Category: 89076-64-2

Zhao, Rui published the artcileSyntheses, structures and properties of cyclometalated iridium(III) complexes based on 2-phenyl-5-nitropyridyl and different strong-field ancillary ligands, HPLC of Formula: 89076-64-2, the publication is Inorganica Chimica Acta (2014), 409(PB), 372-378, database is CAplus.

The reactions of [Ir(5-NO₂-ppy)₂(PPh₃)Cl] (5-NO₂-ppy = 2-phenyl-5-nitropyridyl, PPh₃ = PPh₃, 1) with pseudohalides, replacing the weak π donor Cl^– with strong σ donors and π acceptors, lead to three new Ir(III) cyclometalated complexes [Ir(5-NO₂-ppy)₂(PPh₃)(L)] (L = NCO^–, 2; NCS^–, 3; N₃^–, 4) based on 2-phenylpyridyl (ppy) derivative, PPh₃ and different pseudohalogen strong-field ancillary ligands. 2–4 Are unambiguously characterized and their crystal structures are also determined by x-ray crystallog. The HOMO-LUMO electronic energy gaps of 1–4 estimated from the cyclic voltammetry measurements are comparable with those calculated from the UV-visible absorption spectra, which are both in the order of 3 > 1 > 2 > 4. Also, the electrochem. and photophys. properties of 1–4 show that the introduction of the electron-withdrawing nitro group to the pyridyl ring of the ppy backbone narrows the HOMO-LUMO electronic energy gaps, compared with those of corresponding ppy-containing Ir(III) complexes.

Inorganica Chimica Acta published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C18H28B2O4, HPLC of Formula: 89076-64-2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Shen, Xuan published the artcileNew 2-phenyl-5-nitropyridyl containing iridium(III) cyclometalated complexes: syntheses, structures, electrochemistry and photophysical properties, Application of 5-Nitro-2-phenylpyridine, the publication is Inorganic Chemistry Communications (2011), 14(9), 1511-1515, database is CAplus.

New 2-phenyl-5-nitropyridyl containing iridium(III) cyclometalated complexes ([Ir(5-NO₂-ppy)₂Cl]₂ (1, 5-NO₂-ppy = 2-phenyl-5-nitropyridyl), [Ir(5-NO₂-ppy)₂(PPh₃)Cl] (2, PPh₃ = triphenylphosphine), [Ir(5-NO₂-ppy)₂(pic)] (3, pic = picolinic acid)) were synthesized and unambiguously characterized. The crystal structures of 2 and 3 were determined by x-ray diffraction analyses. The HOMO-LUMO energy gaps of 1–3 estimated by the cyclic voltammetry (CV) show values in the order of 2 > 3 > 1. The UV-visible absorption and the solid photoluminescence (PL) spectra of 1–3 also were measured, exhibiting the changing orders being consistent with that of the HOMO-LUMO energy gaps. Also, the UV-visible absorption spectra of 1–3 show obvious red shifts compared with those of the corresponding 2-phenylpyridyl (ppy) containing Ir(III) complexes ([Ir(ppy)₂Cl]₂, Ir(ppy)₂(PPh₃)Cl and Ir(ppy)₂(pic)) in which no strongly electron-withdrawing nitro groups are introduced to the pyridyl rings of the ppy ligands. Thus, the HOMO-LUMO energy gaps of 1–3 should be narrower than those of [Ir(ppy)₂Cl]₂, Ir(ppy)₂(PPh₃)Cl and Ir(ppy)₂(pic).

Inorganic Chemistry Communications published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C13H10N2S, Application of 5-Nitro-2-phenylpyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lohse, Olivier published the artcileThe palladium-catalyzed Suzuki coupling of 2- and 4-chloropyridines, Name: 5-Nitro-2-phenylpyridine, the publication is Synlett (1999), 45-48, database is CAplus.

The Suzuki coupling of 2- and 4-chloropyridines with arylboronates is successfully performed under Pd(PPh₃)₄ catalysis. Moderate to good yields are obtained with 4-chloropyridines, while 2-chloropyridines give excellent yields. The corresponding pyridine N-oxides react in the same manner. An easy and cheap access to arylpyridines, is thus achieved.

Synlett published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Name: 5-Nitro-2-phenylpyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Nishiwaki, Nagatoshi published the artcileThree components ring transformation affording substituted 5-nitropyridines and 4-nitroanilines, Recommanded Product: 5-Nitro-2-phenylpyridine, the publication is Letters in Organic Chemistry (2006), 3(8), 629-633, database is CAplus.

The ring transformation of 1-methyl-3,5-dinitro-2-pyridone afforded 2-aryl-5-nitropyridines upon treatment with aromatic ketones in the presence of ammonium acetate. In reactions with aliphatic ketones, 2,6-disubstituted 4-nitroanilines could be prepared in addition to 2,3-disubstituted 5-nitropyridines. In these reactions, dinitropyridone behaved as the synthetic equivalent of unstable nitromalonaldehyde.

Letters in Organic Chemistry published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Recommanded Product: 5-Nitro-2-phenylpyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Das, Prasenjit published the artcileAerobic Direct C(sp2)-H Hydroxylation of 2-Arylpyridines by Palladium Catalysis Induced with Aldehyde Auto-Oxidation, COA of Formula: C11H8N2O2, the publication is ACS Catalysis (2016), 6(9), 6050-6054, database is CAplus.

Herein we present a Pd-catalyzed direct C-H hydroxylation of 2-arylpyridines using mol. oxygen (O₂) as the sole oxidant. The key aspects of the method include: (a) the activation of mol. oxygen with a nontoxic and inexpensive aldehyde; (b) an efficient association of the in situ-generated acyl peroxo radical with palladium catalysis; and (c) convenient operating conditions. On the basis of the results obtained in a series of control experiments, a Pd^II/Pd^IV catalytic cycle is implicated for the transformations. Furthermore, the method offers an easy access to a broad range of substituted 2-(pyridin-2-yl)phenols in good isolated yields.

ACS Catalysis published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, COA of Formula: C11H8N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Niu, Luyao published the artcileSynthesis, structure and anticancer activity of three platinum(II) complexes with 2-phenylpyridine derivatives, Category: pyridine-derivatives, the publication is Inorganic Chemistry Communications (2021), 108737, database is CAplus.

Three luminescent Pt(II) complexes, [Pt(5-NO₂-ppy)(H-5-NO₂-ppy)(Cl)] (1), [Pt(2-(2′,4′-dF)-ppy)(H-2-(2′,4′-dF)-ppy)(Cl)] (2), [Pt(2-(3′,5′-dF)-ppy)(H-2-(3′,5′-dF)-ppy)(Cl)] (3) with 2-phenyl-5-nitropyridyl (5-NO₂-ppy), 2-(2,4-difluorophenyl)pyridine (2-(2′,4′-dF)-ppy) and 2-(3,5-difluorophenyl)pyridine(2-(3′,5′-dF)-ppy) were synthesized. FTIR spectroscopy, multinuclear NMR spectroscopy and single-crystal x-ray crystallog. were used to determine their structures. The UV-visible absorption and photoluminescence (PL) spectra of 1–3 were measured. 1–3 Displayed rich photophys. properties with the maximum emission wavelengths at 403-527 nm in the photoluminescence spectra, which demonstrated 1–3 have the potential to become the DNA luminescent probes in living cells. The anticancer activities of these complexes were tested in vitro by MTT assay against four tumor cell lines BGC823, MGC803 (human gastric cancer cell lines), HepG2 (human hepatocellular carcinoma), A549 (human non-small-cell lung cancer cell lines), HL-7702(human normal liver cell line). Moreover, 3 displayed highest cytotoxicity against human gastric cancer cell lines with the values of IC₅₀ at 13.036-26.594μM.

Inorganic Chemistry Communications published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Ramakrishna, Visannagari published the artcileA Zwitterionic Palladium(II) Complex as a Precatalyst for Neat-Water-Mediated Cross-Coupling Reactions of Heteroaryl, Benzyl, and Aryl Acid Chlorides with Organoboron Reagents, Application of 5-Nitro-2-phenylpyridine, the publication is European Journal of Organic Chemistry (2017), 2017(48), 7238-7255, database is CAplus.

In the presence of an (arylimidazoliumquinazolinyl)palladium dichloride complex, arylboronic acids and potassium aryltrifluoroborates underwent Suzuki-Miyaura coupling reactions with aryl, benzylic, and aroyl chlorides in water to yield biaryls, diarylmethanes, and diaryl ketones. Heterocycle-containing biaryls were prepared using either PPh₃ or X-Phos as addnl. ligands.

European Journal of Organic Chemistry published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Application of 5-Nitro-2-phenylpyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Goriya, Yogesh published the artcileRuthenium-Catalyzed C6-Propenylation Reactions of Substituted Pyridine Derivatives: Directed and Direct C-H Activation, Synthetic Route of 89076-64-2, the publication is Chemistry – A European Journal (2012), 18(42), 13288-13292, S13288/1-S13288/158, database is CAplus and MEDLINE.

The complex [(Ru(p-cymene)Cl₂)₂] effects direct C6 propenylation of pyridine derivatives Allyl bromide was found to be optimum for the direct propenylation. E.g., in presence of adamantane-1-carboxylic acid, K₂CO₃, and [(Ru(p-cymene)Cl₂)₂], propenylation of 2-phenylpyridine with allyl bromide gave 67% (E)-I. The expected directed allylation/propenylation of the Ph ring was found to be the predominant pathway with allyl acetate. A one-pot propenylation and arylation (by aryl halides) of 2-arylpyridines was also catalyzed by [(Ru(p-cymene)Cl₂)₂].

Chemistry – A European Journal published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Synthetic Route of 89076-64-2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Yang, Quanlu published the artcileRecyclable palladium catalyst on graphene oxide for the C-C/C-N cross-coupling reactions of heteroaromatic sulfonates, Safety of 5-Nitro-2-phenylpyridine, the publication is Tetrahedron (2015), 71(36), 6124-6134, database is CAplus.

A well-defined heterogeneous palladium catalyst, graphene oxide grafted with palladium chloride (PdCl₂), was prepared and found to be an effective catalyst for a carbon-carbon coupling (C-C bond formation), carbon-nitrogen coupling (C-N bond formation) of heteroaryl sulfonates with aryl boronic acids, terminal alkynes, amines, resp., leading to the desired coupling products in moderate to excellent yields. The catalyst was characterized by XRD, IR, SEM, TEM, XPS and ICP. It is worth noting that this catalyst offers a number of advantages such as high stability and negligible metal leaching. It also retains good activity for at least five successive runs without any addnl. activation treatment, showing a better performance than the well-known com. Pd/C catalysts. This approach would be very useful from a practical viewpoint.

Tetrahedron published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Safety of 5-Nitro-2-phenylpyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Kim, Jiyu published the artcileComplete Switch of Selectivity in the C-H Alkenylation and Hydroarylation Catalyzed by Iridium: The Role of Directing Groups, Name: 5-Nitro-2-phenylpyridine, the publication is Journal of the American Chemical Society (2015), 137(42), 13448-13451, database is CAplus and MEDLINE.

A complete switch in the Cp^*Ir(III)-catalyzed paths between C-H olefination and hydroarylation is crucially dependent on the type of directing groups. This dichotomy in product distribution was correlated to the efficiency in attaining syn-coplanarity of olefin-inserted 7-membered iridacycles. Theor. studies support hypothesis that the degree of flexibility of this key intermediate modulates the β-H elimination, which ultimately affords the observed chemoselectivity.

Journal of the American Chemical Society published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Name: 5-Nitro-2-phenylpyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem