Comparison of 渭-nitrido diiron phthalocyanine – H2O2 and Fenton systems in transformation of poly- and perfluorinated aromatics does not support the involvement of hydroxyl radicals was written by Colomban, Cedric;Sorokin, Alexander B.. And the article was included in Journal of Coordination Chemistry in 2018.Synthetic Route of C5F5N The following contents are mentioned in the article:
渭-Nitrido diiron tetrabutylphthalocyanine, (FePctBu4)2N, in combination with H2O2 can perform an efficient defluorination of heavily fluorinated aromatics via an oxidative pathway. To check whether hydroxyl radicals might be involved in this reaction we have compared catalytic activities of (FePctBu4)2N – H2O2 and FeSO4 – H2O2 systems in the transformation of five differently fluorinated benzenes, perfluoronaphthalene, pentafluoropyridine, and eight functionalized perfluorinated benzenes. In sharp contrast with (FePctBu4)2N – H2O2 system, all fluorinated benzene derivatives were completely stable in the presence of FeSO4 and H2O2 at 60 掳C during 15 h. Perfluorinated aromatic compounds functionalized with electron-donating or electron-withdrawing groups as well as pentafluoropyridine exhibited very low conversions. These results unambiguously show that Fenton chem. is not responsible for the oxidative defluorination of highly fluorinated aromatic compounds performed by the (FePctBu4)2N – H2O2 system. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Synthetic Route of C5F5N).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Synthetic Route of C5F5N