Category: 89076-64-2

Tagata, Tsuyoshi published the artcilePalladium Charcoal-Catalyzed Suzuki-Miyaura Coupling to Obtain Arylpyridines and Arylquinolines, Category: pyridine-derivatives, the publication is Journal of Organic Chemistry (2003), 68(24), 9412-9415, database is CAplus and MEDLINE.

A phosphine ligand, such as PPh₃ or 2-(dicyclohexylphosphino)biphenyl, is essential for the Pd/C-catalyzed Suzuki-Miyaura coupling of halopyridines and haloquinolines, although it has been reported that the reaction of Ph chlorides can be catalyzed by non-prereduced Pd/C without any additives. In the reactions of bromopyridines, bromoquinolines, 2-chloropyridines, and 2-chloroquinolines, PPh₃ was effective enough to provide coupling products in good yields. However, in the reactions of 3-chloropyridine, 4-chloropyridine, and 6-chloroquinoline, sterically hindered 2-(dicyclohexylphosphino)biphenyl was indispensable as a ligand.

Journal of Organic Chemistry published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C5H5BrN2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

El Kadib, Abdelkrim published the artcileCross-Coupling in the Preparation of Pharmaceutically Relevant Substrates using Palladium Supported on Functionalized Mesoporous Silicas, Synthetic Route of 89076-64-2, the publication is ChemCatChem (2011), 3(8), 1281-1285, database is CAplus.

Palladium supported on organically functionalized mesoporous silicas is used to catalyze carbon-carbon cross-coupling reactions including Suzuki-Miyaura reaction and Sonogashira reaction. High yields with low to moderate metal contamination were obtained for various substrates including pyridyl substrates, thiophenes, and pharmaceutical precursors. Products were obtained with palladium loadings that were sufficient to pass muster without further scavenging in the case of Suzuki-Miyaura couplings. The secondary scavenging of products from Sonogashira reaction is necessary.

ChemCatChem published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Synthetic Route of 89076-64-2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Kantak, Abhishek A. published the artcileRegioselective C-H bond amination by aminoiodanes, Category: pyridine-derivatives, the publication is Chemical Communications (Cambridge, United Kingdom) (2015), 51(17), 3574-3577, database is CAplus and MEDLINE.

A new approach for the direct amination of 2-phenylpyridine derivatives using a diphthalimide-iodane and copper triflate has been developed. A series of different 2-phenylpyridine derivatives were aminated with yields up to 88%. Mechanistic investigations indicate that the reaction proceeds via a copper-mediated single electron transfer.

Chemical Communications (Cambridge, United Kingdom) published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Rana, Surjyakanta published the artcileOrgano functionalized graphene with Pd nanoparticles and its excellent catalytic activity for Suzuki coupling reaction, Category: pyridine-derivatives, the publication is Applied Catalysis, A: General (2015), 539-547, database is CAplus.

Synthesis of well distributed palladium nanoparticles (3-7 nm) on organo di-amine functionalized graphene is reported, which demonstrated excellent catalytic activity for Suzuki coupling reaction. Organo functionalized graphene support acted as an excellent host which helped in avoiding “Ostwald ripening” i.e., preventing palladium nanoparticle sintering and because of which the catalyst as a whole showed excellent catalytic activity for Suzuki coupling reaction. The catalytic material was characterized by X-ray diffraction (XRD), Fourier-transfer IR spectroscopy (FTIR), Raman spectra, X-ray photoelectron spectra (XPS), and Scanning electron microscope (SEM), Transmittance electron microscopy (TEM) anal. FT-IR revealed that the organic amine functional group was successfully grafted onto the graphene oxide surface. The formation of palladium nanoparticles was confirmed by XPS techniques. The catalytic activity in the coupling reaction using idobenzene was superb with 100% conversion and 98% yield and also activity remained almost unaltered up to six cycles. Typically, an extremely high turnover frequency of 185,078 h-1 or 3,084.64 min-1 is observed in the C-C Suzuki coupling reaction using organo di-amine functionalized graphene as catalyst. Experiments were also conducted under identical conditions to prove heterogeneity of the catalyst.

Applied Catalysis, A: General published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Pruschinski, Lucas published the artcileSuzuki-Miyaura Cross-Couplings under Acidic Conditions, Safety of 5-Nitro-2-phenylpyridine, the publication is Synthesis (2020), 52(6), 882-892, database is CAplus.

Suzuki-Miyaura reactions with Pd(PPh₃)₄ had carried out using lithium N-phenylsydnone-4-carboxylate as additive, which gave best yields at pH 5.7 in a mixture of acetic acid, water, and sodium carbonate. Reaction parameters such as the Pd source, the solvent, reaction time and temperature, acid, base and carboxylate have been varied and some representative examples of the Suzuki-Miyaura reaction have been examined

Synthesis published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Safety of 5-Nitro-2-phenylpyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Wang, Chao-Yu published the artcilePalladium(II) complexes containing a bulky pyridinyl N-heterocyclic carbene ligand: Preparation and reactivity, HPLC of Formula: 89076-64-2, the publication is Journal of Organometallic Chemistry (2007), 692(18), 3976-3983, database is CAplus.

Coordination chem. of a pyridine imidazole-2-ylidene ligand (pyN-C) with sterically hindered substituents toward Pd(II) metal ions was studied. The Pd carbene complex [(C-pyN-C)Pd(η³-allyl)Cl] (3) was prepared via transmetalation from the corresponding Ag carbene complexes with [ClPd(η³-allyl)]₂. Upon the abstraction of chloride, coordination of pyridinyl N becomes feasible to form [C,N-(pyN-C)Pd(η³-allyl)](BF₄) (4). Ligand substitution reaction of 4 with PPh₃ gave [(C-pyN-C)Pd(PPh₃)(η³-allyl)](BF₄), in which the pyridinyl N donor is substituted by the phosphine. This Pd complex appears to be base sensitive. Treatment of 4 with KOCMe₃ causes decomposition to yield metal nanoparticles. Also, decomplexation of 4 takes place under H atm. to generate the carbene precursor, 1-(6-mesityl-2-picolyl)-3-mesitylimidazolium salt. Nevertheless, the Pd complex 4 shows good catalytic activity on the Suzuki-Miyaura and Mizoroki-Heck reactions.

Journal of Organometallic Chemistry published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C7H4ClIO2, HPLC of Formula: 89076-64-2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Ma, Junjie published the artcileNi-Catalyzed C-H Cyanation of (Hetero)arenes with 2-Cyanoisothiazolidine 1,1-Dioxide as a Cyanation Reagent, Name: 5-Nitro-2-phenylpyridine, the publication is Organic Letters (2021), 23(8), 2868-2872, database is CAplus and MEDLINE.

A nickel-catalyzed C-H cyanation reaction of arenes has been developed using 2-cyanoisothiazolidine 1,1-dioxide as an electrophilic cyanation reagent. Many different directing groups can be used in this cyanation to obtain a series of cyanation products with good yields. Adopting this strategy to introduce a cyano group, natural alkaloid menisporphine was successfully synthesized through cyano group conversion that further proved the practicality of this cyanation method.

Organic Letters published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Name: 5-Nitro-2-phenylpyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Kerric, Gaelle published the artcileUse of polymer-supported phenyltin for the creation of aryl-aryl or aryl-heteroaryl bonds via Stille cross-coupling reactions, Synthetic Route of 89076-64-2, the publication is Journal of Organometallic Chemistry (2009), 695(1), 103-110, database is CAplus.

An insoluble polymer-supported phenyltin reagent was successfully used in Stille cross-coupling reactions with aryl- and heteroaryl halides. Cross-coupling products were isolated in good to high yields with very low contamination by tin and palladium residues after removal of the residual supported organotin halide. The regeneration and recyclability of the supported phenyltin reagent were also examined and proved to be possible, but required palladium cleaning of the grafted polymer to be efficient along 4 cycles when Pd(PPh₃)₄ was used as catalyst.

Journal of Organometallic Chemistry published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Synthetic Route of 89076-64-2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Fenger, Isabelle published the artcileReusable polymer-supported palladium catalysts: an alternative to tetrakis(triphenylphosphine)palladium in the Suzuki cross-coupling reaction, Recommanded Product: 5-Nitro-2-phenylpyridine, the publication is Tetrahedron Letters (1998), 39(24), 4287-4290, database is CAplus.

The Suzuki cross-coupling reaction of a boronic acid and a bromoarom. compound requires palladium catalysis. Almost identical yields were obtained under the usual conditions, with 30 mequivalent of Pd(PPh₃)₄, and with 2 mequiv of a polymer-supported catalyst, which was easily prepared in two steps from Merrifield polymer. Recovery and reuse of the catalyst is easy, and only 0.60% of the initial amount of palladium is lost during a reaction.

Tetrahedron Letters published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, Recommanded Product: 5-Nitro-2-phenylpyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Zafar, Sana published the artcileLinear and non linear optical properties of electron donor and acceptor pyridine moiety: a study by ab initio and DFT methods, COA of Formula: C11H8N2O2, the publication is Canadian Journal of Pure & Applied Sciences (2012), 6(1), 1827-1835, database is CAplus.

The Donor-Acceptor type conjugated mol. structures containing pyridine as a bridge were explored for non linear optical properties. The ab-initio Hartree Fock calculations and D. Functional Theory with B3LYP method were carried out employing 6-31 G basis set. The dipole moments (μ), polarizability (α), 1st hyperpolarizability (β), and HOMO-LUMO energy gap are calculated using the same level of theory. The dependence of the hyperpolarizability of different mol. structure on the nature of donor and acceptor on the pyridine is discussed from MO picture. Of all the mol. systems studied, the mol. system containing nitro as an acceptor and dimethylaniline as a donor has largest value of hyperpolarizability; 49.92 × 10^-30 esu and 164.61 × 10^-30 esu with ab-initio/HF and DFT/B3LYP, resp. The large value of β for the Donor-Acceptor pyridine derivative suggests the potential applications of these mol. systems in the development of non linear materials.

Canadian Journal of Pure & Applied Sciences published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C9H6BrNO, COA of Formula: C11H8N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem