Chae, Eunhee published the artcileDiscovery of biological evaluation of pyrazole/imidazole amides as mGlu5 receptor negative allosteric modulators, Application In Synthesis of 18437-58-6, the publication is Bioorganic & Medicinal Chemistry Letters (2013), 23(7), 2134-2139, database is CAplus and MEDLINE.
Development of SAR in a 5-aryl-3-acylpyridinyl-pyrazoles and 1-aryl-4-acylpyridinyl imidazoles series of mGlu5 receptor neg. allosteric modulators (mGluR5 NAMs) using a functional cell-based assay is described in this Letter. Anal. of the Ligand-lipophilic efficiency (LipE) of compounds provided new insight for the design of potent mGluR5 neg. allosteric modulators with anti-depressant activities.
Bioorganic & Medicinal Chemistry Letters published new progress about 18437-58-6. 18437-58-6 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 4-Amino-2-picoline, and the molecular formula is C6H8N2, Application In Synthesis of 18437-58-6.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem