Crichton, Robert R.’s team published research in FEBS Letters in 110 | CAS: 2215-33-0

FEBS Letters published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Quality Control of 2215-33-0.

Crichton, Robert R. published the artcileFerritin iron mobilization by chelating agents, Quality Control of 2215-33-0, the publication is FEBS Letters (1980), 110(2), 271-4, database is CAplus and MEDLINE.

The release of ferritin Fe in vitro by 5 Fe chelators was examined Deferrioxamine B (I) and rhodotorulic acid (II) released the greatest amounts of Fe from ferritin; over 24 h incubation at 37°, I and II released 225 and 250 g-atoms Fe/ferritin mol., resp. Of the other chelators, only pyridine-2-aldehyde-2-pyridylhydrazone (III) gave a reasonable release of 85 g-atoms Fe/ferritin mol. in 24 h. The effects of ascorbate, EDTA, and FMN on Fe release were also studied. FMN (1 mM) almost completely inhibited Fe release by I and II, 2 Fe-chelators currently employed in the treatment of Fe overload; the possible in vivo inhibition of these compounds by endogenous flavins was discussed. In contrast, Fe mobilization by III and bipyridyl was substantially enhanced by FMN.

FEBS Letters published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Quality Control of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem