Chi, Benjamin K.; Widness, Jonas K.; Gilbert, Michael M.; Salgueiro, Daniel C.; Garcia, Kevin J.; Weix, Daniel J. published an article in 2022. The article was titled 《In-Situ Bromination Enables Formal Cross-Electrophile Coupling of Alcohols with Aryl and Alkenyl Halides》, and you may find the article in ACS Catalysis.Recommanded Product: 2-Bromo-5-methylpyridine The information in the text is summarized as follows:
The use of 1° and 2° alcs. in cross-electrophile coupling with aryl and vinyl halides to form C(sp3)-C(sp2) bonds R-R1 [R = 2,2-dimethyl-1,3-dioxolan-4-yl, piperidinyl-1-carboxylate, 4,4-difluorocyclohexyl, etc.; R1 = 5-methylpyridinyl, 6-methoxypyridin-3-yl, 4-fluorophenyl, etc.] in a one-pot strategy utilizing a very fast (<1 min) bromination was reported. The reaction's simple benchtop setup and broad scope (42 examples, 56% ± 15% average yield) facilitated use at all scales. The potential in parallel synthesis applications was demonstrated by successfully coupling all combinations of 8 alcs. with 12 aryl cores in a 96-well plate. In addition to this study using 2-Bromo-5-methylpyridine, there are many other studies that have used 2-Bromo-5-methylpyridine(cas: 3510-66-5Recommanded Product: 2-Bromo-5-methylpyridine) was used in this study.
2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridine is widely used in the precursor to agrochemicals and pharmaceuticals. Also, it is used as an important reagent and organic solvent.Recommanded Product: 2-Bromo-5-methylpyridine