Category: 971-66-4

Kobayashi, Naomasa published the artcileEffects of new antifouling compounds on the development of sea urchin, Quality Control of 971-66-4, the publication is Marine Pollution Bulletin (2002), 44(8), 748-751, database is CAplus and MEDLINE.

Tributyltin oxide (TBTO) was used worldwide in marine antifouling paints as a biocide for some time. However, it produced toxic effects, especially in marine water/sediment ecosystems. Consequently, its use in antifouling paints was prohibited in many countries. In this study, the toxicity of alternative and/or new antifouling biocides compared with TBTO is assessed by a biol. method. The effects of these chems. on marine species were not well studied. This paper assesses, comparatively, the effects of 8 biocides on sea urchin eggs and embryos. The chems. assessed were TBTO, Irgarol 1051, M1 (the persistent degradation product of Irgarol), Diuron, Zn pyrithione, KH101, Sea-Nine 211, and Cu pyrithione. For these chems., toxicity appears to be in the order Zn pyrithione>Sea-Nine 211>KH101>Cu pyrithione>TBTO>Diuron∼Irgarol 1051>M1. Here, the authors show that zinc pyrithione, Sea-Nine 211, KH101, and copper pyrithione are much more toxic to sea urchins than TBTO or the other chems.

Marine Pollution Bulletin published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Quality Control of 971-66-4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Krossing, Ingo published the artcileBis(tetramethylpiperidino)aluminum halide adducts tmp₂AlX.Do and tetrahaloaluminates of tricoordinated aluminum cations [tmp₂Al(Do)]AlX₄, Formula: C23H20BN, the publication is European Journal of Inorganic Chemistry (1998), 927-939, database is CAplus.

Upon treatment with Lewis bases Do (Do = pyridine bases or THF), the Lewis acids tmp₂AlX (X = Cl, Br, I) are converted exclusively to the monoadducts tmp₂AlX.Do. Crystal and mol. structure of these monoadducts were determined The Al-X bonds of these addition compounds are considerably elongated, indicating a tendency towards the formation of ionic species [tmp₂Al(Do)]X. Due to the steric requirements of the bulky tmp ligands, addition of an excess of the Lewis base does not force these compounds to form tetracoordinated Al cations [tmp₂Al(Do)₂]⁺ or pentacoordinated adducts tmp₂AlX.Do₂. Attempts to prepare ionic representatives by reaction of tmp₂AlX.Do with “ate” complexes of comparatively low nucleophilicity [MY = NaBP₄, AgBPh₄, LiB(C₆F₅)₄, AgBF₄, AgOtos] result in phenylation products (e.g. tmp₂AlPh and BPh₃.py) or tetracoordinated addition compounds tmp₂AlY.Do (Y = anion). However, addition of 1 equivalent of AlX₃ (X = Br, I) initiates halide abstraction with formation of the ionic [tmp₂Al(Do)]AlX₄ species, as indicated by ²⁷Al-NMR data and conductivity measurements. Solid [tmp₂Al(py)]AlI₄ decomposes readily into tmpAlI₂ and tmpAlI₂.py. Addition of non-polar aliphatic solvents to solutions of [tmp₂Al(Do)]AlX₄ leads to slow decomposition into tmp₂AlX and AlX₃.Do. This also occurs in polar donor solvents, where compounds AlX₃.Do are favored due to the formation of penta- or hexacoordinated species AlX₃.Do.Solv_n (n = 1, 2). Semiempirical AM1 calculations reveal the gas-phase stability of the tricoordinated bis(tmp)aluminum cation in the salt [tmp₂AlPy]AlCl₄ as the only representative in a series of calculated Al cations [(R₂N)₂A1Py]AlCl₄ (R₂N = Me₂N, Et₂N, iPr₂N, tmp). According to these calculations, the stability of a given cation increases when tetrachloroaluminate is replaced by tetraiodoaluminate. Ab initio calculations were performed on 2 cations [(H₂N)₂Al(Do)]⁺ (Do = NH₃, py) and indicate very short Al-N bond lengths owing to ionic bonding contributions.

European Journal of Inorganic Chemistry published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Formula: C23H20BN.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Okamura, H. published the artcilePhytotoxic effects of antifouling compounds on nontarget plant species, Application of Triphenyl(pyridin-1-ium-1-yl)borate, the publication is Bulletin of Environmental Contamination and Toxicology (2003), 71(5), 881-886, database is CAplus and MEDLINE.

A battery of bioassays was employed to assess the phytotoxic effects of eight antifouling compounds, i.e., copper pyrithione, Disulfiram, Diuron, KH 101, Sea-Nine 211, Thiram, zinc pyrithione (ZnPT) and Ziram, using non-target freshwater species. The microalga was the most susceptible organism, followed by duckweed and lettuce. The test compounds inhibited algal growth in the following order: Diuron > KH101 > ZnPT > Thiram > Disulfiram > CuPT > Ziram > Sea-Nine 211.

Bulletin of Environmental Contamination and Toxicology published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Application of Triphenyl(pyridin-1-ium-1-yl)borate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Dong, Yifan published the artcileOrientation dependent molecular electrostatics drives efficient charge generation in homojunction organic solar cells, COA of Formula: C23H20BN, the publication is Nature Communications, database is CAplus and MEDLINE.

Organic solar cells usually utilize a heterojunction between electron-donating (D) and electron-accepting (A) materials to split excitons into charges. However, the use of D-A blends intrinsically limits the photovoltage and introduces morphol. instability. Here, we demonstrate that polycrystalline films of chem. identical mols. offer a promising alternative and show that photoexcitation of α-sexithiophene (α-6T) films results in efficient charge generation. This leads to α-6T based homojunction organic solar cells with an external quantum efficiency reaching up to 44% and an open-circuit voltage of 1.61 V. Morphol., photoemission, and modeling studies show that boundaries between α-6T crystalline domains with different orientations generate an electrostatic landscape with an interfacial energy offset of 0.4 eV, which promotes the formation of hybridized exciton/charge-transfer states at the interface, dissociating efficiently into free charges. Our findings open new avenues for organic solar cell design where material energetics are tuned through mol. electrostatic engineering and mesoscale structural control.

Nature Communications published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, COA of Formula: C23H20BN.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Ettel, Viktor published the artcileLocal anesthetics derived from acylaminoacridine, Product Details of C23H20BN, the publication is Chemicke Listy pro Vedu a Prumysl (1957), 1906-8, database is CAplus.

Preparing Xylocaine analogs of the type RNHCOCH₂NEt₂ (I) where R is acridine or its derivatives gave compounds with biol. activity approximating that of Procaine but with considerably lower toxicity. Adding 3 g. ClCH₂COCl to 9.7 g. 9-aminoacridine in 400 ml. Me₂CO, boiling the mixture shortly under reflux, filtering while hot, and evaporating Me₂CO gave 13.3 g. crude 9-(chloroacetylamino)acridine (II), m. 212° (decomposition, from EtOH). Adding 4 g. NHEt₂ to suspension of 5.4 g. II in 250 ml. PhMe, refluxing the mixture 8 hrs., separating the precipitated HCl-salt, evaporating the solution, extracting the base with dilute HCl, and precipitating with aqueous NH₄OH gave 5.5 g. I (R = 9-acridyl), m. 132° (C₆H₆); dihydrochloride, m. 220° (decomposition). Adding MeONa solution from 8 g. Na and 200 ml. MeOH to suspension of 22.6 g. tetrahydroacridine-9-carboxylamide in 45 ml. MeOH, dropping into the mixture with stirring at 20° 28.5 g. Br in 1 hr., raising the temperature to boiling in 1 hr., boiling shortly, cooling down, neutralizing with AcOH, distilling the MeOH, diluting with an equal volume of H₂O, separating the precipitated urethan, decomposing by heating with excess 30% H₂SO₄ 1 hr. on an H₂O-bath, filtering, and precipitating the base with NaOH gave 15 g. 9-amino-1,2,3,4-tetrahydroacridine (III), m. 178° (EtOH). III (20 g.) heated in a sealed tube with 17 g. ClCH₂COCl 4 hrs. to 130-5°, the reaction mixture dissolved in H₂O, the solution filtered with C, and the product precipitated with NH₄OH gave 25 g. 9-(chloroacetylamino)-1,2,3,4-tetrahydroacridine (IV), m. 207° (EtOH). IV (5.5 g.) allowed to react with 4.0 g. NHEt₂ in 250 ml. PhMe gave 6.6 g. I [R = 9-(1,2,3,4-tetrahydroacridyl)], m. 80° (aqueous EtOH); dihydrochloride, m. 235°. Reducing the preceding base (7.7 g.) in boiling EtOH by adding portionwise 200 g. 4% Na-Hg in the presence of NaHCO₃ in a stream of CO₂, cooling the mixture, separating Hg, and distilling EtOH in vacuo gave 7.2 g. I [R = 9-(1,2,3,4,9,10,11,12-octahydroacridyl)], m. 50°.

Chemicke Listy pro Vedu a Prumysl published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Product Details of C23H20BN.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Sazonova, V. A. published the artcileReaction of tetraphenylborocopper with oxo compounds, SDS of cas: 971-66-4, the publication is Zhurnal Obshchei Khimii (1956), 3440-5, database is CAplus.

cf. C.A. 50, 1644d. To 2.25 g. Et benzalacetoacetate in MePh was added at 80° 5 g. pyridine salt of PH₄BCu (I); after filtration, treatment with 10% AcOH, then 10% NaOH and H₂O, there was formed on evaporation 70% Et α-benzhydrylacetoacetate, m. 83-4°, also formed under N in 70% yield. The precipitate formed in the reaction was 96% Cu. Similarly benzalacetylacetone gave 61% α-benzhydryl-α-acetylacetone, m. 115.5°, Et benzalbenzoylacetate gave 98% Et benzhydrylbenzoylacetate, m. 135°, Et α-ethylideneacetoacetate gave over 100% Et α-phenethylacetoacetate, b_4.5 125.5-6°, n_D²⁰ 1.4990; benzalacetophenone gave 29% β,β-diphenylpropiophenone, m. 96-6.5°, and dibenzalacetone and I heated to 160° gave 42% α-benzhydryl-α-benzalacetone, m. 136-6.5°. To 1.14 g. BzH in MePh was added at 80° 5 g. I yielding 0.71 g. Ph₂; a similar failure to add was noted for Ph₂CO and dibenzoylethylene. Addition of 7.5 g. I at 75° under N in CCl₄ gave a brown precipitate containing Ph₃B pyridine salt and Cu salts; evaporation of the filtrate and heating with H₂O 2 hrs. with Ca(OH)₂ and powd. Fe gave BzOH. The brown precipitate extracted with Me₂CO gave on extraction with Me₂CO and treatment of the insoluble part with aqueous KI, a precipitate of CuI and iodine; the filtrate gave triphenylboron pyridine salt, m. 212-18° (decomposition).

Zhurnal Obshchei Khimii published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, SDS of cas: 971-66-4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Ishida, Naoki published the artcileSynthesis of Amine-Borane Intramolecular Complexes through Palladium-Catalyzed Rearrangement of Ammonioalkynyltriarylborates, Recommanded Product: Triphenyl(pyridin-1-ium-1-yl)borate, the publication is Organic Letters (2008), 10(6), 1279-1281, database is CAplus and MEDLINE.

The Pd-catalyzed rearrangement reaction of alkynyltriarylborates having a tertiary ammonium moiety stereoselectively afforded amine-borane intramol. complexes, some of which exhibited significantly strong fluorescence. E.g., under Ar atm. a mixture of Me₂N⁺HCH₂CCB^–Ph₃, 2.5 mol% Pd₂(dba)₃·CHCl₃/P(o-tol)₃ in THF was stirred at 70° to give 91% yield of cyclic dimethyl{(E)-3-phenyl-3-diphenylborylprop-2-enyl}amine.

Organic Letters published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Recommanded Product: Triphenyl(pyridin-1-ium-1-yl)borate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Kamata, Ryo published the artcileAgonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay, Computed Properties of 971-66-4, the publication is Toxicology In Vitro (2018), 335-349, database is CAplus and MEDLINE.

The constitutive androstane receptor (CAR) is a nuclear receptor and transcription factor regulating proteins involved in xenobiotic metabolism Agonist activation of the CAR can trigger metabolic activation and toxification as well as detoxification and clearance; accordingly, xenobiotic substances acting as CAR ligands may pose a threat to human and animal health. The authors used yeast cells transduced with the human CAR and the response pathway to measure the CAR-agonistic activities of 549 synthetic or natural compounds: 216 of the tested compounds exhibited CAR-agonistic effects. Eighty-four percent of CAR-activating compounds were aromatic compounds, and >65% of these active compounds were aromatic hydrocarbons, bisphenols, monoalkyl phenols, phthalates, styrene dimers, di-Ph ethers, organochlorines, and organophosphates. The ten most potent compounds were 4-tert-octylphenol (4tOP; reference substance), 4-nonylphenol, diethylstilbestrol, benzyl Bu phthalate, 2-(4-hydroxyphenyl)-2,4,4-trimethylchroman, o,p’-DDT, methoxychlor, di-Pr phthalate, hexestrol, and octachlorostyrene. The activities of these nine non-reference compounds exceeded 10% of the 4tOP activity. Anal. of para-monoalkyl phenols suggests that branching of the alkyl group and chlorination at the ortho position raises potency. This study provides critical information for identifying the potential of CAR-mediated toxic hazards and for understanding the relevant mechanism.

Toxicology In Vitro published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Computed Properties of 971-66-4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Ishida, Naoki published the artcileStereoselective synthesis of trisubstituted alkenylboranes by palladium-catalysed reaction of alkynyltriarylborates with aryl halides, Name: Triphenyl(pyridin-1-ium-1-yl)borate, the publication is Chemical Communications (Cambridge, United Kingdom) (2007), 4381-4383, database is CAplus and MEDLINE.

The palladium-catalyzed reaction of alkynyltriarylborates with aryl halides afforded trisubstituted alkenylboranes, in which two different aryl groups were installed across the carbon-carbon double bond in a cis arrangement.

Chemical Communications (Cambridge, United Kingdom) published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Name: Triphenyl(pyridin-1-ium-1-yl)borate.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lee, Yao published the artcileViral replication and innate immunity of feline herpesvirus-1 virulence-associated genes in feline respiratory epithelial cells, Category: pyridine-derivatives, the publication is Virus Research (2019), 56-67, database is CAplus and MEDLINE.

Feline herpesvirus-1 (FHV-1) infection occurs worldwide and is a leading cause of respiratory and ocular diseases in cats. Current vaccines reduce the severity of symptoms but do not prevent infection and, therefore, do not provide defense against an establishment of latency and reactivation. We hypothesize that immunomodulation of FHV-1 is the cause of lack in protection and that deletion of virulence/immune modulatory genes of FHV-1 will enhance safety and immunogenicity. Our objective was to use feline respiratory epithelial cell (FREC) cultures to define in vitro growth characteristics and immunomodulation resulting from infection of FRECs with the virulent FHV-1 strain C27 (WT) and glycoprotein C-deletion (gC-), glycoprotein E-deletion (gE-), serine/threonine protein kinase-deletion (PK-), as well as gE and thymidine kinase-double-deletion (gE-TK-) mutants generated by bacterial artificial chromosome mutagenesis. Differentiated FRECs were mock inoculated or inoculated with WT, gC-, gE-, PK-, or gE-TK- mutants. Virus titration and real-time quant. PCR assays were performed on samples collected at 1 hpi followed by 24 h intervals between 24 and 96 hpi to determine growth kinetics. Real-time PCR was used to quantitate IFNa, TNFa, IL-1β, IL-10, and TGFβ-specific mRNA levels. Immunoassays were performed to measure the protein levels of subsets of cytokines/chemokines secreted by FRECs. Inoculation of FRECs with gE-TK- resulted in significantly lower end-point titers than inoculation with WT or gE-. Both PK- and gC- inoculated FRECs also produced significantly lower end-point titers at 96 hpi than WT. Overall, intracellular virus titers were higher than those of extracellular virus. PCR results for viral DNA paralleled the virus titration results. Further, in contrast to WT inoculation, an increase in IFNa and IL-10 mRNA expression was not observed following inoculation with gE-TK- and PK-, but inoculation with gE-TK- and PK- did result in increased TGFβ expression in FRECs compared to responses following infection with WT. Moreover, gE-TK- and PK- blocked the inhibition of IL-8 and neutrophil chemoattractant (KC), which was observed following inoculation with WT. In summary, the results obtained in FRECs may be used to predict the safety and immunogenicity characteristics of these mutants in vivo. Our study highlights the value of the FREC system for studying replication kinetics/immune modulation factors of FHV-1 and screening prospective vaccine candidates before their use in exptl. cats.

Virus Research published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem