Recently I am researching about SULFANE SULFURS; SULFIDE; H2S; MITOCHONDRIA; METABOLISM; EMISSION, Saw an article supported by the Natural Science Foundation Committee of China (NSFC)National Natural Science Foundation of China (NSFC) [81671803]; National Key Research and Development Program [2017YFC0107700]; Outstanding Youth Foundation of Jiangsu Province [GX20171114003, BK20170030]; Fok Ying Tung Education FoundationFok Ying Tung Education Foundation [161033]; Double First-Class University project [CPU2018GY06]; Post-doctoral Innovative Talent Support Program [BX20190389]; Priority Academic Program Development of Jiangsu Higher Education Institutions. Product Details of 91-02-1. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Liang, L; Li, WQ; Zheng, JR; Li, RX; Chen, HY; Yuan, ZW. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone
Hydrogen polysulfides (H2Sn, n > 1) belong to sulfane sulfur in the reactive sulfur species (RSS) family and play significant roles in maintaining biological homeostasis in organisms. The detection of H2Sn in living systems is essential, but further understanding of its intact function in living cells has been limited, owing to the lack of appropriate analytical tools. In this work, a new fluorescent probe PP-PS was designed for the detection of endogenous H2Sn. The probe has a large Stokes shift (178 nm), low detection limit (1 nM), and short response time (1 minute). Besides, PP-PS was successfully applied in the imaging of endogenous H2Sn in lysosomes of living cancer cells, xenograft mouse tumor tissues, and LPS-induced mouse inflammation tissues. These results revealed that the probe PP-PS could act as a new fluorescence imaging tool to study the function of intracellular hydropolysulfides.
About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Liang, L; Li, WQ; Zheng, JR; Li, RX; Chen, HY; Yuan, ZW or concate me.. Product Details of 91-02-1
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem