio-3-nitropyridine (m.p. 131.5-132 C.).

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 84487-03-6, 6-Chloro-5-nitropyridin-2-amine.

Reference:
Patent; Dainippon Pharmaceutical Co., Ltd.; Laboratoire Roger Bellon; US4382937; (1983); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reference of 84487-03-6 ,Some common heterocyclic compound, 84487-03-6, molecular formula is C5H4ClN3O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

General procedure: TAPEHA-Pd (0.015 g) was added to a solution of nitroarenes (1.0 mmol) in EtOH (20 mL). After N2H4 .H2O(4.0 mmol) was added the color of the catalyst was turned to black rapidly in the same way as reducing with NaBH4 . This color change means formation of palladium nanoparticles43 TAPEHA-PdNPs as mentioned above. After being stirred for 20 min at room temperature and atmospheric pressure, the catalyst was removedby ltering and EtOH was removed under a vacuum.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 84487-03-6, 6-Chloro-5-nitropyridin-2-amine, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Genc, Hayriye; Zengin, Mustafa; Kuecuekislamo?lu, Mustafa; Imamoglu, Mustafa; Toplan, Hueseyin Oezkan; Arslan, Mustafa; Turkish Journal of Chemistry; vol. 41; 5; (2017); p. 784 – 792;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem