At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Application of C6H4BrNO.
Chen, Helen Y.;Plummer, Christopher W.;Xiao, Dong;Chobanian, Harry R.;DeMong, Duane;Miller, Michael;Trujillo, Maria E.;Kirkland, Melissa;Kosinski, Daniel;Mane, Joel;Pachanski, Michele;Cheewatrakoolpong, Boonlert;Di Salvo, Jerry;Thomas-Fowlkes, Brande;Souza, Sarah;Tatosian, Daniel A.;Chen, Qing;Hafey, Michael J.;Houle, Robert;Nolting, Andrew F.;Orr, Robert;Ehrhart, Juliann;Weinglass, Adam B.;Tschirret-Guth, Richard;Howard, Andrew D.;Colletti, Steven L. research published 《 Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs》, the research content is summarized as follows. A series of biaryl chromans exhibiting potent and selective agonism for the GPR40 receptor with pos. allosteric modulation of endogenous ligands (AgoPAM) were discovered as potential therapeutics for the treatment of type II diabetes. Optimization of physicochem. properties through modification of the pendant aryl rings resulted in the identification of compound I, which possesses an improved metabolic profile while demonstrating sustained glucose lowering.
Application of C6H4BrNO, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.
5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.