Synthesis of 2-pyridinamines and their alkyl derivatives from 2-cyanopyridines was written by Dai, Liyan;Fang, Jun;Wang, Xiaozhong;Chen, Yingqi. And the article was included in Huagong Xuebao (Chinese Edition) in 2007.Recommanded Product: 3,6-Dimethyl-2-pyridinamine This article mentions the following:
The preparation of a series of 2-pyridinamines and their alkyl derivatives is described. The target compounds are synthesized starting from corresponding 2-cyanopyridines, via incomplete hydrolysis in the presence of hydrogen peroxide in the dilute alk. mixture of acetone-2% sodium hydroxide solution, and Hoffmann degradation reaction with freshly made NaBrO. This route is of industrial value because of cheap and readily available materials, moderate reaction conditions and convenient operations. In the experiment, the researchers used many compounds, for example, 3,6-Dimethyl-2-pyridinamine (cas: 823-61-0Recommanded Product: 3,6-Dimethyl-2-pyridinamine).
3,6-Dimethyl-2-pyridinamine (cas: 823-61-0) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Recommanded Product: 3,6-Dimethyl-2-pyridinamine