Category: 91-02-1

Wang, Yaxin published the artcileTunable System for Electrochemical Reduction of Ketones and Phthalimides, Application of Phenyl(pyridin-2-yl)methanone, the publication is Chinese Journal of Chemistry (2021), 39(12), 3297-3302, database is CAplus.

An efficient, tunable system for electrochem. reduction of ketones R¹C(O)R² (R¹ = Ph, pyridin-2-yl, 4-chlorophenyl, etc.; R² = H, t-Bu, thiophen-2-yl, 3-bromophenyl, etc.) and phthalimides I (R³ = prop-2-en-1-yl, phenoxymethyl, Bn, etc.) at room temperature without the need for stoichiometric external reductants was reported. By utilizing NaN₃ as the electrolyte and graphite felt as both the cathode and the anode, it was able to selectively reduce the carbonyl groups of the substrates to alcs. R¹C(OH)R², pinacols (R¹C(OH)R²)₂, or methylene groups e.g., 13-chloro-4-azatricyclo[9.4.0.0 (3,8)]pentadeca-1(11),3,5,7,12,14-hexaene by judiciously choosing the solvent and an acidic additive. The reaction conditions were compatible with a diverse array of functional groups, and phthalimides I could undergo one-pot reductive cyclization to afford products with indolizidine scaffolds e.g., 10-azatetracyclo[8.7.0.0(2,7).0(12,17)]heptadeca-2,4,6,12(17),13,15-hexaen-11-one. Mechanistic studies showed that the reactions involved electron, proton, and hydrogen atom transfers. Importantly, an N₃/HN₃ cycle operated as a hydrogen atom shuttle, which was critical for reduction of the carbonyl groups to methylene groups e.g., 13-chloro-4-azatricyclo[9.4.0.0 (3,8)]pentadeca-1(11),3,5,7,12,14-hexaene.

Chinese Journal of Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C9H13NO2, Application of Phenyl(pyridin-2-yl)methanone.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Zeng, Kui published the artcileAnomeric Stereoauxiliary Cleavage of the C-N Bond of D-Glucosamine for the Preparation of Imidazo[1,5-a]pyridines, Category: pyridine-derivatives, the publication is Chemistry – A European Journal (2022), 28(29), e202200648, database is CAplus and MEDLINE.

An anomeric stereoauxiliary approach for the synthesis of a wide range of imidazo[1,5-a]pyridines I (R¹ = Me, 2-methylphenyl, pyridin-2-yl, etc.; R² = 4-methoxyphenyl, naphthalen-1-yl, thiophen-2-yl, etc.) after cleaving the C-N bond of D-glucosamine (α-2° amine) from biobased resources was reported . This new approach expands the scope of readily accessible imidazo[1,5-a]pyridines I relative to existing state-of-the-art methods. A key strategic advantage of this approach is that the α-anomer of D-glucosamine enables C-N bond cleavage via a seven-membered ring transition state. By using this novel method, a series of imidazo[1,5-a]pyridine derivatives (>80 examples) was synthesized from 2-acylpyridines (including para-dipyridine ketone) and aldehydes (including para-dialdehyde) R²CHO. Imidazo[1,5-a]pyridine I derivatives containing diverse important deuterated C(sp²)-H and C(sp³)-H bonds were also efficiently achieved.

Chemistry – A European Journal published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C15H10O2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Han, Er-Meng published the artcileMetal-Directed Self-Assembly of {Ti₈L₂} Cluster-Based Coordination Polymers with Enhanced Photocatalytic Alcohol Oxidation Activity, Application In Synthesis of 91-02-1, the publication is Inorganic Chemistry (2022), 61(2), 923-930, database is CAplus and MEDLINE.

Cooperative assembly of the neutral cluster {Ti₈O₅(OEt)₁₈L₂} (L = pyrazine-2,3-dicarboxylic acid) with different metal units of Mn(NO₃)₂, CuCl₂, Zn(OEt)₂, Cd(NO₃)₂, Ce(NO₃)₃, Lu(NO₃)₃, and Lu(NO₃)₂(OEt), or the [Cu₂I₂] cluster, generates a family of Ti-O cluster (TOC)-based coordination polymers. These 1-dimensional (1D) linear structures contain the same {Ti₈L₂} cluster but with variable bridging metal units. The regulation of the heterometal not only affects the chain geometries of the {MTi₈} but also affects the way the 1-dimensional chains are stacked in the crystal lattice. Study of the catalytic activities toward alc. oxidation demonstrated the synergetic effect of combining the metal site and the photosensitive {Ti₈L₂} cluster in the tailored structure. Under light illumination, the {MTi₈} with dual catalytic sites shows greatly enhanced catalytic activity in the selective oxidation of alcs. to aldehydes. Because the compositions and structures of {MTi₈} are highly tunable, this work spotlights the potential of using such metal-bridged multidimensional Ti-oxo materials for cooperative photoredox catalysis for organic transformation.

Inorganic Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Application In Synthesis of 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Zhang, Yin published the artcileDimensional Reduction of Eu-Based Metal-Organic Framework as Catalysts for Oxidation Catalysis of C(sp³)-H Bond, Formula: C12H9NO, the publication is Chinese Journal of Chemistry (2022), 40(4), 480-486, database is CAplus.

Developing new catalysts for highly selectivity and conversion of saturated C(sp³)-H bonds is of great significance. In order to obtain catalysts with high catalytic performance, six Eu-based MOFs with different structural characteristics were obtained by using europium ions and different organic acid ligands, namely Eu-1∼Eu-6. Eu-1, Eu-2 and Eu-3 featured three-dimensional structures, while Eu-4 and Eu-5 featured two-dimensional structures. Differently, a one-dimensional chain structure of Eu-6 was obtained by changing the ligand. All the six MOFs were applied to the catalytic reaction of C(sp³)-H bond, and it was found that the catalytic effect was gradually enhanced with the decrease of dimension and the increase of the size of channels. As expected, Eu-6 showed the highest selectivity (∼99%) and conversion (∼99%). Moreover, catalytic cycling and stability tests showed Eu-6 can be a reliable catalyst.

Chinese Journal of Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C14H10O4S2, Formula: C12H9NO.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Le Saux, Emilien published the artcilePhotochemical Organocatalytic Benzylation of Allylic C-H Bonds, Quality Control of 91-02-1, the publication is Journal of the American Chemical Society (2022), 144(3), 1113-1118, database is CAplus and MEDLINE.

Authors report a radical-based organocatalytic method for the direct benzylation of allylic C-H bonds. The process uses nonfunctionalized allylic substrates and readily available benzyl radical precursors and is driven by visible light. Crucial was the identification of a dithiophosphoric acid that performs two distinct catalytic roles, sequentially acting as a catalytic donor for the formation of photoactive electron donor-acceptor (EDA) complexes and then as a hydrogen atom abstractor. By mastering these orthogonal radical generation paths, the organic catalyst enables the formation of benzylic and allylic radicals, resp., to then govern their selective coupling. The protocol was also used to design a three-component radical process, which increased the synthetic potential of the chem.

Journal of the American Chemical Society published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Quality Control of 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Yu, Han published the artcileVisible-Light-Activated Asymmetric Addition of Hydrocarbons to Pyridine-Based Ketones, Product Details of C12H9NO, the publication is ACS Catalysis (2022), 12(9), 5136-5144, database is CAplus.

A combined system involving Er(III)-based chiral Lewis acid catalysis, Ir(III)-based photoredox catalysis, and bromide-radical-mediated hydrogen atom transfer was disclosed. The introduction of a bulky and nonredox chiral Lewis acid through the photoredox pathway enabled the radical addition process and inhibited the above competitive reactions. The visible-light-promoted catalytic asym. alkylation of heteroaryl-based ketones with diverse hydrocarbons (mainly benzyl) delivered a variety of congested enantioenriched tertiary alcs. (up to 97% yield, 96% enantiomeric excess (ee)).

ACS Catalysis published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C10H18O, Product Details of C12H9NO.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Cao, Dawei published the artcileLight-driven MPV-type reduction of aryl ketones/aldehydes to alcohols with isopropanol under mild conditions, Name: Phenyl(pyridin-2-yl)methanone, the publication is Green Chemistry (2021), 23(19), 7539-7543, database is CAplus.

Herein, a direct light-driven strategy for reducing ketones R¹C(O)R² (R¹ = Ph, pyridin-2-yl, Bu, 1-benzofuran-2-yl, etc.; R² = Ph, pyridin-2-yl, Me, pentyl, etc.) /aldehydes R³CHO (R³ = Ph, 4-(trifluoromethyl)phenyl, 1-benzofuran-2-yl, naphthalen-2-yl, etc.) to alcs. R¹CH(OH)R²/R³OH using isopropanol as the reducing agent and solvent, in the presence of t-BuOLi, under an air atm. at room temperature is developed. This operationally simple light-promoted Meerwein-Ponndorf-Verley (MPV) type reduction can be used to produce various benzylic alc. derivatives as well as applied to bioactive mols. and PEEK model compounds, demonstrating its application potential.

Green Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, Name: Phenyl(pyridin-2-yl)methanone.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Wang, Yue published the artcileA Keggin-type polyoxometalate-based metal-organic complex as a highly efficient heterogeneous catalyst for the selective oxidation of alkylbenzenes, HPLC of Formula: 91-02-1, the publication is Dalton Transactions (2022), 51(6), 2331-2337, database is CAplus and MEDLINE.

The direct oxidation of C-H bonds in organic materials into necessary oxygen containing compounds under mild conditions has attracted increasing attention. A Keggin type polyoxometalate based metal organic complex (MOC), [Cu^II4Cu^I(H₂trz)₄(C₂O₄)(H₂O)₄(H₃PW_11.18Cu^II0.82O₄₀)]·8H₂O (1) (H₃trz = 1,2,4-triazole), was designed and synthesized under hydrothermal conditions, and was structurally characterized by single crystal X-ray diffraction, PXRD, IR spectroscopy, TGA, and XPS. Complex 1 is a 3D 4,6,8-connected architecture derived from [Cu₅(H₂trz)₄(C₂O₄)₂(H₂O)₂]n units and [PW_11.18Cu_0.82O₄₀]^6- anions, which can catalytically oxidize various types of alkylbenzenes. Gas chromatog. anal. showed that complex 1 as a heterogeneous catalyst could effectively catalyze the oxidation of diphenylmethane with 93% conversion and 99% selectivity within 6 h. In addition, the conversion for the catalytic oxidation of ethylbenzene was 96% with 99% selectivity. Compared with some reported catalysts, complex 1 exhibited a better catalytic effect and lower reaction time. Meanwhile, the catalytic oxidation of other benzyl derivatives with complex 1 was also investigated, which indicated that complex 1 possessed excellent catalytic performance.

Dalton Transactions published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C14H20BClO2, HPLC of Formula: 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Xu, Baijie published the artcileA Copper-Containing Polyoxometalate-Based Metal-Organic Framework as an Efficient Catalyst for Selective Catalytic Oxidation of Alkylbenzenes, HPLC of Formula: 91-02-1, the publication is Inorganic Chemistry (2021), 60(7), 4792-4799, database is CAplus and MEDLINE.

A copper-containing polyoxometalate-based metal-organic framework (POMOF), Cu^I12Cl₂(trz)₈[HPW₁₂O₄₀] (HENU-7, HENU = Henan University; trz = 1,2,4-triazole), has been successfully synthesized and well-characterized. In addition, the excellent catalytic ability of HENU-7 has been proved by the selective oxidation of diphenylmethane. Under the optimal conditions, the diphenylmethane conversion obtained over HENU-7 is 96%, while the selectivity to benzophenone is 99%, which outperforms most noble-metal-free POM-based catalysts. Moreover, HENU-7 is stable to reuse for five runs without an obvious loss in activity and also can catalyze the oxidation of different benzylic C-H with satisfactory conversions and selectivities, which implied the significant catalytic activity and recyclability.

Inorganic Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C44H28ClFeN4, HPLC of Formula: 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Xie, Pan published the artcilePhoto-induced oxidative cleavage of C-C double bonds for the synthesis of biaryl methanone via CeCl₃ catalysis, Recommanded Product: Phenyl(pyridin-2-yl)methanone, the publication is Organic & Biomolecular Chemistry (2021), 19(31), 6781-6785, database is CAplus and MEDLINE.

A Ce-catalyzed strategy is developed to produce biaryl methanones via photooxidative cleavage of C-C double bonds at room temperature This reaction is performed under air and demonstrates high activity as well as functional group tolerance. A synergistic Ce/ROH catalytic mechanism is also proposed based on the exptl. observations. This protocol should be the first successful Ce-catalyzed photooxidation reaction of olefins with air as the oxidant, which would provide inspiration for the development of novel Ce-catalyzed photochem. synthesis processes.

Organic & Biomolecular Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C8H7ClO3, Recommanded Product: Phenyl(pyridin-2-yl)methanone.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem