Chutvirasakul, Boonta; Nuchtavorn, Nantana; Macka, Mirek; Suntornsuk, Leena published the artcile< Distance-based paper device using polydiacetylene liposome as a chromogenic substance for rapid and in-field analysis of quaternary ammonium compounds>, Formula: C21H38ClN, the main research area is paper device polydiacetylene liposome chromogenic substance quaternary ammonium compound; Distance-based microfluidic paper-based device; In-field analysis; Polydiacetylene; Quaternary ammonium compounds.
This work presents an affordable distance-based microfluidic paper-based device (μPAD), using polydiacetylene (PDA) liposome as a chromogenic substance with a smartphone-based photo editor, for rapid and in-field anal. of quaternary ammonium compounds (QACs) (e.g., didecyldimethylammonium chloride (DDAC), benzyldimethyltetradecyl ammonium chloride (BAC), and cetylpyridinium chloride (CPC)). In-field anal. of these compounds is important to ensure their antimicrobial activity and user safety since they are widely used as disinfectants in households and hospitals. The μPAD featured a thermometer-like shape consisting of a sample reservoir and a microchannel as the detection zone, which was pre-deposited with PDA liposome. The color change from blue to red appeared in the presence of QACs and the color bar lengths were proportional to the QAC concentrations Reactions of QACs with the PDA required a specific pH range (from pH 4.0 to 10.0) and a readout time of 7 min. Anal. performance characteristics of the device were tested with DDAC, BAC, and CPC showing acceptable specificity, accuracy (96.1-109.4%), and precision (%RSDs ≤ 9.3%). Limits of detection and quantitation were at 20-80 and 70 to 250μM, resp. Feasibility of the newly developed device was demonstrated for in-field anal. of QACs in fumigation solution providing comparable results with those obtained from a colorimetric assay (P > 0.05). The proposed device shows potentials for further applications of other analytes since it offers speed, simplicity, and affordability for in-field anal., especially in remote areas where expertise, resources, and infrastructures are limited.
Analytical and Bioanalytical Chemistry published new progress about Colorimetry. 123-03-5 belongs to class pyridine-derivatives, and the molecular formula is C21H38ClN, Formula: C21H38ClN.