Category: 93-60-7

Ismail, Hani K. published the artcile< Electrodeposition of a mirror zinc coating from a choline chloride-ethylene glycol-based deep eutectic solvent modified with methyl nicotinate>, Related Products of 93-60-7, the main research area is electrodeposition zinc choline chloride ethylene glycol solvet; deep eutectic solvent modified methyl nicotinate.

A number of studies have reported the effects of additives on metal coatings electrochem. deposited from deep eutectic solvents (DESs). However, no previous study has studied the influences of Me nicotinate (MN) as an additive on the electrodeposition of Zn on a Cu substrate from a DES. The results of this study show that MN significantly develops the Zn deposition in this system compared to the corresponding system in its absence. This is the 1st study to date to show that a mirror Zn coating can be obtained on a Cu substrate using such a mechanism. Various electrochem. methods such as cyclic voltammetry, chronocoulometry, and chronoamperometry were used to understand the electrochem. properties of Zn electrolytes in the absence and presence of MN. These experiments found that the redox reaction currents decline when the additive was included in the Zn electrolyte, and that Zn deposition followed an instantaneous nucleation mechanism in the absence of the additive while in its presence the mechanism was closer to that of progressive growth. Further, the current efficiency decreased from 98.99% in the absence of additive to ∼82% as a result of including the additive in the Zn plating bath, according to electrochem. quartz crystal microbalance (EQCM) data. The resultant roughness, thickness and surface morphol. of the deposited Zn were characterized using at. force microscopy, SEM, and x-ray diffraction, indicating that Me nicotinate, as an additive, functions as a highly influential brightener that gave highly homogeneous and flat Zn deposits.

Journal of Electroanalytical Chemistry published new progress about Chronoamperometry. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Related Products of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Elshikh, Mohamed S.; Chen, Tse-Wei; Mani, G.; Chen, Shen-Ming; Huang, Po-Jui; Ali, M. Ajmal; Al-Hemaid, Fahad M.; Al-Mohaimeed, Amal M. published the artcile< Green sonochemical synthesis and fabrication of cubic MnFe2O4 electrocatalyst decorated carbon nitride nanohybrid for neurotransmitter detection in serum samples>, Formula: C7H7NO2, the main research area is neurotransmitter MnFe2o4 electrocatalyst carbon nitride; Bimetal oxides; Graphitic carbon nitride; Hybrid materials; Neurotransmitter detection; Sonochemical synthesis.

The binary nanomaterials and graphitic carbon based hybrid has been developed as an important porous nanomaterial for fabricating electrode with applications in non-enzymic (bio) sensors. We report a fast synthesis of bimetal oxide particles of nano-sized manganese ferrite (MnFe2O4) decorated on graphitic carbon nitride (GCN) via a high-intensity ultrasonic irradiation method for C (30 kHz and 70 W/cm2). The nanocomposites were analyzed by powder X-ray diffraction, XPS, EDS, TEM to ascertain the effects of synthesis parameters on structure, and morphol. The MnFe2O4/GCN modified electrode demonstrated superior electrocatalytic activity toward the neurotransmitter (5-hydroxytryptamine) detection with a high peak intensity at +0.21 V. The appealing application of the MnFe2O4/GCN/GCE as neurotransmitter sensors is presented and a possible sensing mechanism is analyzed. The constructed electrochem. sensor for the detection of 5-hydroxytryptamine (STN) showed a wide working range (0.1-522.6μM), high sensitivity (19.377μA μM-1 cm-2), and nano-molar detection limit (3.1 nM). Moreover, it is worth noting that the MnFe2O4/GCN not only enhanced activity and also promoted the electron transfer rate towards STN detection. The proposed sensor was analyzed for its real-time applications to the detection of STN in rat brain serum, and human blood serum in good satisfactory results was obtained. The results showed promising reproducibility, repeatability, and high stability for neurotransmitter detection in biol. samples.

Ultrasonics Sonochemistry published new progress about Brain. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Formula: C7H7NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Leong, Bi-Xiang; Lee, Jiawen; Li, Yan; Yang, Ming-Chung; Siu, Chi-Kit; Su, Ming-Der; So, Cheuk-Wai published the artcile< A Versatile NHC-Parent Silyliumylidene Cation for Catalytic Chemo- and Regioselective Hydroboration>, Application of C7H7NO2, the main research area is silyliumylidene cation catalyzed regioselective hydroboration carbon dioxide carbonyl compound; pyridine derivative regioselective hydroboration silyliumylidene cation catalyst; formoxyborane regioselective preparation; borate ester regioselective preparation; boryldihydropyridine regioselective preparation.

This study describes the 1st use of a Si(II) complex, NHC-parent silyliumylidene cation complex [(IMe)2SiH]I (1, IMe = :C{N(Me)C(Me)}2) as a versatile catalyst in organic synthesis. Complex 1 (loading: 10 mol %) was shown to act as an efficient catalyst (reaction time: 0.08 h, yield: 94%, TOF = 113.2 h-1; reaction time: 0.17 h, yield: 98%, TOF = 58.7 h-1) for the selective reduction of CO2 with pinacolborane (HBpin) to form the primarily reduced formoxyborane [pinBOC(O)H]. The activity is better than the currently available base-metal catalysts used for this reaction. It also catalyzed the chemo- and regioselective hydroboration of carbonyl compounds and pyridine derivatives to form borate esters and N-boryl-1,4-dihydropyridine derivatives with quant. conversions, resp. Mechanistic studies show that the Si(II) center in complex 1 activated the substrates and then mediated the catalytic hydroboration. Complex 1 was slightly converted into the NHC-borylsilyliumylidene complex [(IMe)2SiBpin]I (3) in the catalysis, which was also able to mediate the catalytic hydroboration.

Journal of the American Chemical Society published new progress about Boranes Role: SPN (Synthetic Preparation), PREP (Preparation) (borate esters, boryldihydropyridines). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Application of C7H7NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zheng, Danqing; Studer, Armido published the artcile< Asymmetric Synthesis of Heterocyclic γ-Amino-Acid and Diamine Derivatives by Three-Component Radical Cascade Reactions>, Safety of 3-(Methoxycarbonyl)pyridine, the main research area is asym synthesis heterocyclic amino acid diamine multicomponent radical cascade; Brønsted acids; amino acids; asymmetric synthesis; photochemistry; radicals.

An enantioselective three-component radical reaction of quinolines or pyridines with enamides and α-bromo carbonyl compounds by dual photoredox and chiral Bronsted acid catalysis is presented. A range of valuable chiral γ-amino-acid derivatives are accessible in high chemo-, regio-, and enantioselectivity from simple, readily available starting materials under mild reaction conditions. Using the same strategy, the asym. synthesis of 1,2-diamine derivatives is also reported. Thus, e.g., 4-methylquinoline + N-vinylacetamide + Me bromoacetate → I (88%, 96:4 er).

Angewandte Chemie, International Edition published new progress about Carbonyl compounds (organic), halo carbonyl compounds Role: RCT (Reactant), RACT (Reactant or Reagent) (quinoline/pyridine + N-vinylacetamide + α-bromo carbonyl compound → γ-amino acid). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Safety of 3-(Methoxycarbonyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tong, Xiaogang; Shi, Bingfei; Liu, Qian; Huo, Yanman; Xia, Chengfeng published the artcile< Retro-biosynthetic construction of corynanthe alkaloid skeletons from rhynchophylline alkaloids>, Quality Control of 93-60-7, the main research area is retro biosynthetic Wagner Meerwein rearrangement rhynchophylline corynanthe alkaloid.

Rhynchophylline alkaloids are bio-synthesized from corynanthe alkaloids via an oxidative rearrangement. We demonstrate here that corynanthe alkaloids could be generated from rhynchophylline alkaloids in a retro-biosynthetic manner via a Wagner-Meerwein rearrangement [e.g., I → II (85%) in presence of TFA in DCM]. A series of corynanthe analogs were afforded with good functional group tolerance and satisfactory yields.

Organic & Biomolecular Chemistry published new progress about Biomimetic synthesis (retro-biomimetic). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Quality Control of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Dai, Q.; Wang, H.; Wang, Y.; Xiao, M.; Jin, H.; Li, M.; Xia, T. published the artcile< Enhancing the sensory attributes and antioxidant properties of snus by mixing it with tea>, Safety of 3-(Methoxycarbonyl)pyridine, the main research area is tea beverage snus antioxidant sensory property.

In the present work, we investigated the chem. and volatile compositions of three tea-containing snus samples, after which their acceptability on the aromatic and taste coordination was evaluated by a professional panel. Results showed that the tea-containing snus samples exhibited better acceptability on the aroma and taste coordination profiles. Dahongpao tea (DT)-containing snus (DT-snus) exhibited the best acceptability of aromatic coordination, whereas the most favorable taste coordination was exhibited by Keemun black tea (KBT)-containing snus (KBT-snus). The antioxidant activity determined by the DPPH and ABTS assays revealed that Lu’an Guapian tea (LGT)-containing snus (LGT-snus) exhibited the highest free-radical scavenging ability. LGT-snus was also found to have the highest content of total polyphenols, amino acids, and caffeine. The highest levels of total flavonoids and soluble sugars were found in DT-snus and KBT-snus, resp. There were 88, 68, and 74 volatiles found in DT-snus, LGT-snus, and KBT-snus, resp., among which, nitrogenous compounds constituted the major category. High levels of nicotine, megastigmatrienone, neophytadiene, nicotyrine, and cotinine, which are the major volatiles in snus, were detected in the tea-containing snus samples. The mixing of tea introduced the flavor profiles of the volatiles present in the original tea into the tea-containing snus samples. Benzaldehyde, β-ionone, hexanoic acid, 3-(Z)-hexenyl ester, pyrazines, and nerolidol from LGT; furfural, benzeneethanol, nerolidol, linalool, and cedrol from DT; and nonanal, geraniol, cis-jasmone, benzenemethanol, and Me salicylate from KBT were found in high concentrations in the corresponding tea-containing snus samples.

International Food Research Journal published new progress about Acids Role: ANT (Analyte), FFD (Food or Feed Use), PRP (Properties), ANST (Analytical Study), BIOL (Biological Study), USES (Uses). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Safety of 3-(Methoxycarbonyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zheng, Yan-Long; Newman, Stephen G. published the artcile< Methyl Esters as Cross-Coupling Electrophiles: Direct Synthesis of Amide Bonds>, Application In Synthesis of 93-60-7, the main research area is methyl ester amine nickel catalyzed cross coupling amide preparation.

Amide bond formation and transition metal-catalyzed cross-coupling are two of the most frequently used chem. reactions in organic synthesis. Recently, an overlap between these two reaction families was identified when Pd and Ni catalysts were demonstrated to cleave the strong C-O bond present in esters via oxidative addition When simple Me and Et esters are used, this transformation provides a powerful alternative to classical amide bond formations, which commonly feature stoichiometric activating agents. Thus far, few redox-active catalysts have been demonstrated to activate the C(acyl)-O bond of alkyl esters, which makes it difficult to perform informed screening when a challenging reaction needs optimization. We demonstrate that Ni catalysts bearing diverse NHC, phosphine, and nitrogen-containing ligands can all be used to activate Me esters and enable their use in direct amide bond formation.

ACS Catalysis published new progress about Aliphatic esters Role: RCT (Reactant), RACT (Reactant or Reagent). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Application In Synthesis of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Vijeta, Arjun; Reisner, Erwin published the artcile< Carbon nitride as a heterogeneous visible-light photocatalyst for the Minisci reaction and coupling to H2 production>, Computed Properties of 93-60-7, the main research area is heterogeneous Minisci hydrogen evolution reaction photocatalyst.

Cyanamide functionalized carbon nitride powder is reported as a photocatalyst for direct Minisci-type coupling of heteroarenes with ethers, alcs., and amides using atm. oxygen as the oxidant at room temperature This mild protocol displays broad substrate scope, good functional group tolerance and the catalyst can be easily isolated and reused for several cycles. It thereby addresses the two major limitations of previously reported photoredox-mediated Minisci reactions: (i) use of expensive and potentially harmful non-recyclable photocatalysts, and (ii) requirement of a stoichiometric amount of strong chem. oxidant. Finally, using platinum as a co-catalyst with the carbon nitride allows this light-mediated reaction to generate two value-added products under an anaerobic atm. – functionalized heteroarenes and H2 fuel.

Chemical Communications (Cambridge, United Kingdom) published new progress about Hydrogen evolution reaction catalysts. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Computed Properties of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tamang, Sem Raj; Singh, Arpita; Bedi, Deepika; Bazkiaei, Adineh Rezaei; Warner, Audrey A.; Glogau, Keeley; McDonald, Corey; Unruh, Daniel K.; Findlater, Michael published the artcile< Polynuclear lanthanide-diketonato clusters for the catalytic hydroboration of carboxamides and esters>, Category: pyridine-derivatives, the main research area is amine preparation; carboxamide hydroboration lanthanide diketonato cluster catalyst; tetramethyl dioxaborolane preparation.

The direct deoxygenation of carboxamides RC(O)N(R1)R2 [R = H, Ph, thiophen-2-yl, naphthalen-2-yl, etc.; R1 = H, Me, Et, (CH2)4CH3, iso-Pr, Ph, benzyl; R2 = H, Me, Et, isopropyl; R1R2 = (CH2)5, (CH2)2O(CH2)2] using earth-abundant lanthanum catalysts in the presence of HBpin presents good to excellent yields with broad substrate scope and functional group/heteroatom tolerance. Moreover, this method is also effective in catalyzing the hydroboration of esters R3C(O)OR4 [R3 = Ph, cyclohexyl, (CH2)6CH3, pyridin-3-yl, etc.; R4 = Me, Et, naphthalen-2-yl, 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl, etc.]. Finally, selective cleavage of the amide group bonds (C-N vs. C-O) could be achieved based on the nature of the nitrogen substituents. Catalytic reduction of carboxamides into their corresponding amines RCH2N(R1)R2 is attractive but extremely challenging transformation, which often meets with limited success; the valuable amine products drive ongoing research in this area.

Nature Catalysis published new progress about Amides Role: RCT (Reactant), RACT (Reactant or Reagent). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Category: pyridine-derivatives.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Tapanyigit, Ozan; Demirkol, Onur; Guler, Ece; Ersatr, Mehmet; Cam, Muhammet Emin; Giray, Elife Sultan published the artcile< Synthesis and investigation of anti-inflammatory and anticonvulsant activities of novel coumarin-diacylated hydrazide derivatives>, Product Details of C7H7NO2, the main research area is coumarin diacylated hydrazide derivative anticonvulsant anti inflammatory.

A number of novel coumarin derivatives synthesized by the reaction of 3-carbonyl chloride coumarin with some substituted aryl acid hydrazides to investigate their anti-inflammatory and anticonvulsant activities. Carrageenan (0.1 mL of 1%, w/v) was injected subplantarly in the right paw of rats to induce an acute model of inflammation. Anti-inflammatory efficacy was evaluated for 5 h at 3 different dosages 5, 10, 25 mg/kg. After that, the changes in the level of paw edema volumes and percentage inhibition of all groups were observed and the most effective coumarin derivative was found as N′-(2-hyroxybenzoyl)-2-oxo-2H-chromene-3-carbohydrazide. In addition, N′-(2-oxo-2H-chromene-3-carbonyl)nicotinohydrazide, (E)-N′-(3-(4-hydroxyphenyl)acryloyl)-2-oxo-2H-chromene-3-carbohydrazide, and N′-(5-amino-2-hydroxybenzoyl)-2-oxo-2H-chromone-3-carbohydrazide showed their anti-inflammatory effects in a dose-dependent manner. On the other hand, pentylenetetrazole (PTZ, 80 mg/kg, i.p.)-induced seizure model was used to investigate the anticonvulsant activities of six newly synthesized coumarin derivatives in mice. Hybrid compound of salicylic acid hydrazide and 3-carbonyl chloride coumarin was found the most promising anticonvulsant agent among all treatment groups according to the onset of seizure and survival rate. Moreover, (E)-N′-cinnamoyl-2-oxo-2H-chromene-3-carbohyrazide and (E)-N′-(3-(4-hyroxyphenyl)acryloyl)-2-oxo-2H-chromene-3-carbohydrazide has potential anticonvulsant efficiency in low doses (30 mg/kg). The anticonvulsant effect of these coumarin derivatives may be through enhanced GABA-mediated inhibition in the brain.

Arabian Journal of Chemistry published new progress about Anti-inflammatory agents. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Product Details of C7H7NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem