Category: 93-60-7

Hu, Yongke; Xia, Jiawei; Li, Jin; Li, Huaju; Li, Yanxing; Li, Shaozhong; Duanmu, Chuansong; Li, Bindong; Wang, Xin published the artcile< Direct oxidative esterification of alcohols catalyzed by a nitrogen-doped carbon black-supported PdBi bimetallic catalyst under ambient conditions>, Electric Literature of 93-60-7, the main research area is PdBi bimetallic catalyzed oxidative esterification alc; aryl ester preparation PdBi bimetallic catalyzed oxidative esterification.

A highly efficient nitrogen-doped carbon black (NCB)-supported PdBi alloy nanocatalyst has been fabricated via a facile coredn. wet chem. approach. The optimal PdBi/NCB shows outstanding catalytic performance with broad substrate scope, good functional group tolerance towards direct oxidative esterification of alcs. under mild conditions in a heterogeneous catalytic system with air as the sole oxidant. A variety of benzylic and allylic alcs. were smoothly reacted with methanol and even with long-chain aliphatic alcs., providing desired esters in good to excellent yields. Moreover, the as-prepared catalyst is easily recycled and can be reused at least five times without a significant loss of catalytic activity. Superior catalytic activity is mainly attributable to the unique structure of the catalyst, including synergetic electronic effect between Pd and Bi, as well as modulated surface character by acidification and N doping for better active components’ anchoring and dispersion, as well as reactants’ adsorption. This study provides a facial, practical, eco-friendly and efficient catalytic system for oxidative esterification of alcs. and shows promising prospect in industrial production

Journal of Materials Science published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Electric Literature of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zhang, Jing; Han, Fu-She published the artcile< Pd-Catalyzed Aerobic Oxidative Heck Cross-Coupling for the Straightforward Construction of Indole δ-Lactams>, Related Products of 93-60-7, the main research area is indolyl amide palladium catalyst oxidative Heck coupling regioselective hetereocyclization; fused indolyl lactam preparation; Catalysis; Chemistry; Organic Chemistry.

A co-ligand-prompted Pd-catalyzed 6-exo-trig intramol. cyclization of indolyl amides via the aerobic oxidative Heck cross-coupling. The method provided a general and efficient way for the construction of [6.5.6]-tricyclic indole δ-lactams. A mechanistic study suggests that a Pd(I)/Pd(III) catalytic cycle should be responsible for effective coupling, which represents a mechanistically alternative pathway when compared with the Pd(0)/Pd(II) cycle proposed for other related coupling reactions.

iScience published new progress about Alkenes Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Related Products of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xiong, Yun; Zhang, Pangzhen; Luo, Jiaqian; Johnson, Stuart; Fang, Zhongxiang published the artcile< Effect of processing on the phenolic contents, antioxidant activity and volatile compounds of sorghum grain tea>, Application of C7H7NO2, the main research area is Sorghum tea phenol antioxidant volatile compound.

Sorghum grain is rich in phenolic compounds and may be used to develop functional tea beverages. This work investigated the effect of processing techniques on the phenolic contents, antioxidant activity, and volatile compounds of a white color sorghum (Liberty) grain tea. Significant (P ≤ 0.05) increase of total phenolic content, total flavonoid content and condensed tannin content were observed during the processing, whereas the antioxidant activity was not statistically enhanced. A total of 63 volatile compounds were detected including 5 alcs., 13 alkanes, 2 aldehydes, 2 carboxylic acids, 15 esters, 4 ketones, 3 pyrazines and 1 phenylenediamine, which were affected by the processing techniques. The sorghum tea made from powder form infusion had more abundant volatile compounds compared to whole grain form infusion. The findings of this research have potential to expand human consumption of sorghum grain in the new form of grain tea.

Journal of Cereal Science published new progress about Alcohols Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Application of C7H7NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Jeon, Jinwon; He, Yu-Tao; Shin, Sanghoon; Hong, Sungwoo published the artcile< Visible-Light-Induced ortho-Selective Migration on Pyridyl Ring: Trifluoromethylative Pyridylation of Unactivated Alkenes>, COA of Formula: C7H7NO2, the main research area is phosphine oxide pyridinyl preparation; pyridinium alkenyloxy alkenylamino preparation trifluoromethylation phosphinylation regioselective migration; fluoroalkyl functionalized pyridine preparation; alkenes; heterocycles; photochemistry; radicals; reaction mechanisms.

The photocatalyzed ortho-selective migration on a pyridyl ring has been achieved for the site-selective trifluoromethylative pyridylation of unactivated alkenes. The overall process was initiated by the selective addition of a CF3 radical to the alkene moiety of N-(alkenyloxy)pyridinium salts I [X = O, Z = (CH2)3, R1 = H, 2-Me, 3-MeO2C, 4-Ph, etc., R2 = H, Me; X = O, Z = CH2, CH2CH2, (CH2)4, R1 = 4-MeO2C, R2 = H; X = NTs, Z = CH2, CH2CH2, R1 = H, 4-MeO2C, R2 = H; etc.] to provide a nucleophilic alkyl radical intermediate, which enabled an intramol. endo addition exclusively to the ortho-position of the pyridinium salt to afford the corresponding functionalized pyridines II. Both secondary and tertiary alkyl radicals were well-suited for addition to the C2-position of pyridinium salts to ultimately provide synthetically valuable C2-fluoroalkyl functionalized pyridines. Moreover, the method was successfully applied to the reaction with P-centered radicals. The utility of this transformation was further demonstrated by the late-stage functionalization of complex bioactive mols.

Angewandte Chemie, International Edition published new progress about Alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, COA of Formula: C7H7NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Timmer, Brian J. J.; Kravchenko, Oleksandr; Liu, Tianqi; Zhang, Biaobiao; Sun, Licheng published the artcile< Off-Set Interactions of Ruthenium-bda Type Catalysts for Promoting Water-Splitting Performance>, COA of Formula: C7H7NO2, the main research area is ruthenium catalyst water splitting performance catalytic activity; homogeneous catalysis; kinetics; noncovalent interactions; ruthenium; water splitting.

O-O bond formation with Ru(bda)L2-type catalysts is well-known to proceed through a bimol. reaction pathway, limiting the potential application of these catalysts at low concentrations Herein, we achieved high efficiencies with mononuclear catalysts, with TOFs of 460±32 s-1 at high catalyst loading and 31±3 s-1 at only 1 μM catalyst concentration, by simple structural considerations on the axial ligands. Kinetic and DFT studies show that introduction of an off-set in the interaction between the two catalytic units reduces the kinetic barrier of the second-order O-O bond formation, maintaining high catalytic activity even at low catalyst concentrations The results herein furthermore suggest that π-π interactions may only play a minor role in the observed catalytic activity, and that asymmetry can also rationalize high activity observed for Ru(bda)(isoq)2 type catalysts and offer inspiration to overcome the limitations of 2nd order catalysis.

Angewandte Chemie, International Edition published new progress about Bond formation. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, COA of Formula: C7H7NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Yakovlev, Ivan A.; Mikhailov, Artem A.; Eremina, Julia A.; Klyushova, Lyubov S.; Nadolinny, Vladimir A.; Kostin, Gennadiy A. published the artcile< Nitric oxide release and related light-induced cytotoxicity of ruthenium nitrosyls with coordinated nicotinate derivatives>, Application In Synthesis of 93-60-7, the main research area is synthesis ruthenium nitrosyl nicotinate complex nitric oxide release; ruthenium nitrosyl nicotinate complex photoinduced cytotoxicity.

The synthetic approaches for the preparation of trans(NO,OH)-cis(NO2,NO2)-[RuNO(L)2(NO2)2OH], where L = Et nicotinate (1) and Me nicotinate (2), are reported. The structures of the complexes were characterized by x-ray diffraction and analyzed by Hirshfeld surface anal. Both compounds show a nitric oxide release reaction under 445 or 532 nm irradiation of DMSO solutions, which was studied by combined UV-visible- (UV-visible), IR- (IR), and EPR spectroscopy and d. functional theory (DFT) calculations The charge transfer from the OH-Ru-NO chain and nitrite ligands to the antibonding orbitals of Ru-NO is responsible for the photo-cleavage of the ruthenium-nitrosyl bond. The elimination of NO leads to a side reaction, the protonation of the parent hydroxyl compound The cytotoxicity and photo-induced cytotoxicity investigations of both compounds on the breast adenocarcinoma cell line MCF-7 reveal that (1) and (2) are cytotoxic with IC50 values of 27.5 ± 2.8μM and 23.3 ± 0.3μM, resp. Also, (1) shows an increase of the toxicity after light irradiation by 7 times (IC50 = 4.1 ± 0.1), which makes it a prominent target for deeper biol. investigations.

Dalton Transactions published new progress about Antitumor agents. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Application In Synthesis of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ma, Yulu; Tang, Huaijun; Dong, Xueyan; Wang, Kaimin; Liu, Manhong; Wang, Yuna published the artcile< A dual-functional 3D coordination polymer as a luminescent sensor for acetone in an aqueous medium and detecting the temperature>, Safety of 3-(Methoxycarbonyl)pyridine, the main research area is cadmium carboxybenzylcarboxypyridinium pyridinylethane preparation luminescent sensor acetone; crystal structure cadmium carboxybenzylcarboxypyridinium pyridinylethane coordination polymer.

A novel coordination polymer, {[Cd4(Ccbp)3(dpe)4·4H2O]·(ClO4)5·4H2O} (1) (Ccbp = 3-carboxy-1-(3-carboxybenzyl)pyridin-1-ium, dpe = 1,2-di(pyridin-4-yl)ethane), was synthesized under hydrothermal conditions by a zwitterionic organic ligand and dipyridine ligand, and was fully characterized. Coordination polymer 1 with a pyridine cation basic skeleton can be used as the 1st potential dual-function luminescence sensing material for the selective, sensitive and recyclable sensing of acetone mols. in aqueous phase and for the quant. detection of ultra-low temperatures of 10 to 70 K.

Inorganic Chemistry Communications published new progress about Crystal structure. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Safety of 3-(Methoxycarbonyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mentana, Annalisa; Camele, Ippolito; Mang, Stefania M.; De Benedetto, Giuseppe E.; Frisullo, Salvatore; Centonze, Diego published the artcile< Volatolomics approach by HS-SPME-GC-MS and multivariate analysis to discriminate olive tree varieties infected by Xylella fastidiosa>, Synthetic Route of 93-60-7, the main research area is HSSPME GCMS multivariate analysis volatile olive tree Xylella infection; HS-SPME-GC-MS; Xylella fastidiosa; multivariate analysis; olive tree; volatiles.

Xylella fastidiosa (Xf) is a pathogenic bacterium that causes diseases in olive trees. Therefore, anal. methods for both the characterization of the host/pathogen interaction and infection monitoring are needed. Volatile organic compounds (VOCs) are emitted by plants relate to their physiol. state, therefore VOCs monitoring can assist in detecting stress or infection states before visible signs are present. In this work, the headspace-solid phase microextraction-gaschromatog.-mass spectrometry (HS-SPME-GC-MS) technique was used for the first time to highlight VOCs differences between healthy and Xf-infected olive trees. VOCs from olive tree twig samples were extracted and analyzed by HS-SPME-GC-MS, and hence identified by comparing the exptl. linear retention indexes with the reference values and by MS data obtained from NIST library. Data were processed by principal component anal. (PCA) and anal. of variance (ANOVA). The HS-SPME step was optimized in terms of adsorbent phase and extraction time. HS-SPME-GC-MS technique was applied to the extraction and anal. of VOCs of healthy and Xf-infected olive trees. More than 100 compounds were identified and the differences between samples were evidenced by the multivariate anal. approach. The results showed the marked presence of Me esters in Xf-infected samples, suggesting their probable involvement in the mechanism of diffusible signal factor. The proposed approach represents an easy and solvent-free method to evaluate the presence of Xf in olive trees, and to evidence volatiles produced by host/pathogen interactions that could be involved in the defensive mechanism of the olive tree and/or in the infective action of Xf.

Phytochemical Analysis published new progress about Acids Role: ANT (Analyte), ANST (Analytical Study). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Synthetic Route of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zhang, Tao; Luan, Yu-Xin; Lam, Nelson Y. S.; Li, Jiang-Fei; Li, Yue; Ye, Mengchun; Yu, Jin-Quan published the artcile< A directive Ni catalyst overrides conventional site selectivity in pyridine C-H alkenylation>, Safety of 3-(Methoxycarbonyl)pyridine, the main research area is alkenylated pyridine preparation; alkyne pyridine alkenylation heterocyclic carbene ligated nickel aluminum catalyst.

Herein, application of bifunctional N-heterocyclic carbene-ligated Ni-Al catalyst in C3-H alkenylation of pyridines was described. This method overrode the intrinsic C2 and/or C4 selectivity, and provided a series of C3-alkenylated pyridines such as I in 43-99% yields and up to 98:2 C3 selectivity. This method not only allowed a variety of pyridine and heteroarene substrates to be used as the limiting reagent, but was also effective for the late-stage C3 alkenylation of diverse complex pyridine motifs in bioactive mols.

Nature Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Safety of 3-(Methoxycarbonyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Heusler, Arne; Fliege, Julian; Wagener, Tobias; Glorius, Frank published the artcile< Substituted Dihydropyridine Synthesis by Dearomatization of Pyridines>, Synthetic Route of 93-60-7, the main research area is dihydropyridine preparation regioselective; pyridine triflic anhydride dearomatization trimethylamine borane; phenyl chloroformate pyridine dearomatization trimethylamine borane; boranes; chemoselectivity; nitrogen heterocycles; reduction; synthetic methods.

The synthesis of a broad variety of N-substituted 1,4-dihydropyridines I [R = H, 3-Me, 3,5-di-Br, etc.; R1 = Tf, CO2Ph] and 1,2-dihydropyridines II [R2 = F, Cl, CF3, Ph, SPh; R3 = H, F, trimethylsilyl] by very mild and selective reduction with amine borane was reported for the first time.

Angewandte Chemie, International Edition published new progress about Dearomatization. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Synthetic Route of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem