Critical Assessment of the Formation of Ionic-Liquid-Based Aqueous Two-Phase Systems in Acidic Media was written by Claudio, Ana Filipa M.;Ferreira, Ana M.;Shahriari, Shahla;Freire, Mara G.;Coutinho, Joao A. P.. And the article was included in Journal of Physical Chemistry B in 2011.HPLC of Formula: 125652-55-3 This article mentions the following:
The ability of Na2SO4 and ionic liquids to induce the formation of acidic aqueous two-phase systems (ATPS) is investigated. Ternary phase diagrams, tie lines, and tie-line lengths for several systems were determined and reported at 298 K and atm. pressure. Among the ionic liquids studied only those containing long alkyl side chains at the ions and/or anions with low hydrogen bond basicity are capable of undergoing liquid-liquid demixing in the presence of Na2SO4 aqueous solutions Besides the salting-out ability of the inorganic salt, the pH of the aqueous solution plays a crucial role toward the formation of ionic-liquid-based ATPS. In acidic media the range of ionic liquids that are able to undergo ATPS formation is substantially reduced when compared to alk. aqueous salt solutions The use of inorganic salts and ionic liquids to promote acidic ATPS is envisaged as particularly valuable in the extraction of compounds that exhibit low acid dissociation constants In the experiment, the researchers used many compounds, for example, 1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3HPLC of Formula: 125652-55-3).
1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.HPLC of Formula: 125652-55-3