SDS of cas: 100-54-9In 2021, Yuan, Feixiang;Xie, Shihua;Zhuo, Liang;Wang, Lei;Zhu, Hongjun published 《Metal-Free Synthesis of 2-Aryl Quinazolines via Tandem C-H/N-H Bond Functionalization》. 《ChemistrySelect》published the findings. The article contains the following contents:
The present work provides a facile and highly efficient strategy (ca. ∼92%) for the synthesis of quinazoline compounds e.g., I, which involves tandem C-H/N-H bond functionalization using metal-free conditions without the need for an external oxidant. Meanwhile, the reaction system exhibits good functional group tolerance and a wide substrate scope. Furthermore, corresponding isotope tracking experiments have shown that DMSO acts as a carbon source. Finally, this work affords a new strategy toward the further design and synthesis of heteroaromatic rings.3-Cyanopyridine (cas: 100-54-9) were involved in the experimental procedure.
3-Cyanopyridine(cas: 100-54-9) also shows biological activity against autoimmune diseases, such as murine hepatitis, by inhibiting the proliferation of B cells and T cells.SDS of cas: 100-54-9 This drug is not effective against cancer cells because it does not inhibit DNA synthesis or protein synthesis.