Ceccarelli, Simona M.’s team published research in Bioorganic & Medicinal Chemistry Letters in 17 | CAS: 18437-58-6

Bioorganic & Medicinal Chemistry Letters published new progress about 18437-58-6. 18437-58-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 4-Amino-2-picoline, and the molecular formula is C6H8N2, Safety of 4-Amino-2-picoline.

Ceccarelli, Simona M. published the artcileRational design, synthesis, and structure-activity relationship of benzoxazolones: new potent mGlu5 receptor antagonists based on the fenobam structure, Safety of 4-Amino-2-picoline, the publication is Bioorganic & Medicinal Chemistry Letters (2007), 17(5), 1302-1306, database is CAplus and MEDLINE.

A class of potent and stable mGlu5 receptor antagonists was developed by combining information from a high-throughput screening campaign with the structure of the known anxiolytic fenobam. Representative compounds I from this class show favorable pharmacokinetic properties and are active in an in vivo model of anxiety.

Bioorganic & Medicinal Chemistry Letters published new progress about 18437-58-6. 18437-58-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 4-Amino-2-picoline, and the molecular formula is C6H8N2, Safety of 4-Amino-2-picoline.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem