Ceglowski, Michal; Marien, Yoshi W.; Smeets, Sander; De Smet, Lieselot; D′hooge, Dagmar R.; Schroeder, Grzegorz; Hoogenboom, Richard published the artcile< Molecularly Imprinted Polymers with Enhanced Selectivity Based on 4-(Aminomethyl)pyridine-Functionalized Poly(2-oxazoline)s for Detecting Hazardous Herbicide Contaminants>, HPLC of Formula: 3731-53-1, the main research area is molecularly imprinted polymer aminomethylpyridine functionalized polyoxazoline detecting herbicide contaminant; trichlorophenoxyacetate adsorption molecularly imprinted polymer adsorbent.
The detection of hazardous compounds is of importance to control (drinking) water quality. Here, we report the development of poly(2-oxazoline)-based molecularly imprinted polymers (MIPs) for the detection of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). In view of enhanced selectivity of the MIPs, it was hypothesized that incorporation of pyridine groups would lead to stronger interactions with 2,4,5-T. The synthesis of 4-(aminomethyl)pyridine (4-AMP)-functionalized poly(2-methoxycarbonylpropyl-2-oxazoline)s with various degrees of modification was, therefore, investigated via stoichiometric and kinetic control over the functionalization degree. The mol. imprinting of 2,4,5-T is performed by direct amidation of the Me ester side chains with diethylenetriamine. The exptl. data of 2,4,5-T adsorption were interpreted with various models to quantify the adsorption thermodn. and kinetics. The best fit was obtained for a single-site Langmuir model, indicating uniform binding site energies. A further investigation shows that the maximum adsorption capacity is reached at low 4-AMP modification degrees, whereas greater adsorption energies and higher selectivities are observed for higher 4-AMP modification degrees. Finally, the developed 4-AMP-modified MIP adsorbents were successfully used for quantification of 2,4,5-T by direct anal. with ambient mass spectrometry. In comparison with the pure analyte solution, the detection limits decreased by three orders of magnitude.
Chemistry of Materials published new progress about Adsorbents. 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, HPLC of Formula: 3731-53-1.