《Chiral Imidazo[1,5-a]pyridine-Oxazolines: A Versatile Family of NHC Ligands for the Highly Enantioselective Hydrosilylation of Ketones》 was published in Organometallics in 2020. These research results belong to Chinna Ayya, Swamy .P.; Varenikov, Andrii; de Ruiter, Graham. SDS of cas: 1122-54-9 The article mentions the following:
Herein the authors report the synthesis and application of a versatile class of N-heterocyclic carbene ligands based on an imidazo[1,5-a]pyridine-3-ylidine backbone that is fused to a chiral oxazoline auxiliary. The key step in the synthesis of these ligands involves the installation of the oxazoline functionality via a microwave-assisted condensation of a cyano-azolium salt with a wide variety of 2-amino alcs. The resulting chiral bidentate NHC-oxazoline ligands form stable complexes with Rh(I) that are efficient catalysts for the enantioselective hydrosilylation of structurally diverse ketones. The corresponding secondary alcs. are isolated in good yields (typically >90%) with good to excellent enantioselectivities (80-95% ee). The reported hydrosilylation occurs at ambient temperatures (40°), with excellent functional group tolerability. Even ketones bearing heterocyclic substituents (e.g., pyridine or thiophene) or complex organic architectures are hydrosilylated efficiently, which is discussed further. In the experimental materials used by the author, we found 4-Acetylpyridine(cas: 1122-54-9SDS of cas: 1122-54-9)
4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. SDS of cas: 1122-54-9