Crichton, Robert R. published the artcileIron mobilization from ferritin by chelating agents, HPLC of Formula: 2215-33-0, the publication is Journal of Inorganic Biochemistry (1980), 13(4), 305-16, database is CAplus and MEDLINE.
The release of Fe from horse spleen ferritin (I) by the chelating agents, deferrioxamine B (II), rhodotorulic acid (III), 2,3-dihydroxybenzoate (IV), 2,2′-bipyridyl (V), and pyridine-2-aldehyde 2-pyridylhydrazone (VI), was studied in vitro. I prepared by classical procedures involving thermal denaturation released its Fe less effectively than I isolated by a modified procedure that avoided this step. II and III were the most effective in releasing Fe from both preparations of I. When FMN was added, Fe release by II, III, and IV was effectively blocked, whereas both V and VI showed a marked simulation. A substantial increase in Fe release was also observed for V and VI with ascorbate; a less important increase was noted for III. EDTA exerted a marked inhibition of Fe release from I with III, IV, V, and VI. The effects of citrate and oxalate on Fe release by the chelators was small. The effect of the concentration of flavin on Fe release from I by II and V was studied. II was unable to mobilize Fe(II) from I following reduction by reduced FMN, whereas V could rapidly complex Fe(II). The results are discussed in the context of current concepts of storage Fe mobilization in the treatment of Fe overload.
Journal of Inorganic Biochemistry published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, HPLC of Formula: 2215-33-0.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem