Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 935-28-4, name is 2,6-Diethylpyridine. A new synthetic method of this compound is introduced below., 935-28-4
To the 25 mL Schlenk reaction tube was added 0.5 equivalents of NHPI and dried in vacuo for 15 minutes. The oxygen balloon was added and the acetonitrile lmL, 1.0 part by weight of tert-butyl nitrite, 0.5 mmol of 2,6-diethylpyridine were added in an oxygen atmosphere, In the reaction tube with poly tetrafluoro plug after the oil into the pot, 80 C reaction 24h After completion of the reaction, the solvent acetonitrile was concentrated under reduced pressure and the column eluted with petroleum ether / ethyl acetate (nu: 10: 1) to give 2-acetyl-6-ethylpyridine. Product yield 63%, light yellow oil
At the same time, in my other blogs, there are other synthetic methods of this type of compound,935-28-4, 2,6-Diethylpyridine, and friends who are interested can also refer to it.
Reference:
Patent; University of Science and Technology of China; Kang Yanbiao; Liu Jie; (15 pag.)CN107011133; (2017); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem