89570-82-1 | Pyridine-derivatives

New learning discoveries about 89570-82-1

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 89570-82-1, 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 89570-82-1, name is 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine. This compound has unique chemical properties. The synthetic route is as follows. Quality Control of 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine

A CEM-designed 10-mL pressure-rated vial was charged with POCl3(2 mL), 3-chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine (211 mg,1mmol), 4-methoxylbenzoic acid or analogous acid (1mmol). The mixture was irradiated in a CEM Discover Focused Synthesiser (150 W, 140C, 200 psi, 15min). The mixture was cooled to room temperature by passing compressed air through the microwave cavity for 2 min. It was poured into cold ice (40 mL) and the formed precipitate filtered. The crude solid was recrystallised from EtOH to give the title compound 2a and others. All the other compounds were synthesised according to the same procedure.

Reference:
Article; Yang, Ming-Yan; Zhai, Zhi-Wen; Sun, Zhao-Hui; Yu, Shu-Jing; Liu, Xing-Hai; Weng, Jian-Quan; Tan, Cheng-Xia; Zhao, Wei-Guang; Journal of Chemical Research; vol. 39; 9; (2015); p. 521 – 523;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine

According to the analysis of related databases, 89570-82-1, the application of this compound in the production field has become more and more popular.

Reference of 89570-82-1, Adding some certain compound to certain chemical reactions, such as: 89570-82-1, name is 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine,molecular formula is C6H5ClF3N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 89570-82-1.

General procedure: The synthetic route of title compounds was outlined in Scheme (1). 2,3-Dichloro-5-(trifluoromethyl)pyridine (7.50mmol) was dissolved in ethanol (300 mL), then hydrazine hydrate (30 mmol) was dropwised under refluxing condition for 72 h to give 3-chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine 1. A CEM designed 10 mL pressure-rated vial was charged with 3-chloro-2-hydrazinyl-5-(trifluoromethyl) pyridine 1 (211 mg, 1 mmol) and aldehyde (1mmol), HOAc (0.1 mmol) in the solution of ethanol at the condition of microwave (15 min, 85C). All the other compounds are synthesized according the procedure.

According to the analysis of related databases, 89570-82-1, the application of this compound in the production field has become more and more popular.

Reference:
Article; Min, Li-Jing; Shi, Yan-Xia; Yang, Ming-Yan; Zhai, Zhi-Wen; Weng, Jian-Quan; Tan, Cheng-Xia; Liu, Xing-Hai; Li, Bao-Ju; Zhang, Yong-Gang; Letters in drug design and discovery; vol. 13; 4; (2016); p. 324 – 328;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Extracurricular laboratory: Synthetic route of 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,89570-82-1, its application will become more common.

Electric Literature of 89570-82-1, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 89570-82-1, name is 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine. A new synthetic method of this compound is introduced below.

Formula () 3- chloro-2-hydrazino-5-trifluoromethyl-pyridine (211mg, 1mmol) shown in ethanol (10ml), acetic acid (0.1mmol), 2- fluorobenzaldehyde (1 mmol of) mixing, Join CEM pressure tank, and then in the microwave synthesizer (150W, 85 , 200psi, 15minutes) under the conditions of work, after the completion of the microwave instrument through which compressed air is cooled to room temperature, filtration, and recrystallized from ethanol to obtain the objective compound of formula (-1) shown chloro-2- (2- (2-fluorophenyl) hydrazine-yl) -5-trifluoromethyl-pyridine, yield 71%.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,89570-82-1, its application will become more common.

Reference:
Patent; Zhejiang University Of Technology; Zhao, Wen; Di, Zhiwen; Yang, Mingyan; Sun, Zhaohui; Liu, Xinghai; Min, Lijing; Shi, Yanxian; Weng, Jianquan; Tan, Chengxia; Li, Baoju; (12 pag.)CN105541706; (2016); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A new synthetic route of 89570-82-1

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 89570-82-1, 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine.

Synthetic Route of 89570-82-1, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 89570-82-1, name is 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine, molecular formula is C6H5ClF3N3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

In 250mL reaction flask, 3-chloro-5- (trifluoromethyl) -2- (2- (2- (trifluoromethyl) phenyl) hydrazino) pyridine 16.92g (0.08mol), 120mL acetonitrile and 9.7g (0.096mol) of triethylamine acid-binding agent, with stirring, a solution of 18.34g (0.088mol) o-trifluoromethyl-benzoyl chloride under ice-cooling.Under ice-cooling, the reaction 1h, TLC monitored the reaction to completion.Amount of ice water was added, a lot of white solid was precipitated, filtered off with suction to give 26.5 g of a white solid, a yield of 93.18%.

Reference:
Patent; Qingdao University of Science and Technology; Xu Liangzhong; Liu Liancai; Sun Jianxin; Cui Huanqi; Wang Minghui; (6 pag.)CN109232550; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A new synthetic route of 89570-82-1

The synthetic route of 89570-82-1 has been constantly updated, and we look forward to future research findings.

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 89570-82-1, name is 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine, the common compound, a new synthetic route is introduced below. Quality Control of 3-Chloro-2-hydrazinyl-5-(trifluoromethyl)pyridine

The synthetic route of 89570-82-1 has been constantly updated, and we look forward to future research findings.