Chen, Zhi-Min; Liu, Jianbo; Guo, Jing-Yao; Loch, Maximillan; DeLuca, Ryan J.; Sigman, Matthew S. published the artcile< Palladium-catalyzed enantioselective alkenylation of alkenylbenzene derivatives>, Application of C13H15F3N2O, the main research area is alkenylarene alkenyl triflate palladium catalyst regioselective enantioselective Heck reaction.
A regioselective and enantioselective palladium-catalyzed relay Heck alkenylation of alkenylbenzene derivatives to construct remote stereocenters was disclosed. Various β-substituted styrenes were readily obtained in moderate yields with good to excellent levels of enantioselectivity. This strategy provided rapid access to enantioenriched δ, ε, ζ and η-alkenyl aryl compounds from simple starting materials. Mechanistic studies suggested that termination of the relay reaction was controlled by affinity of the arene for the Pd complex during migration.
Chemical Science published new progress about Alkenyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 1416819-91-4 belongs to class pyridine-derivatives, and the molecular formula is C13H15F3N2O, Application of C13H15F3N2O.