The author of 《Improved synthesis of YG-056SP, a potent oxazolidinone antibacterial candidate against multi-drug resistant bacteria》 were Chen, Peng; Zhang, Yinyong; Shi, Chenghui; Meng, Xin; Yang, Yushe; Zhou, Xianli; Guo, Bin. And the article was published in Journal of Chemical Research in 2019. Recommanded Product: 2,5-Dibromopyridine The author mentioned the following in the article:
An improved process for the synthesis of potent oxazolidinone candidate I against multi-drug resistant bacteria was developed. Compared with the original synthetic route, this new approach was two steps shorter, and all of the steps involved simple purifications without column chromatog. More importantly, it avoided the use of explosive azide compounds and expensive metal catalysts. The new reaction conditions were mild and safe, which was more suitable for the scalable synthesis of YG-056SP for preclin. studies. The results came from multiple reactions, including the reaction of 2,5-Dibromopyridine(cas: 624-28-2Recommanded Product: 2,5-Dibromopyridine)
2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Recommanded Product: 2,5-Dibromopyridine