Chen, Hang; Tang, Xiao; Ye, Hebo; Wang, Xinchang; Zheng, Hao; Hai, Yu; Cao, Xiaoyu; You, Lei published their research in Organic Letters in 2021. The article was titled ãEffects of n â?Ï* Orbital Interactions on Molecular Rotors: The Control and Switching of Rotational Pathway and Speedã?Category: pyridine-derivatives The article contains the following contents:
The role of n â?Ï* orbital interactions in the rotational pathway and barrier of biaryl-based mol. rotors was elucidated through a combined exptl. and computational study. The n â?Ï* interaction in the transition state can lead to the acceleration of rotors. The competition between the n â?Ï* interaction and hydrogen bonding further enabled the reversal of the pathway and greasing/braking the rotor in response to acid/base stimuli, thereby creating a switchable mol. rotor. In the experiment, the researchers used 2-Bromonicotinaldehyde(cas: 128071-75-0Category: pyridine-derivatives)
2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Category: pyridine-derivatives