90395-45-2 | Pyridine-derivatives

Analyzing the synthesis route of 90395-45-2

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 90395-45-2, 1-(4-(Pyridin-3-yl)phenyl)ethanone.

Related Products of 90395-45-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 90395-45-2, name is 1-(4-(Pyridin-3-yl)phenyl)ethanone. This compound has unique chemical properties. The synthetic route is as follows.

1-(4-Pyridin-3-ylphenyl)-ethanone (50 g, 253.51 mmole),4-bromo-benzaldehyde (44.67g, 241.44mmole),Add 893 ml of ethanol and stir in the reaction flask.Finally, sodium tert-butoxide (34.77 g, 362.16 mmole) was added and stirred at room temperature.After the reaction has been completed, add 200 ml of deionized water and stir to filter.After filtering the solid with deionized water and methanol, the solid was filtered with 100 ml of deionized water and 200 ml of methanol for 30 minutes.The solid was dried twice to obtain 48 g of pale yellow solid 3-(4-bromophenyl)-1-(4-pyridin-3-ylphenyl)-propanone (3-(4-Bromo-phenyl)-1 -(4-pyridin-3-yl-phenyl)-propanone),The yield was 54.58%.

Reference:
Patent; Yulei Optoelectric Technology Co., Ltd.; Huang Helong; Guo Huangming; Zhao Dengzhi; Lin Qizhen; Zhang Minzhong; (29 pag.)CN109988159; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Sources of common compounds: 1-(4-(Pyridin-3-yl)phenyl)ethanone

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,90395-45-2, its application will become more common.

Reference of 90395-45-2 ,Some common heterocyclic compound, 90395-45-2, molecular formula is C13H11NO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

1-(4-Pyridin-3-ylphenyl)-ethanone (33 g, 166.8 mmole),3,5-Dibromo-benzaldehyde (42.06 g, 159.34 mmole), and 840 ml of ethanol were added to the reaction flask for stirring.Finally, sodium tert-butoxide (22.94 g, 239 mmole) was added and stirred at room temperature.After the reaction has been completed, 200 ml of deionized water is added and stirred for filtration. The solid is filtered and washed with deionized water and methanol. The solid is then filtered with 100 ml of deionized water and 200 ml of methanol for 30 minutes, and repeated twice. Dry the solid to give 55 g of pale yellow solid 3-(3,5-dibromophenyl)-1-(4-pyridin-3-ylphenyl)-acetone(3-(3,5-Dibromo-phenyl)-1-(4-pyridin-3-yl-phenyl)-propanone),The yield was 77.89%.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,90395-45-2, its application will become more common.

Reference:
Patent; E-ray Optoelectronics Technology Co Ltd; Huang, Heh Lung; Guo, Huang Ming; Chao, Teng Chih; Lin, Chi Jen; Chang, Min Jong; (53 pag.)TW2019/30287; (2019); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Sources of common compounds: 1-(4-(Pyridin-3-yl)phenyl)ethanone

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,90395-45-2, its application will become more common.

A new synthetic route of 1-(4-(Pyridin-3-yl)phenyl)ethanone

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 90395-45-2, 1-(4-(Pyridin-3-yl)phenyl)ethanone.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 90395-45-2, name is 1-(4-(Pyridin-3-yl)phenyl)ethanone. A new synthetic method of this compound is introduced below., Recommanded Product: 1-(4-(Pyridin-3-yl)phenyl)ethanone

1-(4-Pyridin-3-ylphenyl)-ethanone (75 g, 380.26 mmole), 3-bromobenzaldehyde (3-bromo) -benzaldehyde) (67g, 362.16mmole), add 1340 ml of ethanol to the reaction flask, and finally add sodium tert-butoxide (52.7 g, 543.23 mmole) at room temperature. After the reaction is complete, add 200 ml. The mixture was filtered with deionized water, and the solid was filtered, washed with deionized water and methanol. The solid was then stirred with 100 ml of deionized water and 200 ml of methanol for 30 minutes. The solid was dried twice to obtain 78 g of pale yellow solid. 3-(3-Bromophenyl)-1-(4-pyridin-3-ylphenyl)-propanone (3-(3-Bromo-phenyl)-1-(4-pyridin-3-yl-phenyl)- Propanone), yield 88.7%

New downstream synthetic route of 90395-45-2

At the same time, in my other blogs, there are other synthetic methods of this type of compound,90395-45-2, 1-(4-(Pyridin-3-yl)phenyl)ethanone, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 90395-45-2, 1-(4-(Pyridin-3-yl)phenyl)ethanone, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, HPLC of Formula: C13H11NO, blongs to pyridine-derivatives compound. HPLC of Formula: C13H11NO

1-(4-pyridin-3-ylphenyl)-ethanone(1-(4-Pyridin-3-yl-phenyl)-ethanone) (75g, 380.26mmole),3-bromobenzaldehyde(3-bromo-benzaldehyde) (67g, 362.16mmole),Add 1340 ml of ethanol and stir in the reaction flask.Finally, sodium tert-butoxide (52.7 g, 543.23 mmole) was added and stirred at room temperature.After the reaction has been completed, add 200 ml of deionized water and stir to filter.After filtering the solid with deionized water and methanol,The solid was then filtered with 100 ml of deionized water and 200 ml of methanol for 30 minutes.The solid was dried twice to obtain 78 g of pale yellow solid 3-(3-bromophenyl)-1-(4-pyridin-3-ylphenyl)-acetone(3-(3-bromo-phenyl)-1-(4-pyridin-3-ylphenyl)propanone),The yield was 88.7%.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,90395-45-2, 1-(4-(Pyridin-3-yl)phenyl)ethanone, and friends who are interested can also refer to it.