In 2022,Cesari, Andrea; Casulli, Maria Antonietta; Hashimoto, Takeshi; Hayashita, Takashi published an article in International Journal of Molecular Sciences. The title of the article was 《NMR Investigation of the Supramolecular Complex Formed by a Phenylboronic Acid-Ferrocene Electroactive Probe and Native or Derivatized β-Cyclodextrin》.Category: pyridine-derivatives The author mentioned the following in the article:
Specifically designed electrochem. sensors are standing out as alternatives to enzyme-based biosensors for the sensing of metabolites. In our previous works, we developed a new electrochem. assay based on cyclodextrin supramol. complexes. A ferrocene moiety (Fc) was chem. modified by phenylboronic acid (4-Fc-PB) and combined with two different kinds of cyclodextrins (CDs): β-CD and β-CD modified by a dipicolylamine group (dpa-p-HB-β-CDs) for the sensing of fructose and adenosine-triphosphate (ATP), resp. The aim of the present work is to better comprehend the features underlining the aforementioned complex formation. For the first time, a study about inclusion phenomena between the 4-Fc-PB electroactive probe with β-CD and with dpa-p-HB-β-CD was performed by using NMR (NMR) anal. In particular, we focused on providing insights on the interaction involved and on the calculation of the binding constant of 4-Fc-PB/β-CD supramol. complex, and elucidation about a drift in the time observed during the control experiments of the electrochem. measurements for the 4-Fc-PB/dpa-p-HB-β-CD supramol. complex. In this sense, this paper represents a step further in the explanation of the electrochem. results obtained, pointing out the nature of the interactions present both in the formation of the inclusions and in the sensing with the analytes. In the experiment, the researchers used Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Category: pyridine-derivatives)
Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry.Category: pyridine-derivatives