The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 872-85-5, name is 4-Pyridinecarboxaldehyde. This compound has unique chemical properties. The synthetic route is as follows. Product Details of 872-85-5
EXAMPLE 101 A mixture consisting of 25 g of isonicotine aldehyde, 82 g of ethyl (triphenylphosphoranilidene)acetate and 300 ml of toluene is stirred at 100 C. for 3 hours. After cooling, the deposited crystals are removed by filtration, and the filtrate is concentrated under reduced pressure. A mixture of ethyl acetate and petorleum ether (1:1, 400 ml) is added to the residue, and the mixture is extracted with 500 ml of 5% hydrochloric acid. The aqueous solution portion is extracted with 50 ml of ethyl acetate, followed by neutralization with potassium carbonate and cooling. The deposited crystals are collected by filtration and dried to give 34 g of 3-(4-pyridyl)acrylate as colorless prisms. m.p. 64-66 C.
With the rapid development of chemical substances, we look forward to future research findings about 872-85-5.
Reference:
Patent; Takeda Chemical Industries, Ltd.; US4638000; (1987); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem